Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Cross-Cutting Themes in Dendrites Research
Discussion Leader: Kristen Harris (University of Texas at Austin, United States)
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:15 pm
Hollis Cline (The Scripps Research Institute, United States)
"Optic Tectal Neurons Recognize Complex Spatiotemporal Image Transformations"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:50 pm
Jackie Schiller (Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Israel)
"Cell Type Dependent Computations in Primary Motor Cortex"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:25 pm
Yiota Poirazi (Foundation for Research & Technology - Hellas, Greece)
"Dendritic Contributions to Biological and Machine Learning"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Local Protein Dynamics in Dendrites
Discussion Leader: Yasunori Hayashi (Kyoto University, Japan)
9:00 am - 9:25 am
Chao Sun (DANDRITE, Aarhus University, Denmark)
"Dendritic Protein Synthesis and Degradation Machinery"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
Emily Osterweil (University of Edinburgh, United Kingdom)
"The Long and Short of Unbalanced Translation in Fragile X"
10:00 am - 10:10 am
Discussion
10:10 am - 10:25 am
Tanja Fuchsberger (University Of Cambridge, United Kingdom)
"Postsynaptic Reactivation-Induced Plasticity of Hippocampal Neurons Requires Protein Synthesis"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Boaz Mohar (HHMI Janelia Research Campus, United States)
"Brain-Wide Measurement of Protein Turnover with High Spatial and Temporal Resolution"
11:25 am - 11:35 am
Discussion
11:35 am - 12:00 pm
Ezgi Hacisuleyman (The Rockefeller University, United States)
"Dissecting Activity-Driven Synaptic RNA and Translational Regulation"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Matt Oliver (Duke University, United States)
"New SINAPS Reporters for Real-Time and Spatial Imaging of Protein Synthesis in Synaptic Plasticity"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizer: Corette Wierenga (Radboud University Nijmegen, The Netherlands)
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Dendrites as Computational Units
Discussion Leader: Mark Harnett (Massachusetts Institute of Technology, United States)
6:00 pm - 6:25 pm
Kwabena Boahen (Stanford University, United States)
"Dendrocentric Learning: The Future of Artificial Intelligence"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 7:00 pm
Marla Feller (University of California, Berkeley, United States)
"Retinal Waves and Direction Selectivity: Is there a Role for Spontaneous Activity in Development of a Dendritic Computation?"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:35 pm
Nikolai Dembrow (University of Washington, United States)
"Dendritic Computation of Naturalistic Inputs"
7:35 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Srikanth Ramaswamy (Newcastle University, United Kingdom)
"Multi-Scale Effects of Neuromodulatory Signalling in the Neocortex"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Dendritic Plasticity Mechanisms
Discussion Leader: Nelson Spruston (Janelia Research Campus, Howard Hughes Medical Institute, United States)
9:00 am - 9:25 am
Jun Ding (Stanford University, United States)
"Motor Learning-induced Convergence of Motor Engram Neuron Outputs onto Clusters of Dendritic Spines"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
Julijana Gjorgjieva (Technical University of Munich, Germany)
"Shaping Dendritic Morphologies and Synaptic Organization through Activity-Dependent Plasticity"
10:00 am - 10:10 am
Discussion
10:10 am - 10:25 am
Diane Bissen (Brandeis University, United States)
"Structural Plasticity Mediating Vision-dependent Naturalistic Learning in Mouse Visual Cortex"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Attila Losonczy (Columbia University, United States)
"Dendritic and Synaptic Mechanisms of Memory Encoding and Consolidation in the Hippocampus"
11:25 am - 11:35 am
Discussion
11:35 am - 12:00 pm
Ivo Spiegel (Weizmann Institute of Science, Israel)
"Regulation of Plasticity in the Adult Cortex by Dendrite-targeting Interneurons"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Simon Chamberland (New York University School of Medicine, United States)
"Registration Receipt Functional Specialization of Hippocampal Somatostatin-Expressing Interneurons"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Dendrites in Development
Discussion Leader: Hollis Cline (The Scripps Research Institute, United States)
6:00 pm - 6:25 pm
Maya Shelly (Stony Brook University, United States)
"Directed Mechanisms for Apical Dendrite Development during Neuronal Polarization"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 6:45 pm
Aicha Haji Ali (Max Planck of Neurobiology, Germany)
"How do Dendrites know in which Direction they should grow? A Time-Lapse Imaging Study on Drosophila T4 Neurons"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:15 pm
Ania Majewska (University of Rochester, United States)
"Microglial Roles in Synaptic Development"
7:15 pm - 7:25 pm
Discussion
7:25 pm - 7:50 pm
Christian Lohmann (Netherlands Institute for Neuroscience, The Netherlands)
"Development of Synaptic Input Structure of Visual Cortex Dendrites"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Dendritic Role in Circuit Function
Discussion Leader: Christine Grienberger (Brandeis University, United States)
9:00 am - 9:25 am
Inbal Goshen (Hebrew University of Jerusalem, Israel)
"Astrocytes and Higher Brain Functions"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
Antoine Adamantidis (University of Bern, Switzerland)
"All-optical Dissection of Cortical Activity during REM Sleep"
10:00 am - 10:10 am
Discussion
10:10 am - 10:25 am
Tatjana Tchumatchenko (Universitätsmedizin der Johannes Gutenberg Universität Mainz, Germany)
"Dendritic Contribution to the Energy Budget of a Neural Circuit"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Michael Hausser (., United Kingdom)
"Computations in Single Dendrites in Vivo"
11:25 am - 11:35 am
Discussion
11:35 am - 12:00 pm
Wei-Chung Allen Lee (Boston Children's Hospital / Harvard Medical School, United States)
"Synaptic Wiring Motifs Supporting Motor Control and Decision-Making"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Anna Schroeder (University of Freiburg, Germany)
"Inhibitory Top-Down Projections from Zona Incerta Mediate Neocortical Memory"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Dendritic Integration During Behavior
Discussion Leader: Fritjof Helmchen (University of Zurich, Switzerland)
6:00 pm - 6:25 pm
Michael Higley (Yale University, United States)
"Paradoxical GABAergic Regulation of Dendritic Calcium Signaling"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 7:00 pm
Angus Silver (University College London, United Kingdom)
"Decoding Activity Patterns Across Pyramidal Cell Dendritic Trees during Spontaneous Behaviours"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:35 pm
Stefan Remy (Leibniz Institute for Neurobiology Magdeburg, Germany, Germany)
"Pathway-Selective Input-Output Transformation of Subicular Pyramidal Neurons during Behavior"
7:35 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Valerio Francioni (Massachusetts Institute of Technology, United States)
"Backpropagation-Like Error Signals in Apical Dendrites of Cortical Neurons during a Brain-Computer Interface Task"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Synaptic Organization and Plasticity
Discussion Leader: Ryohei Yasuda (Max Planck Florida Institute for Neuroscience, United States)
9:00 am - 9:25 am
Pablo Castillo (Albert Einstein College of Medicine, United States)
"BDNF Induces its own Release to Mediate Presynaptic Plasticity"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
Cécile Charrier (Institut de Biologie de l'École Normale Supérieure, France)
"CTNND2 Moderates Neuronal Excitation and Links Human Evolution to Prolonged Synaptic Development in the Neocortex"
10:00 am - 10:10 am
Discussion
10:10 am - 10:25 am
Léa Caya-Bissonnette (University of Ottawa, Canada)
"Cellular Substrate of Eligibility Trace Permissive to Behavioral Timescale Plasticity"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Katrin Willig (Max Planck Institute for Multidisciplinary Sciences, Germany)
"In Vivo STED Microscopy of the Synaptic Nanoorganization"
11:25 am - 11:35 am
Discussion
11:35 am - 12:00 pm
Yoshiyuki Kubota (National Institute for Physiological Sciences, Japan)
"Cortical Spine Dynamics and Microcircuit Remodeling during Motor Learning"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Alessio Attardo (Leibniz Institute of Neurobiology, Germany)
"Structural Synaptic Instability, a Bug or a Feature for Hippocampal Memory?"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
The Role of Wiring Specificity in Dendritic Function
Discussion Leader: Lucy Palmer (Florey Institute of Neuroscience and Mental Health, University of Melbourne, Australia)
6:00 pm - 6:25 pm
Jeff Lichtman (Harvard University, United States)
"Rare Strong and Common Weak Axonal Input to Dendrites"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 6:45 pm
David Wong-Campos (Harvard University, United States)
"In Vivo Voltage Imaging and Optogenetics Reveal Mechanisms of Dendritic Integration"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:15 pm
Arthur Konnerth (Institute of Neuroscience, Technical University of Munich, Germany, Germany)
"Thalamo-Cortical Activation at Single-Synapse Resolution in Vivo"
7:15 pm - 7:25 pm
Discussion
7:25 pm - 7:50 pm
Beatriz Rico (King's College London, United Kingdom)
"Molecular Programs Orchestrating the Synaptic Specificity of Cortical Circuitries"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure