| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Lecture |
| 3:45 pm - 4:15 pm | Barbara Brodsky (Tufts University)
"Three strands of collagen: molecular structure, pathological changes and recombinant applications" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Collagen biochemistry, structure, and regulation |
| Discussion Leaders: Karl Kadler (University of Manchester) and Lesley O'Leary (Rice University) |
| 7:30 pm - 7:50 pm | Katarzyna Kopanska (MRC Human Nutrition Research, Cambridge)
"Is there a role for silicon in collagen biosynthesis?" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Mari Aikio (University of Oulu)
"Collagen XVIII has a role in lipid metabolism" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Szymon Manka (Imperial College London)
"Cooperative hydrophobic interactions between collagen and collagenase trigger collagen unwinding" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Susanta Sarkar (NIH)
"Mechanism of collagen degradation revealed by single-molecule tracking of matrix metalloproteinase MMP-1 on type I collagen fibrils" |
| 9:20 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Collagen networks and basement membranes |
| Discussion Leaders: Billy Hudson (Vanderbilt University) and Louise Kung (University of Manchester) |
| 9:00 am - 9:20 am | Victor Hernandez-Gordillo (Purdue University)
"Establishment of a metal-assembled collagen peptide scaffold for the delivery of human mesenchymal stem cells" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Fei Xu (Univ. of Medicine and Dentistry of New Jersey)
"Computationally modeled self-assembly of higher order structure of collagen peptides" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Isi Ero-Tolliver (Vanderbilt University)
"Enzymatic mechanism of sulfilimine bond formation within basement membranes" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Susan Taylor (University of Manchester)
"Tendon as a model to investigate adhesion formation and prevention" |
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Collagen in health and disease |
| Discussion Leaders: Collin Stultz (MIT) and Jorge Fallas (Rice University) |
| 1:30 pm - 1:50 pm | Ming Fang (University of Michigan)
"The origin of dermis collagen matrix nanomorphology and its relationship with estrogen depletion" |
| 1:50 pm - 2:00 pm | Discussion |
| 2:00 pm - 2:20 pm | Lydia Murray (University of Glasgow)
"Investigation into the mechanisms of Col4a2 mutations in human disease" |
| 2:20 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
