Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Heterogeneity of Dendritic Properties from Rodents to Humans
Discussion Leader: Greg Stuart (Australian National University, Australia)
7:40 pm - 8:00 pm
Stephen Smith (Allen Institute for Brain Science, USA)
"Transcriptomic Evidence for Dense Peptidergic Modulation Networks in Mouse and Human Cortex"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Serena Dudek (National Institute of Environmental Health Sciences, NIH, USA)
"Diversity of Dendritic Morphology and Synaptic Effectiveness in Mouse CA2 Pyramidal Neurons"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
Mark Harnett (Massachusetts Institute of Technology, USA)
"Integration and Computation in Cortical Pyramidal Neuron Dendrites"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Molecular Signaling Mechanisms in Dendrites
Discussion Leader: Erin Schuman (Max Planck Institute for Brain Research, Germany)
9:00 am - 9:20 am
Ryohei Yasuda (Max Planck Florida Institute for Neuroscience, USA)
"Postsynaptic Signal Processing in Single Dendritic Spines"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Gentry Patrick (University of California, San Diego, USA)
"Activity-Dependent Protein Degradation in Dendrites via Ubiquitin and the Endolysosomal Pathway"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Jason Shepherd (University of Utah, USA)
"Viral-Like Mechanisms of Dendritic RNA Intercellular Trafficking"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Brenda Bloodgood (University of California, San Diego, USA)
"Transcription Factor mRNA in the Dendrites"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Paul Donlin-Asp (Max Planck Institute for Brain Research, Germany)
"Local Protein Synthesis Is a Ubiquitous Feature of Pre- and Postsynaptic Neuronal Compartments"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Heike Blockus (Columbia University, USA)
"A Novel Neurexin-Slit-Robo2 Complex Links Synaptic Specificity to Circuit Function in the Hippocampus"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Kim Raab-Graham (Wake Forest School of Medicine, USA)
"Titrating Synapse Number to Treat Major Depressive Disorder in Fragile X Syndrome"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
Organizer: Elly Nedivi (Massachusetts Institute of Technology, USA)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Synaptic Competition and Homeostasis on Dendritic Segments
Discussion Leader: Hollis Cline (The Scripps Research Institute, USA)
7:30 pm - 7:50 pm
Kristen Harris (University of Texas at Austin, USA)
"Resources that Support Dendritic Spine Clusters"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Thomas Oertner (University of Hamburg, Germany)
"How Does the Brain Tell Right from Wrong Connections?"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Yukiko Goda (RIKEN Center for Brain Science, Japan)
"Regulating Presynaptic Strength Diversity in Hippocampal CA1 Pyramidal Neurons"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Tara Keck (University College London, United Kingdom)
"Homeostatic Compensation in Single Synapses Following Loss of Visual Input"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Modulatory Control of Dendritic Integration and Plasticity
Discussion Leader: Jun Ding (Stanford University, USA)
9:00 am - 9:20 am
Michael London (Hebrew University of Jerusalem, Israel)
"Adrenergic Modulation Regulates Dendritic Excitability of Layer 5 Pyramidal Neurons"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Kevin Bender (University of California, San Francisco, USA)
"SCN2A in Autism Spectrum Disorder"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Simon Chen (University of Ottawa, Canada)
"Circuit Mechanisms Underlying Delayed Motor Learning in the 16p11.2+/- Mouse Model of Autism"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Stephen Williams (University of Queensland, Australia)
"Cholinergic Control of Dendritic Integration: Two Mechanisms in Two Circuits"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Yevgenia Kozorovitskiy (Northwestern University, USA)
"Ketamine Re-Engages Dopaminergic Modulation to Drive De Novo Spinogenesis After Aversive Learning"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Won Chan Oh (University of Colorado School of Medicine, USA)
"Dysregulation of Mesoprefrontal Dopamine Circuit Mediates Early Life Stress-Induced Excitatory Synaptic Dysfunction"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Haining Zhong (Vollum Institute, Oregon Health and Science University, USA)
"Imaging Neuromodulatory cAMP/PKA Signaling in Neuronal Dendrites"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Dendritic Input Clustering and Computation
Discussion Leader: Judit Makara (Institute of Experimental Medicine, Hungarian Academy of Sciences, Hungary)
7:30 pm - 7:50 pm
Mriganka Sur (Massachusetts Institute of Technology, USA)
"Locally Coordinated Synaptic Plasticity in Visual Cortex Neurons and Circuits"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Bartlett Mel (University of Southern California, USA)
"Conditions that Maximize the Spatial Dimensionality of Dendritic Computation"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Alcino Silva (University of California, Los Angeles, USA)
"Molecular Cellular and Systems Mechanisms that Allocate Information Within Dendrites and Neuronal Ensembles: Implications for Memory"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Inbal Israely (Columbia University, USA)
"Activity Driven Synaptic Competition and Spine Structural Dynamics in Health and Disease"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Dendritic Mechanisms in Sensory and Motor Representation
Discussion Leader: Fritjof Helmchen (University of Zurich, Switzerland)
9:00 am - 9:20 am
Randy Bruno (Columbia University, USA)
"Reinforcement Learning Recruits Apical Dendrites in Primary Sensory Cortex"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Jerry Chen (Boston University, USA)
"Context-Dependent Sensory Processing Across Primary and Secondary Somatosensory Cortex During a Tactile Working Memory Task"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Lucy Palmer (Florey Institute of Neuroscience and Mental Health, Australia)
"Enhanced Neural Encoding During Sensory Association"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
John Bekkers (John Curtin School of Medical Research, Australian National University, Australia)
"NMDA Receptor-Dependent Dendritic Excitability in the Piriform Cortex In Vivo "
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Alon Korngreen (Bar-Ilan University, Israel)
"Dendritic Integration and Synaptic Plasticity Modulating Basal Ganglia Output"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Gwendolin Schoenfeld (University of Zurich, Switzerland)
"Functional Heterogeneity in Apical Tufts of Specific L5 Projection Neurons in Barrel Cortex During Tactile Discrimination Learning"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Mehmet Fisek (University College London, United Kingdom)
"Inter-Areal Coordination and Dendritic Integration in Visual Cortex"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Dendritic Mechanisms in Behavior
Discussion Leader: Michael Hausser (University College London, United Kingdom)
7:30 pm - 7:50 pm
Nathalie Rochefort (University of Edinburgh, United Kingdom)
"Dendritic Integration of Visual and Locomotion-Related Inputs in V1 Layer V Pyramidal Neurons"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Mayank Mehta (University of California, Los Angeles, USA)
"Dynamics of Cortical Dendritic Membrane Potential and Spikes in Freely Behaving Rats"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Ninglong Xu (Institute of Neuroscience, Chinese Academy of Sciences, China)
"Dendritic Mechanisms for Perceptual Decision-Making in Projection-Defined Layer 5 Cortical Neurons"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Aaron Kerlin (University of Minnesota, USA)
"Functional Clustering of Dendritic Activity During Decision-Making"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Novel Dendritic Long-Term Plasticity and Learning Mechanisms
Discussion Leader: Anthony Holtmaat (University of Geneva, Switzerland)
9:00 am - 9:20 am
Christine Grienberger (Baylor College of Medicine, USA)
"Dendritic Plateau Potentials Shape CA1 Representations"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Claudia Clopath (Imperial College London, United Kingdom)
"Interplay Between Somatic and Dendritic Inhibition Promotes the Emergence and Stabilization of Place Fields"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Daniel Dombeck (Northwestern University, USA)
"The Functional Organization of Synaptic Input to Place Cells"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Steven Siegelbaum (Columbia University, USA)
"Dendritic Spikes Gate Hippocampal Synaptic Plasticity and Memory"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Yingxi Lin (SUNY Upstate Medical University, USA)
"Functionally Distinct Neuronal Ensembles Within the Memory Engram"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Masanori Murayama (RIKEN Center for Brain Science, Japan)
"Dendritic Activity for Memory Consolidation During NREM Sleep"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Balazs Rozsa (Institute of Experimenal Medicine, Hungarian Academy of Sciences, Hungary)
"Sharp Wave-Ripple Associated Dendritic Spikes in Parvalbumin-Expressing Hippocampal Interneurons in Awake Mice"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Deep Learning and Neuromorphic Computing
Discussion Leader: Nelson Spruston (Janelia Research Campus, Howard Hughes Medical Institute, USA)
7:30 pm - 7:50 pm
Tomoki Fukai (Okinawa Institute of Science and Technology / RIKEN Center for Brain Science, Japan)
"Temporal Feature Analysis by Self-Supervising Dendritic Neurons"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Julie Grollier (Unité Mixte de Physique CNRS/Thales, France)
"Towards Deep Learning with Emerging Nanodevices"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Willem Wybo (University of Bern, Switzerland)
"The Neuronal Impedance Matrix as a Guide Towards Understanding Dendritic Computation"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Subutai Ahmad (Numenta, USA)
"Active Dendrites and Sparse Representations for Deep Learning"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure