Saturday
1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: Systems Biology of Motile Cilia and Ciliopathies
Discussion Leader: Khadar Abdi (Duke University, USA)
3:15 pm - 3:50 pm
John Wallingford (University of Texas at Austin, USA)
"Systems Biology of Motile Cilia and Ciliopathies"
3:50 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Effectors of Cilia, Mucus and Mucociliary Interactions
Discussion Leaders: Oanh Hoang (University of Texas MD Anderson Cancer Center, USA) and Jasmim Leal (University of Texas at Austin, USA)
5:30 pm - 5:50 pm
Saurabh Kulkarni (Yale School of Medicine, USA)
"How Cells Count: Basal Body Number Regulation in Multiciliated Cells"
5:50 pm - 6:00 pm
Discussion
6:00 pm - 6:20 pm
Bastien Demouveaux (INSERM / University of Lille / CHRU de Lille, France)
"Mucus Enrichment with CYS Domain from Gel-Forming Mucins Remodels the Mucus Protein Matrix and Hinders Motile Cell Displacements"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Hannah Farley (MRC Harwell Institute, United Kingdom)
"PIERCE1 Mediates Left-Right Patterning Through Ciliary Motility"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Gerard Cantero Recasens (Centre for Genomic Regulation, Spain)
"Different Pools of Calcium Control Baseline and Stimulated Mucin Secretion"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Jeroen Dobbelaere (Max F. Perutz Laboratories, Austria)
"Identification of Novel Ciliogenesis Genes in Drosophila and C. elegans "
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Regulators of Cilia, Mucus and Mucociliary Interactions
Discussion Leaders: Jeroen Dobbelaere (Max F. Perutz Laboratories, Austria) and Saurabh Kulkarni (Yale School of Medicine, USA)
9:00 am - 9:20 am
Jamie Everman (National Jewish Health, USA)
"Airway Epithelial Intelectin-1 Secretion Affects IL-13-Induced Mucus-Driven Airway Dysfunction and Expression of the Gene Is Regulated by an eQTL that Is Associated with Development of Asthma and IBD"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Khadar Abdi (Duke University, USA)
"EGFR Signaling Inhibition via Numb Receptor Trafficking Promotes Multiciliated Ependymal Cell Maturation"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
Dinu Antony (Center for Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Germany)
"Whole Exome Sequencing Reveals MNS1 and DNAH9 as Novel Laterality Defect Genes in Humans"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Jasmim Leal (University of Texas at Austin, USA)
"Mucus-Penetrating Peptides for Improved Transport Across Human Cystic Fibrotic Sputum"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Katherine Joyner (University of Maryland, USA)
"Designing Mucin-Based Hydrogels"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Development
Discussion Leader: Ana Maria Jaramillo (University of Texas MD Anderson Cancer Center, USA)
1:30 pm - 2:30 pm
Panel Discussion
Career Development
Camille Ehre (University of North Carolina at Chapel Hill, USA)
Daniel Lafkas (Genentech Inc., USA)
John Wallingford (University of Texas at Austin, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
