New Discoveries, Mechanisms and Technologies: Advancing the Frontiers of Enzymology

July 15 - 16, 2017

Chair

Waterville Valley

56 Packard's Road

Waterville Valley, New Hampshire, United States

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Enzymes, Coenzymes and Metabolic Pathways is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The 2017 GRS will highlight the latest advances, innovations and new discoveries in enzymology from the fundamentals of determining enzyme function to complex enzyme mechanisms and their roles in cancer and disease. This meeting will also emphasize career development by including a panel of senior and junior leaders from academia, industry, government and beyond, as well as providing multiple opportunities to network in a casual, stimulating environment.

Related Meeting

This GRS will be held in conjunction with the "Enzymes, Coenzymes and Metabolic Pathways" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Keynote Session: Phosphonate Biosynthesis Discussion Leader:
3:45 pm - 4:15 pm	"Phosphonate Biosynthesis: A Treasure Trove for Novel Enzymology"
4:15 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Advances in Fundamentals of Enzymology Discussion Leader:
7:30 pm - 7:50 pm	"Characterization of PqqB: A Protein of Unknown Function Within the Pyrroloquinoline Quinone (PQQ) Biosynthetic Pathway"
7:50 pm - 8:00 pm	Discussion
8:00 pm - 8:20 pm	"Investigating the Regiospecificity of an Unusual Bacterial Acyl-CoA Dehydrogenase"
8:20 pm - 8:30 pm	Discussion
8:30 pm - 8:50 pm	"It's a Trap! Asp/Glu Carboxylate Glycosylation of O-GlcNAc Transferase Triggers Peptide Backbone Reactions"
8:50 pm - 9:00 pm	Discussion
9:00 pm - 9:20 pm	"Destruction and Reformation of an Iron-Sulfur Cluster During Catalysis by Lipoyl Synthase"
9:20 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Innovations and Applications of Enzymology and Metabolic Pathways Discussion Leader:
9:00 am - 9:20 am	"Engineered Caspases with Altered Specificities Enable Identification of Exosites "
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	"Engineering Alternate Radical Rebound Chemistry in Factor Inhibiting HIF (FIH)"
9:50 am - 10:00 am	Discussion
10:00 am - 10:20 am	"Enhanced Catalysis of Glycolytic Pathways by Co-Localization of Enzymes on Nanoparticle Surfaces"
10:20 am - 10:30 am	Discussion
10:30 am - 10:50 am	"The Enzyme Mechanism of a De Novo Designed and Evolved Aldolase"
10:50 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Broadening Horizons in the Scientific Career Landscape This session serves as the career development discussion panel of the conference. The panelists include investigators in academia and industry, as well as experts in non-traditional careers. They will discuss different career paths, offer advice on career development, and answer questions from conference attendees. Discussion Leader:
1:30 pm - 2:30 pm	Panel Discussion Broadening Horizons in the Scientific Career Landscape
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

Contributors

Conference Links

Conference History Enzymes, Coenzymes and Metabolic Pathways

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