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Drug Carriers in Medicine and Biology (GRS)

Gordon-Merck Research Seminar

Molecular and Cellular Engineering Advances in Drug Targeting

August 16 - 17, 2014
Chairs and
Waterville Valley
56 Packard's Road
Waterville Valley, New Hampshire, United States
 Venue and Travel Information

Conference Description

The inaugural 2014 Gordon Research Seminar on "Drug Carriers in Medicine and Biology" is a unique forum for graduate students, post-docs, and other drug delivery scientists in the fields of cancer, immunology, and structural biology to gather, network, and build relationships with investigators from across the globe. The Drug Carriers GRS aims to bring together researchers from both academia and the biotech/pharmaceutical industries to exchange late-breaking research and cutting-edge ideas in an informal setting, designed to promote discussion and feedback between peers and select senior investigators.

The focus of this meeting is on advances in antibody and protein-based drug carrier engineering, synthetic nanosystems as tissue-specific delivery agents, and cell-based therapeutics for use in cancer, immune, infectious, and neurological disease. The overarching theme will focus on understanding the biological fate of engineered drug carriers as well as the design considerations, hurdles, and opportunities of utilizing drug carriers to treat human disease.

Related Meeting

This GRC will be held in conjunction with the "Drug Carriers in Medicine and Biology" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

SATURDAY
1:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session
Discussion Leaders: Jonathan Sockolosky (Stanford) and Erica Schlesinger (UCSF)
4:15 pm - 4:30 pmPeter Senter (Seattle Genetics)
"Empowered Antibodies for Cancer Therapy"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmAntibodies, Scaffolds, and Designer Proteins as Drugs and Carriers
Discussion Leaders: Peter Senter (Seattle Genetics) and Xiqiu Liu (Grenoble INP)
7:30 pm - 7:50 pmEva Strauch (University of Washington)
"Custom Protein Binding: Computational Design to Address Protein Engineering Challenges"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmKunwoo Lee (UC Berkeley)
"In Vivo Delivery of Transcription Factors with Multifunctional Oligonucleotides"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmLavanya Peddada (Janssen Pharmaceuticals)
"Applications of Centyrin Platform in Drug Delivery and Therapy"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmMinyoung Park (University of Toronto)
"Development of a Targeted Intracellular Delivery Platform for Protein Therapeutics"
9:20 pm - 9:30 pmDiscussion
SUNDAY
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amPolymer, Lipids, and Synthetic Delivery Vehicles
Discussion Leaders: Paula Hammond (MIT) and Caitlin Decker (UCLA)
9:00 am - 9:20 amYoung Lim (Texas A&M University)
"Development of Polyphosphoester-Based Polymeric Nanoparticles as Delivery Carriers for Silver-Based Antimicrobial Agents for Treatment of Infectious Diseases"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amKatherine Moga (UNC Chapel Hill)
"Transdermal Delivery of Therapeutic Cargo via Highly Reproducible PRINT Microneedle Devices"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amRong Tong (MIT)
"Photoswitchable Nanoparticles for In Vivo Chemotherapy"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amJanuka Budhathoki-Uprety (Memorial Sloan-Kettering)
"Helical Polycarbodiimide Encapsulation of Fluorescent Carbon Nanotubes Enables Inter-Nanotube FRET Modulation and Subcellular Targeting"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session II
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmCell-Based Therapeutics in Cancer and Immunology
Discussion Leaders: Ruth Duncan (Cardiff University) and Gaurav Sahay (MIT)
1:30 pm - 1:50 pmAileen Li (Harvard University)
"Injectable and Spontaneously-Assembling Inorganic Scaffolds for In Vivo Immune Cell Recruitment and Modulation"
1:50 pm - 2:00 pmDiscussion
2:00 pm - 2:20 pmLi Tang (MIT)
"Engineering T Lymphocytes with Protein Nanogels for Cancer Immunotherapy"
2:20 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

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Conference History Drug Carriers in Medicine and Biology
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