| Saturday |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Collective Cell Migration in Health and Disease |
| What holds motile epithelial cells at compartment boundaries and how do metastasizing
cells resist these constraints? |
| Discussion Leader: Ritankar Majumdar (National Cancer Institute, NIH, USA) |
| 3:45 pm - 4:20 pm | Keynote: Andrew Ewald (Johns Hopkins University School of Medicine, USA)
"Mechanisms of Escape from Epithelial Tissues" |
| 4:20 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Experimental Paradigms in Cell Migration |
| Unity in Diversity - Insights into the strategies utilized by model systems for cell migration and chemotaxis. |
| Discussion Leaders: Richard Gomer (Texas A&M University, USA) and Luke Tweedy (Beatson Institute for Cancer Research, United Kingdom) |
| 7:30 pm - 7:45 pm | Florian Gaertner (LMU Munich, Germany)
"Single Cell Tracking Identifies Migration as a Novel Platelet Function Facilitating Thrombus Reorganization" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Maria Kotini (University College London, United Kingdom)
"Gap Junctions Control Neural Crest Directional Migration" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Rachel Lee (University of Maryland, USA)
"Quantifying Collective Cell Migration During Cancer Progression" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Netra Meena (National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA)
"A Novel Secreted Protein that Promotes Cell Motility, Chemotaxis, and Cell-Cell Interaction" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Madeleine Oudin (Massachusetts Institute of Technology, USA)
"Mena at the Nexus of Chemotaxis and Haptotaxis During Tumor Progression" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Bettina Weigelin (Radboud University Nijmegen Medical Center, The Netherlands)
"Guided Cancer Cell Invasion Along Tissue Highways" |
| 9:25 pm - 9:30 pm | Discussion |
| Sunday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Physical Basis of Cell Migration |
| How the marriage of Physics, Mathematics and Biology has led to new perspectives on old biological
problems. |
| Discussion Leaders: Jason Haugh (North Carolina State University, USA) and Assaf Zaritsky (University of Texas Southwestern Medical Center, USA) |
| 9:00 am - 9:35 am | Keynote: Xavier Trepat (Institut de Bioenginyeria de Catalunya, Spain)
"Control of Collective Cell Migration by Intracellular Adhesion complexes" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 9:55 am | Maté Biro (Centenary Institute of Cancer Medicine and Cell Biology, Australia)
"Disentangling Plasticity: Distinct Modes of Leukocyte Migration Controlled by Actin Nucleators" |
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | Laurel Hind (University of Pennsylvania, USA)
"Force Generation of Migrating Macrophages on Compliant Surfaces" |
| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 10:35 am | Andrew Loza (Washington University in St. Louis School of Medicine, USA)
"Cell Density Modulates Collective Migration Through Changes in Actomyosin Contractility" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Erik Welf (University of Texas Southwestern Medical Center, USA)
"Strategies for Quantifying Melanoma Morphodynamic Plasticity" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Mentorship Component: Ask the PI |
| Are model organisms the gold standard in migration
research? What is the best way to prepare for a panel interview? How do we fix
a broken publication process? It’s time to hit our team with all your burning
questions! |
| Discussion Leader: Shirin Pocha (University of California, Santa Barbara, USA) |
| 1:30 pm - 2:30 pm | Panel Discussion |
|
- Andrew Ewald (Johns Hopkins University School of Medicine, USA)
- Richard Gomer (Texas A&M University, USA)
- Jason Haugh (North Carolina State University, USA)
- Denise Montell (University of California, Santa Barbara, USA)
- Carole Parent (Center for Cancer Research, National Cancer Institute, NIH, USA)
- Xavier Trepat (Institut de Bioenginyeria de Catalunya, Spain)
|
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
