| Saturday |
| 1:30 pm - 4:30 pm | Arrival and Check-in |
| 3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:15 pm - 4:00 pm | Keynote Session: Striking the Balance: Predicting, Modeling, and Restraining Protein Structures |
| Discussion Leader: Rafael Bruschweiler (The Ohio State University, USA) |
| 3:15 pm - 3:45 pm | Wilfred Van Gunsteren (ETH Zurich, Switzerland)
"Sense and Nonsense When Deriving Structural Information from Measured NMR Data" |
| 3:45 pm - 4:00 pm | Discussion |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | Modeling Disorder When It Is Intrinsic with the Help of NMR |
| Discussion Leader: Malene Jensen (Institute of Structural Biology, Grenoble, France) |
| 5:30 pm - 5:45 pm | Gabriella Heller (University of Cambridge, USA)
"Characterisation of IDP-Ligand Binding Mechanisms Using NMR-RAM Simulations" |
| 5:45 pm - 6:00 pm | Discussion |
| 6:00 pm - 6:15 pm | Vanessa Kung (University of Wisconsin - Madison, USA)
"NMR to Study Aqueous Solution Structures of Designed Amyloid Peptides" |
| 6:15 pm - 6:30 pm | Discussion |
| 6:30 pm - 6:45 pm | Ryan Slack (University of Pittsburgh, USA)
"Structural Integrity of the Ribonuclease H Domain in HIV-1 Reverse Transcriptase" |
| 6:45 pm - 7:00 pm | Discussion |
| 7:00 pm - 7:15 pm | Shin-Ichi Tate (Hiroshima University, Japan)
"Functional Significances of the Transient Folding of Intrinsically Disordered Proteins (IDPs) Revealed by Combinatorial Approaches Including High-Speed AFM, SAXS, Molecular Dynamics and NMR" |
| 7:15 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| Sunday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Ensemble Representations of Protein Dynamics: A Matter of Course? |
| Discussion Leader: Tatyana Polenova (University of Delaware, USA) |
| 9:00 am - 9:15 am | Po-chia Chen (Georg-August University, Göttingen, Germany)
"Integrating S/WAXS Information as Constraints in MD Simulations" |
| 9:15 am - 9:30 am | Discussion |
| 9:30 am - 9:45 am | Bertalan Kovacs (Pazmany Peter Catholic University, Hungary)
"Dynamic Structural Ensembles of PDZ Domains of PSD-95" |
| 9:45 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | Thomas Alderson (University of Oxford, United Kingdom)
"NMR Spectroscopic-Based Structural and Dynamical Characterization of HSP27, a Polydisperse Molecular Chaperone" |
| 10:15 am - 10:30 am | Discussion |
| 10:30 am - 10:45 am | Maximo Sanz Hernandez (Imperial College London, United Kingdom)
"Using Oriented Solid-State NMR Data to Restrain Molecular Dynamics Simulations of Multimeric Membrane Proteins" |
| 10:45 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Basic NMR? Predicting and Exploiting Chemical Shifts |
| Discussion Leader: David Wishart (University of Alberta, Canada) |
| 1:30 pm - 1:45 pm | Kari Pederson (University of Georgia, USA)
"Assignment of Sparse 13C Alanine Methyl Resonances in Hsp90 Proteins Using RDCs, PCSs, and NOEs" |
| 1:45 pm - 2:00 pm | Discussion |
| 2:00 pm - 2:15 pm | Stephen Prior (University of Missouri, USA)
"Charge-Triggered Membrane Insertion of Soluble Matrix Metalloproteinase-7, Active in Innate Immunity and Tumors" |
| 2:15 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
