Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Morphogenesis |
| Discussion Leader: Maxwell Heiman (Harvard Medical School, Boston Children's Hospital, USA) |
7:40 pm - 8:00 pm | Alexander Schier (Harvard University, USA) "Nodal-Lefty Interaction During Pattern Formation" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Poster Previews |
8:30 pm - 8:40 pm | Anne-Marie Ladouceur (University of North Carolina, USA) "Scaling Chromosome Compaction to Cell Size" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 9:00 pm | Poster Previews |
9:00 pm - 9:20 pm | Jason Lieb (University of Chicago, USA) "Single-Cell Blastomere Transcriptomes in Early C. elegans Development" |
9:20 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Epigenetic Control of Development |
| Discussion Leader: Jayaraj Rajagopal (Harvard Medical School, USA) |
9:00 am - 9:20 am | Nancy Papalopulu (University of Manchester, United Kingdom) "The Role of a Negative Feedback Circuit in Tuning Cell State Transitions" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Cara Gottardi (Northwestern Feinberg School of Medicine, USA) "Catenin Proteins in Adhesion and Transcription: Conserved Relationships at the Plasma Membrane and Nucleus?" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:25 am | Poster Previews |
10:25 am - 10:55 am | Coffee Break |
10:55 am - 11:05 am | Melissa Harrison (University of Wisconsin - Madison, USA) "Mechanisms Driving Genome Reprogramming and Transcriptional Activation in the Early Embryo" |
11:05 am - 11:10 am | Discussion |
11:10 am - 11:30 am | John Rinn (Harvard University / Broad Institute, USA) "Regulatory Roles of RNA Repeats" |
11:30 am - 11:40 am | Discussion |
11:40 am - 11:50 am | Cristina Pujades (Universitat Pompeu Fabra, Spain) "Building the Inner Ear: Cellular Dynamics of Neurosensory Progenitors During Embryonic Development" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:15 pm | Bradley Cairns (University of Utah, USA) "Chromatin and Transcription Dynamics of Germline Cells and Early Embryos" |
12:15 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Cellular Polarity |
| Discussion Leader: Cliff Brangwynne (Princeton University, USA) |
7:30 pm - 7:50 pm | Kathryn Anderson (Memorial Sloan Kettering Cancer Center, USA) "Morphogenesis in the Early Mouse Embryo" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:10 pm | Chen-Hui Chen (Duke University Medical Center, USA) "Large-Scale Surveillance of Epithelial Cell Dynamics During Tissue Regeneration" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:35 pm | Jessica Feldman (Stanford University, USA) "Patterning the Microtubule Cytoskeleton During Development" |
8:35 pm - 8:45 pm | Discussion |
8:45 pm - 9:00 pm | Poster Previews |
9:00 pm - 9:20 pm | Susan Mango (Harvard University, USA) "Coordinating Morphogenesis and the Diversity of Epithelium Formation" |
9:20 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Small ncRNAs in Development |
| Discussion Leader: Julie Claycomb (University of Toronto, Canada) |
9:00 am - 9:25 am | Ann Rougvie (University of Minnesota, USA) "Control of Developmental Transitions in C. elegans" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:20 am | Victor Ambros (University of Massachusetts Medical School, USA) "Micro RNA Pathways and Developmental Robustness in C. elegans" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:25 am | Scott Kennedy (Harvard Medical School, USA) "Germline Immortality and RNAi Inheritance" |
11:25 am - 11:35 am | Discussion |
11:35 am - 12:20 pm | Gary Rukun (Massachusetts General Hospital, USA) "Tiny RNA Surveillance of Genetic Invasions" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Stem Cell Biology |
| Discussion Leader: Andrea Pauli (Harvard University, USA) |
7:30 pm - 7:50 pm | Judith Kimble (University of Wisconsin - Madison / Howard Hughes Medical Institute, USA) "Notch Signaling and Its Control of a Stem Cell Pool" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:10 pm | Mary Donohoe (Burke Medical Research Institute, Weill Cornell Medical College, USA) "An Anti-Sense LncRNA Regulates the Endoderm Pioneer Factor GATA6 Providing a Scaffold for Chromatin Modifiers" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:30 pm | Poster Previews |
8:30 pm - 8:50 pm | David Bilder (University of California, Berkeley, USA) "PCP Morphogenesis in an Edgeless Epithelium" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Jayaraj Rajagopal (Harvard Medical School, USA) "Novel Modes of Stem Cell Function" |
9:20 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Intercellular Signaling |
| Discussion Leader: Anne Brunet (Stanford University, USA) |
9:00 am - 9:20 am | Roberto Mayor (University College London, United Kingdom) "Cellular Basis of Collective Migration" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:40 am | Yashi Ahmed (Dartmouth College, Geisel School of Medicine, USA) "Wnt Pathway Activation by ADP-Ribosylation" |
9:40 am - 9:45 am | Discussion |
9:45 am - 9:55 am | Blair Benham-Pyle (Stanford University, USA) "Mechanical Strain Induces E-Cadherin Dependent Yap1 and β-Catenin Activation to Drive Cell Cycle Progression" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Francesca Peri (European Molecular Biology Laboratory, Germany) "The Brain Under Surveillance: The Role of Neuronal Microglial Interactions in the Development and Repair of the CNS" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Jean-Paul Vincent (National Institute for Medical Research, United Kingdom) "Trafficking and Regulation of the WNT Signal in Developing Epithelia" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Steffen Scholpp (Karlsruhe Institute of Technology (KIT), Germany) "Wnt Transport in a Vertebrate Tissue" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Maxwell Heiman (Harvard Medical School, Boston Children's Hospital, USA) "GRDN-1 Creates a Neuron-Glia Attachment that Couples Embryo Elongation to Dendrite Extension" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Darren Gilmour (European Molecular Biology Laboratory, Germany) "The Collective Cell Biology of Organ Assembly" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Self Assembly Within Cells |
| Discussion Leader: Jessica Feldman (Stanford University, USA) |
7:30 pm - 7:50 pm | Cliff Brangwynne (Princeton University, USA) "Developmental Regulation of Organelle Size, Drop by Drop" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:10 pm | Sebastian Streichan (Kavli Institute for Theoretical Physics, Univeristy of California, Santa Barbara, USA) "Development Plain and Simple: Using Cartography to Infer Forces Driving Embryogenesis" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:35 pm | Vladimir Denic (Harvard University, USA) "A Molecular Switch that Turns on Selective Autophagy" |
8:35 pm - 8:45 pm | Discussion |
8:45 pm - 8:55 pm | Michel Bagnat (Duke University, USA) "Notochord Vacuoles Function as a Hydrostatic Scaffold for Spine Morphogenesis" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Dominique Bergmann (Stanford University, USA) "Going Your Own Way: Coordinating Local and Global Polarities in an Epidermal Lineage" |
9:20 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Transgenerational Inheritance |
| Discussion Leader: Antony Jose (University of Maryland, College Park, USA) |
9:00 am - 9:20 am | Anne Brunet (Stanford University, USA) "Epigenetic Mechanisms of Aging Regulation" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:45 am | Scott Berry (John Innes Centre, United Kingdom) "Chromatin-Based Memory of Temperature Signals in Regulation of the Floral Transition" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:05 am | Kai Yuan (University of California, San Francisco, USA) "Transgenerational Inheritance of Heterochromatin Formation in Drosophila Early Embryo Revealed by TALE-Lights Imaging" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:30 am | Julie Claycomb (University of Toronto, Canada) "Small RNA Pathways as Guardian of Germline Gene Expression" |
10:30 am - 10:40 am | Discussion |
10:40 am - 11:10 am | Coffee Break |
11:10 am - 11:20 am | Ryan Baugh (Duke University, USA) "Cell-Nonautonomy
of Daf-16/FOXO in Regulation of Developmental Arrest and Early Larval Starvation in C. elegans Affects a Variety of Life-History Traits over Multiple Generations" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:45 am | Oliver Rando (University of Massachusetts Medical School, USA) "Paternal Dietary Effects on Preimplantation Gene Regulation" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:15 pm | Danesh Moazed (Harvard Medical School, USA) "Epigenetic Inheritance" |
12:15 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Transcription and Patterning |
| Discussion Leader: Susan Mango (Harvard University, USA) |
7:30 pm - 7:50 pm | Marja Timmermans (Cold Spring Harbor Laboratory, USA) "Small RNAs as Morphogen-Like Signals in the Patterning of Leaves" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:10 pm | Isabel Guerreiro (University of Geneva, Switzerland) "The Evolution of Hox Gene Regulation in Vertebrates" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:35 pm | Sharon Dent (The University of Texas, M.D. Anderson Cancer Center, USA) "USPs in Development and Disease" |
8:35 pm - 8:45 pm | Discussion |
8:45 pm - 9:05 pm | Michael Levine (Princeton University, USA) "Visualization and Evolution of Developmental Enhancers" |
9:05 pm - 9:15 pm | Discussion |
9:15 pm - 9:30 pm | Closing Remarks |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |