SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Vascular delivery, targets and barriers |
| Discussion Leader: Silvia Muro (University of Maryland) |
7:40 pm - 8:10 pm | Jan Schnitzer (Proteogenomics Research Institute for Systems Medicine)
"Vascular targeting via caveolar pathways" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | Grietje Molema (University of Groningen)
"Carriers for anti-inflammatory vascular interventions - therapeutics and tools for endothelial biology" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Shad Thaxton (Northwestern University)
"Biomimetric High Density Lipoprotein (HDL) Nanoparticles for Nucleic Acid Delivery" |
9:20 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Translational studies, clinical trials and combination therapies |
| Discussion Leader: David Scheinberg (Memorial Sloan-Kettering Cancer Center) |
9:00 am - 9:30 am | Lawrence Mayer (Celator Pharmaceuticals)
"Challenges and Opportunities for Developing Drug Carrier-Based Combination Chemotherapy Formulations" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Ruth Duncan (University of Cardiff)
"Bioresponsive/biodegradable polymer therapeutics for cancer and tissue repair" |
10:15 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Group Photo / Coffee Break |
11:00 am - 11:30 am | Paula Hammond (Massachusetts Institute of Technology)
"Nanodevices for cellular drug delivery and controlled release" |
11:30 am - 11:45 am | Discussion |
11:45 am - 12:15 pm | Sonke Svenson (Cerulean Pharma Inc)
"Nanopharmaceuticals in Drug Delivery: Phase 2 Candidate Camptothecin-CDP (CRLX101) and Preclinical Candidate siRNA-PNP" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Local, pulmonary, GI and CNS delivery: barriers, transporters, devices |
| Discussion Leader: Patrick Stayton (University of Washington) |
7:30 pm - 8:00 pm | Krystof Bankiewicz (University of California San Francisco)
"Delivery of drugs, genes and imaging probes to the CNS" |
8:00 pm - 8:15 pm | Discussion |
8:15 pm - 8:45 pm | Randy Mrsny (University of Bath)
"Permeation of barriers for GI and pulmonary drug delivery" |
8:45 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Vikash Chauhan (Harvard Medical School)
"Overcoming tumor delivery barriers" |
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Emerging technologies, materials, carriers and mechanisms |
| Discussion Leader: Sasha Kabanov (University of Nebraska) |
9:00 am - 9:30 am | Omid Farokhzad (Harvard University)
"New generations of targeted nanocarriers" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Gabriel Lopez (University of Texas MD Anderson Cancer Center)
"Monocytes and Macrophages: friends or foes... or both"
|
10:15 am - 10:30 am | Discussion |
10:30 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Debra Auguste (Harvard University)
"A Personalized Approach to Targeting Metastatic Breast Cancers" |
11:15 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Efrosini Kokkoli (University of Minnesota)
"Peptide-targeted nanodevices for drug delivery" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Tyrone Porter (Boston University)
"Ultrasound-assisted drug delivery systems" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Natural carriers (cells, proteins and peptides) |
| Discussion Leaders: Philip Low (Purdue University) and William Zamboni (Univesrity of North Carolina) |
7:30 pm - 8:00 pm | Catherine Bollard (Baylor College of Medicine)
"Cellular therapies: stem cells, modulation of immune response" |
8:00 pm - 8:15 pm | Discussion |
8:15 pm - 8:45 pm | Mauro Magnani (University of Urbino)
"Drug delivery by red blood cells" |
8:45 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Jennifer R. Cochran (Stanford University)
"Engineered protein-based targeted therapeutics and probes" |
9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Carriers for delivery of biologicals including vaccines and antigens |
| Discussion Leader: Jennifer Cochran (Stanford University) |
9:00 am - 9:30 am | Nathalie Garcon (Global Adjuvant Center for Vaccines at GlaxoSmithKline)
"Design of better vaccines: translational perspectives" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Tarek Fahmy (Yale University)
"Carriers for drug delivery antigens and probes to immune system" |
10:15 am - 10:30 am | Discussion |
10:30 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Derek O'Hagan (Novartis Vaccines and Diagnostics)
"New Generation of Vaccine Adjuvants" |
11:15 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Sam Lai (University of North Carolina)
"PEG coatings and their interactions with immune cells and antibodies" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Karyn O'Neil (Centyrex, Johnson & Johnson)
"Exploiting the Biophysical Properties of Centyrins for Novel Therapeutics"
|
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session II |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Latest news and young voices |
| Discussion Leaders: Heather D. Maynard (University of California Los Angeles) and Paul A. Burke (Burke Bioventures LLC) |
| TBA (six short 10 minute talks with 5 minutes discussion selected from the posters) |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Intracellular delivery, trafficking and cellular barriers |
| Discussion Leader: Jan Schnitzer (Proteogenomics Research Institute for Systems Medicine) |
9:00 am - 9:50 am | Keynote Speaker: Chad Mirkin (Northwestern University)
"Emerging materials for intracellular delivery" |
9:50 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Renata Pasqualini and Wadih Arap (University of Texas MD Anderson Cancer Center)
"Decoding vascular zip codes for treatment of human diseases" |
10:40 am - 10:55 am | Discussion |
10:55 am - 11:10 am | Coffee Break |
11:10 am - 11:40 am | Hamid Ghandehari (University of Utah)
"Nanocarriers for intracellular and transcellular drug delivery"
|
11:40 am - 11:55 am | Discussion |
11:55 am - 12:20 pm | Silvia Muro (University of Maryland)
"Endosomal delivery via adhesion molecules" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session II |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Biological response to delivered drugs and genes |
| Discussion Leader: Leaf Huang (University of North Carolina) |
7:30 pm - 8:00 pm | William Zamboni (University of North Carolina)
"Profiling the biological factors modulating drug delivery in preclinical animal models and in patients" |
8:00 pm - 8:15 pm | Discussion |
8:15 pm - 8:45 pm | Carol H. Miao (Seattle Children's Hopsital)
"Modulation of non-viral gene therapy for hemophilia" |
8:45 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Joy Yu (Genentech)
"Crossing the blood-brain barrier: transcytosis of a therapeutic antibody"
|
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |