SUNDAY |
4:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | NEW WAYS OF THINKING |
| Discussion Leaders: Thomas Kissel (University of Marburg) & Alexander Kabanov (University of Nebraska Medical Center) |
7:30 pm - 8:20 pm | Napoleone Ferrara (Genentech)
"Targeting VEGF for cancer and age-related macular degeneration" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 9:20 pm | David A. Tirrell (California Institute of Technology)
"New Ways of Thinking about Proteins" |
9:20 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | NANO-ENGINEERED DELIVERY |
| Discussion Leader: Vladimir Torchilin (Northeastern University) |
9:00 am - 9:40 am | Pat Stayton (University of Washington)
"Smart Polymeric Delivery Systems" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:25 am | Robert Prud'homme (Princeton University)
"Nanoparticle formation by flash nano-precipitation using block copolymer directed self-assembly" |
10:25 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:40 am | Alexander Kabanov (University of Nebraska Medical Center)
"Charge-driven self-assembly of nano-formulations" |
11:40 am - 11:45 am | Discussion |
11:45 am - 12:25 pm | Rainer Haag (University of Berlin, Germany)
"Functional dendritic architectures for DNA and drug delivery" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session (presenters available) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | GENE DELIVERY |
| Discussion Leader: Alexander Kabanov (University of Nebraska Medical Center) |
7:30 pm - 8:10 pm | Ernst Wagner (University of Munich, Germany)
"Targeting of non-viral vectors for cancer gene therapy" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:55 pm | Vladimir Torchilin (Northeastern University, Boston)
"Multifunctional pharmaceutical nanocarriers for cancer therapy and imaging" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:25 pm | Suzie Pun (University of Washington)
"Non-viral nucleic acid delivery to neurons" |
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | DELIVERY OF siRNA |
| Discussion Leader: Ernst Wagner (University of Munich, Germany) |
9:00 am - 9:40 am | Judy Lieberman (Harvard University)
"The silent treatment: Delivering RNA interference" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:25 am | John J. Rossi (Beckman Research Institute of the City of Hope, Duarte)
"Delivering therapeutic shRNAs and siRNAs to target cells" |
10:25 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:40 am | Mano Manoharan (Alnylam, Pharmaceuticals, Cambridge)
"siRNA delivery in vivo" |
11:40 am - 11:45 am | Discussion |
11:45 am - 12:25 pm | Martyn Davies (University of Nottingham, UK)
"Studies on biomolecular interactions of DNA and RNA for therapeutic target identification and delivery systems at the molecular level" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session (presenters available) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | NANO SCIENCES AND MEDICINE |
| Discussion Leader: Martyn Davies (University of Nottingham, UK) |
7:30 pm - 8:10 pm | Patrick Couvreur (University of Paris, France)
"Nano-devices and therapeutic innovation" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:45 pm | James R. Heath (California Institute of Technology)
"Nanosystems biology for in vitro and in vivo diagnostics" |
8:45 pm - 9:00 pm | Discussion |
9:00 pm - 9:25 pm | Christine Allen (University of Toronto)
"Imaging as a tool for the design and development of liposomal drug formulations" |
9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | ANTIBODIES AND PROTEINS |
| Discussion Leader: Henry Kopecek (University of Utah) |
9:00 am - 9:40 am | Peter Senter (Seattle Genetics)
"Towards optimizing antibody-drug conjugates for cancer therapy" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:25 am | James D. Marks (University of California, San Francisco)
"Tumor cell binding and internalizing antibodies from phage libraries" |
10:25 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:40 am | Jan E. Schnitzer (Sidney Kimmel Cancer Center, San Diego)
"Proteomic mapping of endothelial caveolae in vivo to improve antibody penetration, imaging and therapy of solid tumors" |
11:40 am - 11:45 am | Discussion |
11:45 am - 12:25 pm | William Banks (Saint-Louis University)
"Principles of peptide and protein transport across the blood-brain barrier" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 8:00 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
8:00 pm - 9:30 pm | RECENT DEVELOPMENTS IN DRUG DELIVERY |
| Discussion Leader: Thomas Kissel (University of Marburg) |
8:00 pm - 8:25 pm | Ronit Satchi-Fainaro (University of Tel Aviv, Israel)
"Targeting tumor vasculature with polymer conjugates of angiogenesis inhibitors" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:55 pm | Dong Wang (University of Nebraska Medical Center)
"Novel drug delivery strategies for improved treatment of musculoskeletal diseases" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:25 pm | Theresa Reinecke (University of Cincinnati)
"Design of Glycopolymers for ODN decoy delivery" |
9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | TARGETING |
| Discussion Leader: Peter Senter (Seattle Genetics) |
9:00 am - 9:40 am | Phil Low (Purdue University)
"Receptor-Targeted therapies for cancer and inflammatory diseases" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:25 am | Kit S. Lam (University of California, Davis)
"The use of one-bead one-compound combinational libraries to discover cell surface targeting agents" |
10:25 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:40 am | Charles B. Grissom (University of Utah)
"Cancer drug targeting and molecular imaging of tumors with cobalamin" |
11:40 am - 11:45 am | Discussion |
11:45 am - 12:25 pm | Phil. E. Thorpe (University of Texas, Dallas)
"Antibodies to Phosphatidylserin for targeting tumor blood vessels and viruses" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CARRIERS |
| Discussion Leader: David A. Scheinberg |
7:30 pm - 8:10 pm | Wim Hennink (University of Utrecht, The Netherlands)
"Biodegradable dextran microspheres for the controlled release of proteins" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:55 pm | Frank Szoka (University of California, San Francisco)
"pH responsive Drug & Gene Carriers: Mechanisms, advantages, shortcomings" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:25 pm | David Putnam (Cornell University)
"Mapping the structural parameter space of non-viral nucleic acid delivery vectors" |
9:25 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |