Saturday |
2:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Keynote Session: Application of Systems Pharmacology Principles to the Development of nal-IRI, Liposomal Irinotecan |
| Discussion Leader: James Kaczmarek (Massachusetts Institute of Technology, USA) |
3:45 pm - 4:20 pm | Jonathan Fitzgerald (Merrimack, USA) "Application of Systems Pharmacology Principles to the Development of nal-IRI, Liposomal Irinotecan" |
4:20 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Nanoparticle Preparation, Characterization, and Scale Up |
| Discussion Leader: Santiago Correa-Echavarria (Massachusetts Institute of Technology, USA) |
7:30 pm - 7:50 pm | Ioana Aanei (University of California, Berkeley, USA) "Viral Capsids as Versatile Scaffolds for Drug Delivery Applications" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Erin Wilson (University of North Carolina at Chapel Hill, USA) "Engineering PRINT® Dry Powders for Pulmonary Drug Delivery" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Leo Chou (Dana-Farber Cancer Institute / Harvard Medical School, USA) "Building an RNA-Extruding Nanofactory Within DNA Origami Nanocapsule" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Brett Geiger (Massachusetts Institute of Technology, USA) "Design Considerations and Strategies for Cartilage-Penetrating Nanoparticles" |
9:20 pm - 9:30 pm | Discussion |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Biophysical and Biochemical Interactions of Nanoparticles with Cells |
| Discussion Leader: Armando Hernandez-Garcia (Northwestern University, USA) |
9:00 am - 9:20 am | Aaron Anselmo (Massachusetts Institute of Technology, USA) "Hitchhiking Nanoparticles on Red Blood Cells: A Stealth Approach for Targeted Nanoparticle Delivery" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Siddharth Patel (Oregon State University, USA) "Mechanisms of Intracellular Trafficking and Endosomal Escape of Nanoparticle-mRNA Therapeutics" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Lorena Simon Gracia (University of Tartu, Estonia) "pH-Sensitive Polymersomes Targeted with CendR Peptides for Treatment of Peritoneal Carcinomatosis" |
10:20 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Erik Munsell (University of Delaware, USA) "Histone-Targeted Gene Delivery Carriers for Bone Regeneration" |
10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Drug Delivery In Vivo |
| Discussion Leader: Shrey Sindhwani (University of Toronto, Canada) |
1:30 pm - 1:50 pm | Chintan Kapadia (University of North Carolina at Chapel Hill, USA) "Engineering PRINT® Nanoparticle Subunit Vaccine to Induce Antitumor Immune Response" |
1:50 pm - 2:00 pm | Discussion |
2:00 pm - 2:20 pm | Emily Wyatt (California Institute of Technology, USA) "Design of Targeted Nanoparticle Therapeutics for Treating Intracranial Disease and Improved Preclinical Models" |
2:20 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |