SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Epigenetic Phenomena and Mechanisms |
| Discussion Leader: Eric Richards (Boyce Thompson Institute)
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7:40 pm - 7:50 pm | Emma Whitelaw (La Trobe University)
"Nuancing Epigenetics"
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7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:30 pm | Tim Bestor (Columbia University)
"DNA modification and chromatin-based epigenetic systems"
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8:30 pm - 8:45 pm | Discussion |
8:45 pm - 9:15 pm | Yury Chernoff (Georgia Institute of Technology)
"Protein-based inheritance systems"
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9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Establishment of Epigenetic States |
9:00 am - 9:10 am | Discussion Leader: Marjori Matzke (Academia Sinica)
"Session introduction and data highlights"
|
9:10 am - 9:35 am | Steve Jacobsen (UCLA)
"Gene silencing in Arabidopsis"
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9:35 am - 9:45 am | Discussion |
9:45 am - 10:00 am | Maria Gutierrez-Arcelus (University of Geneva)
"Passive and active DNA methylation and the interplay with genetic variation in gene regulation"
|
10:00 am - 10:05 am | Discussion |
10:05 am | Coffee Break |
10:30 am - 10:45 am | Kim Nguyen (University of Minnesota)
"TALE architecture in chimeric proteins of TALE and DNMT3A-CCD methyltransferase (TALEM-D) mediated in vivo unique methylation patterns"
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10:45 am - 10:50 am | Discussion |
10:50 am - 11:15 am | Erica Larschan (Brown University)
"The CLAMP protein links MSL complex to the X-chromosome during Drosophila dosage compensation"
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11:15 am - 11:25 am | Discussion |
11:25 am - 11:40 am | Emilie Castonguay (University of Edinburgh)
"Identification of novel inhibitors of heterochromatin integrity through a chemical screen in fission yeast"
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11:40 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | Lars Jansen (Instituto Gulbenkian de Ciência)
"Stable retention of nucleosomes at active genes"
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12:10 pm - 12:20 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session A |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Erasure & Dynamics of Epigenetic States |
| Discussion Leader: Wolf Reik (Babraham Institute) |
7:30 pm - 7:55 pm | Wolf Reik (Babraham Institute)
"The role of DNA modifications in epigenetic reprogramming and signalling"
|
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Alexander Meissner (Harvard University)
"Epigenetic dynamics in stem cells and development"
|
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Miguel Ramalho-Santos (University of California - San Francisco)
"Tets can dance: Vitamin C is an epigenetic missing link in embryonic stem cells and beyond"
|
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Amnon Koren (Harvard University)
"Random replication of the inactive X chromosome"
|
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Nuclear Organization |
| Discussion Leader: Edith Heard (Institut Curie) |
9:00 am - 9:25 am | Edith Heard (Institut Curie)
"The nuclear and chromosome dynamics of X-chromosome inactivation"
|
9:25 am - 9:35 am | Discussion |
9:35 am - 9:50 am | Fred Berger (Temasek Life Sciences Laboratory)
"A new class of histone variant induces heterochromatin and promotes chromatin condensation"
|
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:55 am | Peter Fraser (Babraham Institute)
"Exploration of functional genetic and epigenetic landscapes in 3D chromosome structures"
|
10:55 am - 11:05 am | Discussion |
11:05 am - 11:20 am | Jack Bateman (Bowdoin College)
"Comparing enhancer action in cis and in trans"
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11:20 am - 11:25 am | Discussion |
11:25 am - 11:40 am | Maria-Elena Torres-Padilla (IGBMC)
"Heterochromatin establishment at mouse pericentromeres depends on nuclear position"
|
11:40 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | Jason Brickner (Northwestern University)
"Mechanism and conservation of nuclear pore-dependent transcriptional memory"
|
12:10 pm - 12:20 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session B |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | RNA-Based Epigenetic Mechanisms |
7:30 pm - 7:40 pm | Discussion Leader: Frédéric Chédin (University of California - Davis)
"Session introduction and data highlights" |
7:40 pm - 8:05 pm | Alyson Ashe (University of Cambridge)
"Multigenerational Epigenetic Memory in the Germline of C. elegans"
|
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Rob Martienssen (Cold Spring Harbor Laboratory)
"Germline reprogramming and epigenetic inheritance mediated by small RNA"
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8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:05 pm | Adele Murrell (University of Cambridge)
"Genomic imprinting and cotranscriptional splicing"
|
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Leah Matzat (National Institutes of Health)
"Messenger RNA is a functional component of a chromatin insulator complex"
|
9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Epigenomics |
| Discussion Leader: Joseph Ecker (Salk Institute) |
9:00 am - 9:25 am | Khai Luong (PacBio)
"Epigenomic profiling using SMRT technology"
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9:25 am - 9:35 am | Discussion |
9:35 am - 9:50 am | Soojin Yi (Georgia Institute of Technology)
"Evolution of human brains and DNA methylation"
|
9:50 am - 9:55 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:55 am | Joseph Ecker (Salk Institute)
"Methylation on the brain" |
10:55 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Dirk Schübeler (Friederich Miescher Institute)
"Instructing the epigenome in stem and differentiated cells"
|
11:30 am - 11:40 am | Discussion |
11:40 am - 12:10 pm | Henk Stunnenberg (NCMLS)
"The epigenome of groundstate mouse embryonic stem cells"
|
12:10 pm - 12:20 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session C |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Epigenetic Inheritance |
| Discussion Leader: Bill Kelly (Emory University) |
7:30 pm - 7:55 pm | Bill Kelly (Emory University)
"Memory of transcription past"
|
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Vincent Colot (Institut de Biologie de l'Ecole Normale Supérieure)
"Inheritance patterns of DNA methylation and transposable element mobilization in Arabidopsis"
|
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Craig Pikaard (Indiana University)
"Molecular memory, silent locus identity and epigenetic inheritance in Arabidopsis"
|
9:05 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Jiang Liu (Beijing Institute of Genomics, CAS)
"Sperm, but not oocyte, DNA methylome is inherited by Zebrafish early embryos"
|
9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Environmental Interactions |
9:00 am - 9:10 am | Discussion Leader: Jean Finnegan (CSIRO)
"Session introduction and data highlights" |
9:10 am - 9:35 am | Shunsuke Ishii (RIKEN)
"Inheritance of stress-induced chromatin alterations"
|
9:35 am - 9:45 am | Discussion |
9:45 am - 10:00 am | Stephen Santoro (Harvard University)
"The activity-dependent histone variant H2B.E modulates the life span of olfactory neurons"
|
10:00 am - 10:05 am | Discussion |
10:05 am | Coffee Break |
10:30 am - 10:55 am | Ortrun Mittelsten Scheid (Gregor Mendel Institute)
"Stress and epigenetic response"
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10:55 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Ueli Grossniklaus (University of Zurich)
"Is there epigenetic memory of heat stress?"
|
11:30 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Sally Mackenzie (University of Nebraska)
"Organelle-mediated elicitation of heritable epigenetic variation in plant development"
|
12:05 pm - 12:15 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session D |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Epigenetics and Disease |
| Discussion Leader: Anne Ferguson-Smith (University of Cambridge) |
7:30 pm - 7:55 pm | Sarah Clinton (University of Alabama - Birmingham)
"Epigenetics, Neurodevelopment and Risk for Anxiety and Depression in Model Rats"
|
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:20 pm | Jiemin Wong (East China Normal University)
"The UHRF Family Proteins Negatively Regulate De Novo DNA Methylation and Their Overexpression Causes DNA Hypomethylation in Cancer"
|
8:20 pm - 8:25 pm | Discussion |
8:25 pm - 8:50 pm | Richard Festenstein (Imperial College London)
"Antagonising heterochromatin formation in Friedreich's ataxia: a novel therapy for a prototypic position-effect disease?"
|
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Anne Ferguson-Smith (University of Cambridge)
"Meeting synthesis"
|
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |