SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Presentations |
| Discussion Leader: Paul Trainor (Stowers Institute, Kansas City, USA) |
7:40 pm - 8:20 pm | Patrick Tam (University of Sydney, Sydney, AUS)
"Head formation in the mouse embryo: signals and genetic switches"
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8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Lauri McCauley (University of Michigan, Ann Arbor, USA)
"Parathyroid hormone: Understanding basic mechanisms fosters a clinical application in craniofacial regeneration"
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9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Neural crest and placodes |
| Discussion Leader: Patrick Tam (University of Sydney, Sydney, AUS) |
9:00 am - 9:25 am | Angela Nieto (Instituto de Neurociencias, Alicante, Spain)
"The ins and outs of the epithelial to mesenchymal transition"
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9:25 am - 9:30 am | Discussion |
9:30 am - 9:55 am | Tatiana Hochgreb (California Institute of Technology, Pasadena, USA)
"Switching on bone: a novel molecular mechanism that modulates timing of jaw ossification"
|
9:55 am - 10:05 am | Discussion |
10:05 am - 10:20 am | Ruchi Bajpai (University of Southern California, Los Angeles, USA)
"The delaminating crest provide insights into craniofacial defects and tumor metastasis"
|
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:10 am | David Raible (University of Washington, Seattle, USA)
"Regulation of sensory neurogenesis in zebrafish neural crest" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Andy Groves (Baylor College of Medicine, Houston, USA)
"Hear-Say: The role of the Foxi3 transcription factor in otic placode induction and craniofacial development" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:10 pm | Berta Alsina (Universitat Pompeu Fabra, Barcelona, Spain)
"Role of Retinoic Acid in Inner Ear Development and Regeneration"
|
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Planar Cell Polarity in Craniofacial Morphogenesis |
| Discussion Leader: Andrea Streit (King's College London, UK) |
7:30 pm - 7:55 pm | John Wallingford (University of Texas, Austin USA)
"Planar cell polarity: from cell biology to human disease"
|
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Philip Beales (University College London, UK)
"Cilia, Complement and Crest in Craniofacial Morphogenesis"
|
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Tom Schilling (University of California Irvine, Irvine, USA)
"The Fat pathway regulates cartilage patterning and polarity"
|
9:15 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Stem Cells |
| Discussion Leader: Yang Chai (University of Southern California, Los Angeles, USA) |
9:00 am - 9:25 am | Joanna Wysocka (Stanford University, Palo Alto, USA)
"What epigenomics can teach us about craniofacial development"
|
9:25 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Ophir Klein (UCSF, San Francisco, USA)
"Genetic and epigenetic regulation of epithelial stem cells in the rodent incisor"
|
10:05 am - 10:20 am | Discussion |
10:20 am - 10:35 am | Coffee Break |
10:35 am - 10:50 am | Hu Zhao (University of Southern California, Los Angeles, USA)
"Arterioles provide a niche for the quiescent dental mesenchymal stem cell"
|
10:50 am - 11:00 am | Discussion |
11:00 am - 11:25 am | Songtao Shi (University of Southern, Los Angeles, USA)
"Orofacial Bone Regeneration: From Clinics to Bench-top and Back"
|
11:25 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Paul Sharpe (Kings College, London UK)
"Mouse incisor MSC niches in growth and repair"
|
12:05 pm - 12:20 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Morphogenesis and Patterned Growth |
| Discussion Leader: Paul Sharpe (Kings College, London UK) |
7:30 pm - 7:55 pm | Hazel Sive (MIT, Boston, USA)
"Regulation of vertebrate mouth formation"
|
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:15 pm | Licia Selleri (Cornell University, New York, USA)
"A Conserved Pbx-Wnt-p63-Irf6 Regulatory Module Controls Face Morphogenesis by Promoting Epithelial Apoptosis"
|
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Irma Thesleff (University of Helsinki, FI)
"Mechanisms of tooth renewal"
|
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:10 pm | Yi-ping Chen (Tulane University, New Orleans, USA)
"BMP signaling regulates palate patterning and development"
|
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | David Clouthier (University of Colorado-Denver, USA)
"Nkx2.5 is a central mediator of lower jaw morphogenesis"
|
9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Human Genetics and Disease Models |
| Discussion Leader: Richard Maas (Harvard University, Boston, USA) |
9:00 am - 9:25 am | Jeff Murray (University of Iowa, USA)
"GWAS and beyond: New mutations/genes/pathways for human cleft lip/palate"
|
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Philippe Soriano (Mt Sinai, New York, USA)
"PDGF Signaling and Craniofacial Development"
|
10:00 am - 10:10 am | Discussion |
10:10 am - 10:25 am | Coffee Break |
10:25 am - 10:40 am | Amy Merrill (University of Southern California, Los Angeles, USA)
"Intranuclear FGFR2 signaling in craniofacial development"
|
10:40 am - 10:50 am | Discussion |
10:50 am - 11:15 am | Paul Trainor (Stowers Institute, Kansas City, USA)
"Ribosome Biogenesis and DNA Damage - Global Processes but Local Effects on Craniofacial Development and Disease"
|
11:15 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Joan Richtsmeir (Penn St, University Park, USA)
"The role of fibroblast growth factor receptors in craniofacial variation, disease and evolution"
|
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | James Martin (Baylor College of Medicine, Houston, USA)
"MicroRnas in Orofacial Clefting"
|
12:20 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Signaling and Disease |
| Discussion Leader: Irma Thesleff (University of Helsinki, FI) |
7:30 pm - 7:55 pm | Scott Fraser (Caltech, Pasadena, USA)
"Multimodal imaging of craniofacial patterning"
|
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Yang Chai (University of Southern California, Los Angeles, USA)
"Alternative TGF-beta signaling mechanism and craniofacial malformations"
|
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Karen Liu (King's College London, UK)
"Signal integration in craniofacial morphogenesis"
|
9:05 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Jeremy Green (King's College London, UK)
"Periodic stripe formation by a Turing-mechanism operating at growth zones in the mammalian palate"
|
9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Evolution |
| Discussion Leader: Joan Richtsmeier (Penn State University, University Park, USA) |
9:00 am - 9:25 am | Matthew Harris (Harvard Medical School, Boston, USA)
"Comparative genetics as a means to understand capacity and constraint in craniofacial development"
|
9:25 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Jeffery Streelman (Georgia Tech, Atlanta, USA)
"Developmental Genetics of Diversity in Regenerating Dentitions"
|
10:05 am - 10:20 am | Discussion |
10:20 am - 10:35 am | Coffee Break |
10:35 am - 10:50 am | Clare Baker (University of Cambridge, UK)
"The development and evolution of vertebrate electroreceptors: a 'sixth sense'"
|
10:50 am - 11:00 am | Discussion |
11:00 am - 11:25 am | Benedikt Hallgrimsson (University of Calgary, Calgary CA)
"The Phenogenomics of Variation in Craniofacial Form"
|
11:25 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Richard Schneider (UCSF, San Francisco, USA)
"Regulation of Jaw Size during Development and Evolution"
|
12:05 pm - 12:20 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Tissue Engineering |
| Discussion Leader: Songtao Shi (University of Southern California, Los Angeles, USA) |
7:30 pm - 7:55 pm | Stephen Murray (The Jackson Laboratory, Bar Harbor, USA)
"KOMP2 and the International Mouse Phenotyping Consortium: Opportunities and resources for the craniofacial research community" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Richard Maas (Harvard University, Boston, USA)
"Gene regulatory networks in early tooth development" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Paul H. Krebsbach (University of Michigan)
"Pluripotent stem cells: opening another avenue for craniofacial regeneration" |
9:05 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Michael Longaker (Stanford University, Palo Alto, USA)
"Skeletal tissue engineering using adipose derived cells" |
9:25 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |