Sunday |
4:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session: Phenomics and Mutagenesis Screen;
Epithelial
and Mesenchymal Morphogenesis: Genomics and Imaging |
| Discussion Leader: Ophir Klein (University of California, San Francisco, USA) |
7:40 pm - 8:20 pm | Lee Niswander (University of Colorado School of Medicine, USA) "Phenomics and Mutagenesis
Screen" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Mark Krasnow (Stanford University School of Medicine, USA) "Elucidating Development and Stem Cells at
Single Cell Resolution" |
9:15 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Functional Genomics
and Clinical Genetics |
| Discussion Leader: Paul Trainor (Stowers Institute for Medical Research, USA) |
9:00 am - 9:30 am | Richard Maas (Brigham and Women's Hospital, Harvard Medical School, USA) "Functional Genomics of Craniofacial Development" |
9:30 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Steve Twigg (University of Oxford, United Kingdom) "A Recurrent Mosaic Mutation of SMO (Smoothened) Is the Major Cause of Curry-Jones Syndrome" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 11:00 am | Bernice Morrow (Albert Einstein College of Medicine, USA) "Craniofacial Anomalies in 22q11 Deletion Syndrome" |
11:00 am - 11:10 am | Discussion |
11:10 am - 11:40 am | Carol Wicking (University of Queensland, Australia) "Ciliopathies: From Human Gene Discovery to Animal Models" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:00 pm | General Discussion |
12:00 pm - 12:30 pm | Poster Previews |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Modelling Developmental Errors |
| Discussion Leader: Paul Sharpe (King's College London, United Kingdom) |
7:30 pm - 8:00 pm | Jeffrey Bush (University of California, San Francisco, USA) "Mouse Genetic and Human iPSC Models of Craniofrontonasal Syndrome Reveal
Basic Mechanisms of Eph/Ephrin Boundary Formation" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Joan Richtsmeier (Pennsylvania State University, USA) "Chondrocranial
and Dermatocranial Associations in Evolution, Development and Disease" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:05 pm | Maria Rita Passos-Bueno (Universidade de Sao Paulo, Brazil) "Modeling Craniofacial Syndromes with the Use of Induced Pluripotent Stem Cells" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Irfan Saadi (University of Kansas Medical Center, USA) "SPECC1L Cytoskeletal Protein Regulates Cell Adhesion and Migration Through PI3K-AKT Signaling During Craniofacial Morphogenesis" |
9:25 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Evolution and Functional Anatomy |
| Discussion Leader: Jeffrey Streelman (Georgia Institute of Technology, USA) |
9:00 am - 9:30 am | Anne Huysseune (Ghent University, Belgium) "Evo-Devo of the Dentition" |
9:30 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Neal Anthwal (King's College London, United Kingdom) "Break Down of Meckel's Cartilage Provides Clues to the Evolution of Mammals" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 11:00 am | Craig Miller (University of California, Berkeley, USA) "Fishing
for the Genetic Basis of Craniofacial Development, Evolution, and Regeneration" |
11:00 am - 11:10 am | Discussion |
11:10 am - 11:25 am | Pierre Le Pabic (University of California, Irvine, USA) "Developmental Basis of Head Shape Evolution in East African Rift Lake Cichlids" |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:45 am | Tetsuto Miyashita (University of Alberta, Canada) "Independent Evolutionary Origins of Serial Patterns in the Vertebrate Head as Corroborated by Compatible Fossil and Developmental Evidence" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:00 pm | General Discussion |
12:00 pm - 12:30 pm | Poster Previews |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Gene Network and Switches |
| Discussion Leader: Ralph Marcucio (University of California, San Francisco, USA) |
7:30 pm - 8:00 pm | Robert Cornell (University of Iowa, USA) "Evidence that Common, Non-Coding Variants Near ARHGAP29 Are Pathogenic for Orofacial Clefting" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Tatjana Sauka-Spengler (University of Oxford, United Kingdom) "Pioneering Chromatin for Neural Crest
Specification" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:05 pm | Yuji Mishina (University of Michigan School of Dentistry, USA) "Enhanced BMP Signaling in Neural Crest Cells Leads to Craniosynostosis" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Jacqueline Hecht (The University of Texas Health Science Center at Houston, USA) "CRISPLD2: From Gene Function to New NSCLP Candidate Gene" |
9:25 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Tissue Patterning: Cellular Mechanisms |
| Discussion Leader: Marianne Bronner (California Institute of Technology, USA) |
9:00 am - 9:30 am | Carole LaBonne (Northwestern University, USA) "Rethinking the Zwischenstrang: Cellular
Mechanisms Underlying the Genesis of Neural Crest" |
9:30 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Laura Ahtiainen (University of Helsinki, Finland) "Cellular Mechanisms Driving Tooth Budding Morphogenesis" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 11:00 am | James Martin (Baylor College of Medicine, USA) "Hippo Signaling in Craniofacial Development" |
11:00 am - 11:10 am | Discussion |
11:10 am - 11:40 am | Mai Har Sham (The University of Hong Kong, Hong Kong SAR China) "Eya1 and Notch Signaling in Branchial Epithelium Development" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Jimmy Hu (University of California, San Francisco, USA) "The Regulation of Adult Incisor Stem Cells by YAP/TAZ and Hippo Signalling" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Eric Liao (Harvard Medical School, USA) "Diverse Roles for Wnt Pathway Members in Regulation of Axial Patterning and Convergent Extension During Palate Morphogenesis" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Organ Formation |
| Discussion Leader: Yang Chai (University of Southern California, USA) |
7:30 pm - 8:00 pm | Clare Baker (University of Cambridge, United Kingdom) "The Development and Evolution of Lateral Line
Electroreceptors" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Matthew Hoffman (National Institute of Dental and Craniofacial Research, NIH, USA) "Regulatory Inputs Driving Salivary Gland Development and
Regeneration" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:05 pm | Andrea Streit (King's College London, United Kingdom) "Making Inner Ears: A Gene Network Approach" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | David Clouthier (University of Colorado Anschutz Medical Campus, USA) "Hand2 and Twist1 Control Vascular Development of the Lower Jaw" |
9:25 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
9:00 am - 12:30 pm | Tissue Engineering
and Repairs |
| Discussion Leader: Irma Thesleff (University of Helsinki, Finland) |
9:00 am - 9:30 am | Warren Grayson (Johns Hopkins University, USA) "3D-Printed Scaffolds and Stem Cells for Regeneration of Vascularized Craniofacial
Bone" |
9:30 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Karen Liu (King's College London, United Kingdom) "SOSTDC1-Dependent Repair of Calvarial Bone Defects Using Adipose-Derived Stem Cells" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 11:00 am | Derk Joester (Northwestern University, USA) "Interfaces and Interphases in Tooth Biominerals" |
11:00 am - 11:10 am | Discussion |
11:10 am - 11:25 am | Hu Zhao (Baylor College of Dentistry, USA) "In Vivo Identity and Niche of Periodontal Ligament Stem Cells" |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:45 am | Eric Van Otterloo (University of Colorado Anschutz Medical Campus, USA) "Tissue Specific Redundancy of TFAP2 Family Members During Craniofacial Patterning" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:00 pm | General Discussion |
12:00 pm - 12:30 pm | Poster Previews |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Formshaping: Skull and Face |
| Discussion Leader: James Martin (Baylor College of Medicine, USA) |
7:30 pm - 8:00 pm | Sevan Hopyan (The Hospital for Sick Children, Canada) "Branchial
Arch Morphogenesis" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:25 pm | Amy Merrill-Brugger (University of Southern California, USA) "Connecting Tendon to Bone in Craniofacial Development" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:45 pm | Dany Adams (Tufts University, USA) "Craniofacial Morphogenesis Regulation by Ion-Flux Dependent Signals: The Etiology of Craniofacial Anomalies Associated with Channelopathies" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Ralph Marcucio (University of California, San Francisco, USA) "Murder, Transformation, and Rebirth in the Skeletal System" |
9:20 pm - 9:30 pm | Discussion |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |