Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Historical Perspectives and Future Trends in Elastin Research
Discussion Leaders: Clair Baldock (University of Manchester, United Kingdom) and Stylianos Zafeirios Karoulias (Icahn School of Medicine at Mount Sinai, USA)
3:45 pm - 4:15 pm
Anthony Weiss (The University of Sydney, Australia)
"Historical Perspectives and Future Trends in Elastin Research"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Structure, Assembly and Interactions of Elastin and Elastin-Associated Proteins
Discussion Leaders: Miguel A. Ortega (University of Alcala, Spain) and Rong-Mo Zhang (McGill University, Canada)
7:30 pm - 7:45 pm
Yasmene Alanazi (The University of Manchester, United Kingdom)
"The Role of Latent TGFβ Binding Protein-4 in Elastic Fibre Assembly and Disruption in Urban-Rifkin-Davis Syndrome"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Allison Arai (University of Maryland School of Medicine, USA)
"Multiple Rare Inherited Human LRP1 Variants Associated with Aortic Disease Impair LRP1 Processing and/or Maturation In Vitro "
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Katrin Hildebrandt (University of Cologne, Germany)
"Microenvironmental Regulation of Muscle Homeostasis by Supramolecular Collagen VI and Fibrillin-2 Networks"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Nandaraj Taye (Icahn School of Medicine at Mount Sinai, USA)
"Loss of ADAMTSL2 Restricts Skeletal Muscle Cell Differentiation"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Bartosz Pilecki (University of Southern Denmark, Denmark)
"Microfibrillar-Associated Protein 4 Promotes Retinal Cell Activation"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Muthu Lakshmi Muthu (McGill University, Canada)
"Regulation of Adipogenesis and Adipose Tissue Homeostasis by Fibrillin-1"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Novel Approaches in Health and Disease: Implications for Tissue Engineering and Regenerative Medicine
Discussion Leaders: Allison Arai (University of Maryland School of Medicine, USA) and Muthu Lakshmi Muthu (McGill University, Canada)
9:00 am - 9:15 am
Alycia Berman (Purdue University, USA)
"Assessment of Murine Aneurysm Expansion and Intraluminal Thrombus Formation by Standard and Volumetric Ultrasound"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Caitlin Bowen (Johns Hopkins University School of Medicine, USA)
"Mechanistic and Therapeutic Interrogation of Novel Mouse Models of Vascular Ehlers-Danlos Syndrome"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Shataakshi Dahal (Lerner Research Institute, Cleveland Clinic, USA)
"Quantitative Morphometry Assessment of Elastic Fibers in Pelvic Organ Prolapse "
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Sergio Acosta (University of Valladolid, Spain)
"Elastin-Like Recombinamers and Antimicrobial Peptides: Self-Assembly Dynamics and Antimicrobial Properties of Hybrid Polypeptides"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Sana Nasim (Florida International University, USA)
"Aortic Valve Elastogenesis Requires Neural Crest Derived Valvular Interstitial Cells"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Daniela Valdez-Jasso (University of California, San Diego, USA)
"Contribution of Fibrillar-Matrix Remodeling to Biaxial Mechanics of Pulmonary Arteries in Hypertension"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Making the Best of My Scientific Career
Discussion Leaders: Nandaraj Taye (Icahn School of Medicine at Mount Sinai, USA) and Daniela Valdez-Jasso (University of California, San Diego, USA)
1:30 pm - 2:30 pm
Panel Discussion
Making the Best of My Scientific Career
Clair Baldock (University of Manchester, United Kingdom)
Dirk Hubmacher (Icahn School of Medicine at Mount Sinai, USA)
Beth Kozel (National Heart, Lung, and Blood Institute, NIH, USA)
Robert Mecham (Washington University School of Medicine, USA)
Elaine Davis (McGill University, Canada)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes