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Developmental Biology (GRS)

Gordon Research Seminar

Genesis, Maintenance and Repair: Exploring the Principles of Building an Organism

June 24 - 25, 2023

Chairs

and

Mount Holyoke College

50 College Street

South Hadley, Massachusetts, United States

Venue and Travel Information

Conference Description

The Developmental Biology GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

The 2023 seminar will emphasize on the emergence of global approaches in developmental biology and how state-of-the-art techniques such as single-cell 'omics, in toto live imaging and their associated computational tools are allowing the study of developmental processes at an unprecedented scale, and revealing new insights into principles that build an organism. Topics will bring together speakers across multiple disciplines within developmental biology including: stem cells & regeneration, signaling across scales, mechanical morphogenesis, single cell dynamics, and niches and environmental influence on development.

Related Meeting

This GRS will be held in conjunction with the "Developmental Biology" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm	Keynote Session: Environmental Factors in Development Discussion Leader:
3:45 pm - 3:50 pm	Introduction by Discussion Leader
3:50 pm - 4:20 pm	"Environmental Factors that Mediate or Disrupt Mammalian Embryogenesis"
4:20 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Growth, Differentiation and Regeneration Discussion Leaders: and
7:30 pm - 8:00 pm	"Elucidating the Mechanisms Critical for Pluripotency and Regeneration in Planarians"
8:00 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"Role of FoxA2 in Hedgehog Signaling Termination in Zebrafish Spinal Cord"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"Sensory Control of Blood Progenitor Redox Balance in Drosophila"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	"Dynamic Readout of the Hh Gradient in the Drosophila Wing Disc reveals Pattern-Specific Tradeoffs between Robustness and Precision"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Dynamic Supracellular Actomyosin Network Architectures are Disrupted in SPCA1 Mutants During Cranial Mouse Neural Tube Closure"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Patterning and Morphogenesis Discussion Leader:
9:00 am - 9:15 am	"Stay FLAT or BUCKLE? The Causes and Consequences of Mechanical Buckling in Arabidopsis Sepals"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	"Visceral Organ Morphogenesis via Calcium-Patterned Muscle Constrictions"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	"The Cranial Mesenchyme as a Potential Driver of Neural Tube Closure"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Downregulation of Extraembryonic Tension Controls Body Axis Formation in Avian Embryos"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	"Molecular and Cellular Mechanisms Underlying Myoblast Fusion during Mouse Skeletal Muscle Development"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	"Cellular prestress of ECM fibers regulates nonlinear morphogenetic mechanics in the looping intestine"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Genetic and Epigenetic Regulation of Cell Fate Discussion Leader:
1:30 pm - 1:45 pm	"Interrogating the Lineage Trajectories and Regulators Governing Human Stem Cell-Derived Beta Cell Differentiation"
1:45 pm - 1:50 pm	Discussion
1:50 pm - 2:05 pm	"Molecular Evolution in Oskar Protein Function in Drosophila"
2:05 pm - 2:10 pm	Discussion
2:10 pm - 2:25 pm	"Developing Fast: Uncoupling of Transcriptional and Morphological Changes in Marsupial Organogenesis"
2:25 pm - 2:30 pm	Discussion
2:30 pm - 3:00 pm	Evaluation Period Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm	Seminar Concludes

Contributors

Research reported in this publication was supported by the Eunice Kennedy Shriver National Institute of Child Health & Human Development of the National Institutes of Health under Award Number R13HD112177. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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