| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 4:00 pm - 6:00 pm | Drinks Reception |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | EPIGENETICS AND DISEASE |
| Chair: Ben Tycko, Columbia University, USA
Chair: Gavin Kelsey, The Babraham Institute, Cambridge, UK |
| 7:40 pm | Peter Jones, USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, USA
Mechanisms of DNA methylation in cancer |
| 8:00 pm | Steve Baylin, Comprehensive Cancer Center, Johns Hopkins, Baltimore, USA
Epigenetic mechanisms in cancer |
| 8:25 pm | Tim Bestor, Columbia University, USA
Pathological alterations of genomic methylation patterns |
| 8:50 pm | Maarten van Lohuizen, The Netherlands Cancer Institute, Amsterdam, The Netherlands
Functional analysis of mouse polycomb-repression: implications for development and cancer |
| 9:15 pm | Amar Klar, National Cancer Institute, Frederick, USA
Chromosome translocations provide novel tests of the DNA strand-specific imprinting/segregation model for the development of human psychosis |
| 9:30 pm | End of Session |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:45 am | Conference Photo |
| 9:00 am - 12:30 pm | IMPRINTING |
| 9:00 am | Chair: Phil Avner, Institut Pasteur, Paris, France
Chair: Ueli Grossniklaus, University of Zurich, Switzerland |
| 9:10 am | Michel Georges, University of Liege, Belgium
Imprinting mechanisms in the Callipyge mutation |
| 9:35 am | Anne Ferguson-Smith, Department of Anatomy, University of Cambridge, UK
Genomic imprinting - a hunt for unifying themes |
| 9:55 am | Joern Walter, University of Saarbruecken, Germany
Genome evolution and imprinting mechanisms |
| 10:15 am | Andrew Chess, Whitehead Institute, Boston, USA
Epigenetic control of replication timing |
| 10:30 am | Coffee |
| 10:50 am | Marisa Bartolomei, Philadelphia, USA
Regulation of imprinting at the Igf2/H19 locus |
| 11:15 am | Abed Chaudhury, CSIRO Division of Plant Industry
Imprinting in plant endosperm |
| 11:40 am | Mary Gehring, University of California at Berkeley, USA
Mechanisms of imprinting in Arabidopsis |
| 12:00 pm | Tetsu Kinoshita, National Institute of Genetics, Mishima, Japan
Parent-of-origin-dependent fwa gene expression in the endosperm of arabidopsis |
| 12:30 pm | Lunch |
| 4:00 pm - 6:00 pm | Poster Viewing |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | DNA METHYLATION AND DEVELOPMENT |
| 7:30 pm |
Chair: Richard Chaillet, Children's Hospital of Pittsburgh, USA
Chair: Hiroyuki Sasaki, National Institute Genetics, Mishima, Japan |
| 7:40 pm | Judith Bender, The Johns Hopkins University, Baltimore Campus, USA
DNA methylation of endogenous genes in Arabidopsis |
| 8:00 pm | Richard Meehan, University of Edinburgh, Scotland, UK
Distinct roles for MeCP2 and Kaiso during Xenopus development |
| 8:25 pm | Adrian Bird, Wellcome Trust Centre for Cell Biology, University of Edinburgh, Scotland, UK
Role of methyl binding proteins in gene expression |
| 8:50 pm | Frank Lyko, German Cancer Research Centre, Heidelberg, Germany
DNA methylation in Drosophila |
| 9:10 pm | En Li, Massachusetts General Hospital, Boston, USA
Role of de novo methylation in mouse development |
| 9:30 pm | End of session |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CHROMATIN MECHANISMS |
| 9:00 am | Chair: Jean Finnegan, CSIRO, Plant Industry
Chair: Laura O'Neill , Department of Anatomy, Birmingham University, UK |
| 9:10 am | Andre Nussenzweig, CCR, NCI Bethesda, USA
Phosphorylation marks on histone H2AX: role in genomic stability |
| 9:35 am | Richard Festenstein, Imperial College London, UK
Epigenetic chromatin modifiers |
| 10:00 am | Thomas Jenuwein, Vienna, Austria
Histone methylation in mammalian development |
| 10:25 am | Coffee |
| 10:45 am | Valerio Orlando, Naples, Italy
Gene silencing and genome programming by polycomb proteins |
| 11:05 am | Eric Selker, Eugene, USA
Mechanistic links between epigenetic systems in Neurospora |
| 11:30 am | Steve Jacobsen, Los Angeles, USA
Genetics of histone and DNA methylation in Arabidopsis |
| 11:55 am | Xiaodong Cheng, Emory School of Medicine, Atlanta, USA
Structural analysis of methyltransferases |
| 12:10 pm | Vincent Colot, INRA-CNRS, Paris, France
Epigenetics and genome organization: where junk really matters |
| 12:30 pm | Lunch |
| 4:00 pm - 6:00 pm | Poster Viewing |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | ROLE OF RNA |
| Chair: Jan Kooter, Vrije Universiteit, Amsterdam, The Netherlands |
| 7:40 pm | Marjorie Matzke, Institute of Molecular Biology, Salzburg, Austria
Genetics of silencing by RNA |
| 8:00 pm | Rodolfo Aramayo, Texas A&M University, USA
Meiotic RNA silencing |
| 8:25 pm | Thomas Volpe, Cold Spring Harbor Laboratories, New York, USA
Role of RNAi in heterochromatin gene silencing |
| 8:45 pm | Shiv Grewal, Cold Spring Harbor Laboratories, New York, USA
RNAi and heterochromatin silencing |
| 9:05 pm | Gary Ruvkun, Harvard Medical School, Boston, USA
Role of RNA in C. elegans development |
| 9:30 pm | End of session |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CHROMOSOMAL MECHANISMS |
| Chair: Amar Klar, NCI, NIH
Chair: Vincenzo Pirrotta, University of Geneva, Switzerland |
| 9:10 am | Jeannie Lee, Howard Hughes Medical Institute, Boston, USA
Cis-acting elements of the X-inactivation center |
| 9:35 am | Edith Heard, Curie Institute Paris, France
Chromatin mechanisms involved in X inactivation |
| 9:55 am | Neil Brockdorff, MRC-CSC Imperial College, London, UK
The Eed-Ezh2 PcG complex is required for H3 methylation in X inactivation |
| 10:10 am | Barbara Panning, University of California, San Francisco, USA
Role of mammalian polycomb proteins in X chromosome inactivation. |
| 10:25 am | William Kelly, Emory University, Atlanta, USA
X Chromosome Imprinting in C. elegans |
| 10:40 am | Coffee |
| 11:00 am | Alessia Buscaino, EMBL Heidelberg, Germany
MOF-regulated acetylation of MSL-3 in the Drosophila dosage compensation complex. |
| 11:15 am | Robin Allshire, Wellcome Trust Centre for Cell Biology, Edinburgh, Scotland, UK
Epigenetic regulation of centromere function |
| 11:40 am | Dan Gottschling, Fred Hutchinson Cancer Centre, Seattle, USA
Epigenetic regulation at the telomere |
| 12:05 pm | James Birchler, University of Missouri, Columbia, USA
Repeat induced silencing in Drosophila |
| 12:30 pm | Lunch |
| 4:00 pm - 6:00 pm | Poster Viewing |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | DYNAMIC NUCLEUS |
| Chair: Doug Higgs, Institute of Molecular Medicine
Chair: Chao-Ting Wu, Harvard Medical School, Boston, USA |
| 7:40 pm | Howard Cedar, Hebrew University, Jerusalem, Israel
Epigenetic regulation of DNA replication |
| 8:05 pm | Wendy Bickmore, MRC Human Genetics Unit, Edinburgh, Scotland, UK
Spatial and temporal organization of the mammalian nucleus during differentiation |
| 8:30 pm | Peter Fraser, The Babraham Institute, Cambridge, UK
Epigenetic control of long range chromatin interactions |
| 8:55 pm | Kat Arney, MRC-CSC Imperial College, London, UK
Control of histone modifications in B cell development |
| 9:10 pm | Paul Fransz, University of Amsterdam, The Netherlands
Heterochromatin dynamics and epigenetic gene control in Arabidopsis thaliana |
| 9:30 pm | End of session |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | NATURAL VARIATION, ENVIRONMENT AND EVOLUTION |
| Chair: Emma Whitelaw, University of Sydney, Australia
Chair: Sally Elgin, Washington University, St Louis, USA |
| 9:10 am | Eric Richards, Washington University, St Louis, USA
Mechanisms of epigenetic inheritance in Arabidopsis |
| 9:35 am | Tetsuji Kakutani, National Institute of Genetics, Mishima, Japan
Epigenetic inheritance and transposon control |
| 10:00 am | Vicki Chandler, University of Arizona, Tucson, USA
Evolution of epigenetic mechanisms in Maize |
| 10:25 am | Coffee/Business meeting - election of new Chairs for 2007 |
| 10:45 am | Steve Henikoff, Fred Hutchinson Cancer Center, Seattle, USA
Role of centromeres in evolution |
| 11:10 am | David Symer, National Cancer Institute, Frederick, USA
Genetic andepigenetic instability linked to retrotransposition |
| 11:25 am | Ortrun Mittelsten-Scheid, Friedrich Miescher Institute, Basel, Switzerland
Epigenetic control and ploidy |
| 11:50 am | Caroline Dean, John Innes Centre, Norwich, UK
Epigenetic basis of the cold-induced acceleration of flowering |
| 12:15 pm | Alexander Mazo, Kimmel Cancer Centre, Philadelphia
A novel mechanism for the modulation of heat shock gene expression by a TAC1 chromatin modifying complex |
| 12:30 pm | Lunch |
| 4:00 pm - 6:00 pm | Poster Viewing |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | REPROGRAMMING, CLONING, GERM CELLS, STEM CELLS |
| Chair: Davor Solter, Max Planck Institute of Immunobiology, Freiburg, Germany
Chair: Neil Brockdorff, MRC Clinical Sciences Centre, Hammersmith, London, UK |
| 7:30 pm | Filling in of evaluation forms |
| 7:50 pm | Rudolf Jaenisch, Whitehead Institute Center for Genome Research, MA, USA
Cloning and reprogramming |
| 8:15 pm | Robert Feil, Institute of Molecular Genetics, Montpellier, France
Epigenetic marks in extraembryonic tissues |
| 8:30 pm | Konrad Hochedlinger, Whitehead Institute,
Boston, USA
Reprogramming cancer nuclei |
| 8:45 pm | Hiroyuki Sasaki, National Institute of Genetics, Mishima, Japan
Role of methyltransferases in the germline |
| 9:00 pm | Azim Surani, Wellcome/Cancer Research UK Institute, Cambridge, UK
Molecular determinants of germ cell development |
| 9:25 pm | Laura O'Neill , Davor Solter, Vicki Chandler, Ueli Grossniklaus
Summing up/Raising additional issues |
| 9:30 pm | End of session |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
