| Saturday |
| 1:30 pm - 4:30 pm | Arrival and Check-in |
| 3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:15 pm - 4:00 pm | Keynote Session: Endothelial Collective Cell Migration |
| Discussion Leader: Victoria Bautch (The University of North Carolina at Chapel Hill, USA) |
| 3:15 pm - 3:55 pm | Karen Hirschi (Yale School of Medicine, USA)
"How Endothelial Cells Make Blood" |
| 3:55 pm - 4:00 pm | Discussion |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | Blood Vessels in Disease and Wound Healing |
| Discussion Leader: Christopher Hughes (University of California, Irvine, USA) |
| 5:30 pm - 5:45 pm | James McCann (University of North Carolina at Chapel Hill, USA)
"A Mouse Model for Tracking and Auditing Endothelial Cell-Derived Extracellular Vesicles in Health and Disease" |
| 5:45 pm - 5:50 pm | Discussion |
| 5:50 pm - 6:05 pm | Emma Watson (Walter and Eliza Hall Institute of Medical Research, Australia)
"Pro-Survival Protein MCL1 Is Essential for Endothelial Cell Survival During Angiogenesis" |
| 6:05 pm - 6:10 pm | Discussion |
| 6:10 pm - 6:25 pm | Kerrie Collins (University of Illinois at Chicago, USA)
"Septins Regulate Endothelial Cell Podosome Formation and Matrix Degradation" |
| 6:25 pm - 6:30 pm | Discussion |
| 6:30 pm - 6:45 pm | Lilian Schimmel (Sanquin Research, The Netherlands)
"The Endothelium Actively Prevents Local Vascular Leakage During Leukocyte Extravsation" |
| 6:45 pm - 6:50 pm | Discussion |
| 6:50 pm - 7:05 pm | Roberto Villasenor (Roche Innovation Center Basel, Switzerland)
"Defining the Endocytic Phenotype of Endothelial Cells at the Blood-Brain Barrier" |
| 7:05 pm - 7:10 pm | Discussion |
| 7:10 pm - 7:25 pm | Anne Karine Lagendijk (Institute for Molecular Biology, University of Queensland, Australia)
"Live-Imaging of Tension Through Zebrafish VE-Cadherin Uncovers Mechanical Contributions in Artery Maturation and Cavernous Malformation" |
| 7:25 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| Sunday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Mentorship Component: Career Panel / Mechanisms of Blood Vessel Patterning and Remodeling |
| Discussion Leader: Christiana Ruhrberg (University College London, United Kingdom) |
| 9:00 am - 10:00 am | Panel Discussion |
| "Advice and Guidance from New and Established Academic Investigators as Well as Industry Professionals" |
|
- Victoria Bautch (The University of North Carolina at Chapel Hill, USA)
- Sunday Oladipupo (Lilly Research Laboratories, USA)
- Christiana Ruhrberg (University College London, United Kingdom)
|
| 10:00 am - 10:15 am | Krista Heinolainen (University of Helsinki / Wihuri Research Institute, Finland)
"VEGFR3 Modulates Vascular Permeability by Regulating VEGF/VEGFR2 Signaling" |
| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 10:35 am | Anastasia Lampropoulou (UCL Institute of Ophthalmology, University College London, United Kingdom)
"VEGF165-Induced Vascular Permeability Relies on Both NRP1 and VEGFR2 for ABL-Mediated SRC Activation" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Urs Langen (Max Planck Institute for Molecular Biomedicine, Germany)
"Specialized Endothelial Cell Subpopulations Drive Bone Development via Cell-Matrix Signaling" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Physical Forces in Endothelial Regulation and Morphogenesis |
| Discussion Leader: Mark Kahn (University of Pennsylvania, USA) |
| 1:30 pm - 1:45 pm | Andrew Chang (Red-Horse Lab, Stanford University, USA)
"Artery Growth and Stabilization Is Balanced by Mechanoregulation of Dach1" |
| 1:45 pm - 1:50 pm | Discussion |
| 1:50 pm - 2:05 pm | Drew Glaser (Washington University, USA)
"A Microfluidic Model of the Bone Marrow Endothelium and Microenvironments" |
| 2:05 pm - 2:10 pm | Discussion |
| 2:10 pm - 2:25 pm | Quinton Smith (Johns Hopkins University, USA)
"Elucidating the Effects of Shear and Substrate Rigidity on Human Induced Pluripotent Stem Cells" |
| 2:25 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
