Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: 50 Years of Positional Information
7:40 pm - 7:45 pm
Introduction by Discussion Leader: Positional Information in 2019
7:45 pm - 8:10 pm
"50(+1) Years of the French Flag Problem"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Boundary Formation by Mobile Small RNAs"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Mechanical Forces and Epithelial Morphogenesis"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Orchestration of Cellular Spatial Information and Differentiation: ERK Signaling in Germ Cell Development"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Human Time vs Mouse Time in the Segmentation Clock"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Out with the Old, in with the New: ERK Coordinates Cell Fate Rewiring in Early Development"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Studying Human Cerebral Cortex Development in Health and Disease with Stem Cell Systems"
11:10 am - 11:20 am
Discussion
11:20 am - 11:35 am
"An Enriched Network Motif Family Regulates Multistep Cell Fate Transitions with Restricted Reversibility"
11:35 am - 11:40 am
Discussion
11:40 am - 11:55 am
"Uncovering the Developmental Rules for Kidney Duct Morphogenesis by Programming Mesenchymal Remodeling in Space and Time"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Towards In Vitro Precision In Vivo
7:30 pm - 7:50 pm
"How Tissue Geometry and Mechanics Regulate Signaling During Gastrulation"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Dynamics of Cell Polarity Signaling in Early Development"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Recreating Human Kidney Tissue from Stem Cells: How Well Are We Mimicking What We Know of Normal Development?"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
"Engineering of Multicellular Organization and Morphogenesis of Human Pluripotent Stem Cells Using Automated Prediction"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Identity and Robustness in the Era of Single-Cell 'Omics
9:00 am - 9:20 am
"Epigenetic Recovery from Transgenerational RNA Silencing in the C. elegans Germline"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Cellular Biographies: Reconstructing Developmental Trajectories and Lineages"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Single-Cell Transcriptomics of the Acoel Hofstenia Reveals the Evolution of Bilaterian Cell Types and Stem Cell Regulation"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Stochastic Regulation of G1 Duration Controls Terminal Cell Differentiation and Cell Cycle Exit"
11:10 am - 11:20 am
Discussion
11:20 am - 11:35 am
"Single Cell Transcriptomics Reveals Spatial and Temporal Dynamics of Gene Expression in the Developing Mouse Spinal Cord"
11:35 am - 11:40 am
Discussion
11:40 am - 11:55 am
"Single-Cell Analysis of Cell Fate Plasticity During Regeneration in Drosophila "
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Chromatin and Epigenetic Influences on Cell Identity
7:30 pm - 7:50 pm
"Evolution and Function of Vertebrate-Specific Atypical Notch Ligand"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Hox Binding Logic During Spinal Cord Patterning"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Reprogramming of Cell Fate and Function in the Context of Chromatin"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
"The Transcriptional Environment in the Nucleus Becomes Increasingly Heterogeneous as Embryonic Development Progresses"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Dynamic Imaging and Imaging Dynamics
9:00 am - 9:20 am
"The Root Endodermis: An Independent Way of Building a Polarised Epithelium"
9:20 am - 9:30 am
Discussion
9:30 am - 9:45 am
"Tracing the Origin of Adult Intestinal Stem Cells"
9:45 am - 9:50 am
Discussion
9:50 am - 10:05 am
"Building the Best Barrier: How Cell Competition Shapes Epidermal Morphogenesis"
10:05 am - 10:10 am
Discussion
10:10 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Real-Time Developmental Biology with a Shareable Microscopy Platform"
11:05 am - 11:15 am
Discussion
11:15 am - 11:30 am
"Dynamics of the SHR-SCR Network Controlling Asymmetric Cell Division"
11:30 am - 11:35 am
Discussion
11:35 am - 11:50 am
"Expanding the Fluorescent Reporter Toolkit in Mouse Using a Novel CRISPR-Mediated Genome Editing Method"
11:50 am - 11:55 am
Discussion
11:55 am - 12:00 pm
General Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
7:30 pm - 7:55 pm
"BMP Morphogen Gradient Formation and Interpretation (Positional Information Session Redux)"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Obligate Endosymbiosis in Ants Reveals Developmental Steps to Major Evolutionary Transitions"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Patterning Morphogenesis via the Planar Cell Polarity Pathway"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
"Multi-Scale Coordination of Planar Cell Polarity in Planarians"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Metabolism and Growth Control
9:00 am - 9:20 am
"The Role of the Dilp8/Lgr3 Pathway in Adjusting Final Organ Size and Minimizing Developmental Noise"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Cell Competition and the Regulation of Growth in the Early Mouse Embryo"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Structural Basis for Cholesterol Transport-Like Activity of the Hedgehog Receptor Patched"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Metabolic Adaptation in Cavefish"
11:10 am - 11:20 am
Discussion
11:20 am - 11:35 am
"Coordinating Organ Growth and Patterning in the Developing Larvae "
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"The Energetic Costs of Early Development"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"A Single-Cell Reconstruction of Planarian Regeneration"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Developmental Robustness in Noisy Systems
7:30 pm - 7:50 pm
"How Fluctuations in a Transcription Factor Initiate Cell Patterning in Arabidopsis Sepals"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Precision in a Rush: Cell Fate Decisions from Time Dependent Data"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Inferring Context-Dependent Transcriptional Regulation from Cell-Lineage Data"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
"Contributions of Fate Plasticity and Mechanics to Vein Patterning in the Drosophila Wing"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure