Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session: RNA-Dependent Modes of Epigenetic Regulation |
| Discussion Leader: Craig Pikaard (Indiana University, USA) |
7:40 pm - 7:50 pm | Opening Remarks |
7:50 pm - 8:00 pm | Introduction by Discussion Leader |
8:00 pm - 8:45 pm | Anne Ferguson-Smith (University of Cambridge, United Kingdom) "From Imprinting to the Epigenome" |
8:45 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Jeanne Lawrence (University of Massachusetts Medical School, USA) "Regulating the
Epigenome via Chromosomal RNAs: Implications for Genome Biology and Chromosome
Pathology" |
9:20 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | New Epigenetic Phenomena |
| Discussion Leader: Eric Richards (Boyce Thompson Institute, USA) |
9:00 am - 9:20 am | Ueli Grossniklaus (University of Zurich, Switzerland) "Epigenetic
Variation and Plant Adaptation" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Ross Waller (University of Cambridge, United Kingdom) "Chromatin Without Histones: Dinoflagellates Present a New Model for Chromatin Structure and Organisation" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:15 am | Andrew Klocko (University of Oregon, USA) "Neurospora Importin α Is Required for Heterochromatin Formation and Proper Nuclear Organization" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:10 am | Chuan He (University of Chicago, USA) "Reversible RNA Methylation
in Gene Expression Regulation" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:35 am | Andrzej Wierzbicki (University of Michigan, USA) "Control of Chromatin Structure by Long Non-Coding RNA" |
11:35 am - 11:40 am | Discussion |
11:40 am - 11:55 am | Matthew Lorincz (University of British Columbia, Canada) "Impact of LTR Retrotransposons on the Transcriptome and Methylome in the Mouse Germline" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Barbara Panning (University of California, San Francisco, USA) "Investigation of the TET1-OGT Interaction in Embryonic Stem Cells" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Epigenetic Control of Development and Dosage |
| Discussion Leader: Robert Martienssen (Cold Spring Harbor Laboratory, USA) |
7:30 pm - 7:50 pm | Doris Wagner (University of Pennsylvania, USA) "A Hormone-Regulated Chromatin State Switch
During Organogenesis in Plants" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Alexander Gimelbrant (Dana-Farber Cancer Institute, USA) "Genes with Monoallelic Expression Play a Disproportionate Role in Individual Variation" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Susan Strome (University of California, Santa Cruz, USA) "Epigenetic Strategies for Germ Cells to Remember Their Germline Roots" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Christine Disteche (University of Washington, USA) "Bipartite Structure of the Inactive Mouse X Chromosome" |
9:20 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Epigenetic Control of Genome Integrity |
| Discussion Leader: Avraham Levy (Weizmann Institute of Science, Israel) |
9:00 am - 9:20 am | Kazufumi Mochizuki (Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Austria) "Small RNA-Mediated Trans-Recognition Network in
Tetrahymena DNA Elimination" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:45 am | Yuanyuan Kang (University of Colorado, USA) "Differential Deposition of CENP-A Defines Chromosomal Regions for Retention and Elimination in Nematode Programmed DNA Elimination" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:10 am | Jonathan Gent (University of Georgia, USA) "On How to Reach Equilibrium: Dynamics in Plant Centromeres" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:10 am | Gaelle Legube (University of Toulouse, France) "Chromatin Landscape at DNA Double Strand Breaks" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:35 am | Nickolai Tchurikov (Engelhardt Institute of Molecular Biology, Russia) "Hot Spots of DNA Double-Strand Breaks and Genomic Contacts of Human rDNA Units Are Involved in Epigenetic Regulation" |
11:35 am - 11:40 am | Discussion |
11:40 am - 11:55 am | Robert Feil (CNRS, France) "Condensins and HP1 Proteins Differentially Control Nucleosomal Chromatin Compaction in Living Cells" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Zachary Lewis (University of Georgia, USA) "Genome-Wide Redistribution of H3K27me3 Is Linked to Genotoxic Stress and Defective Growth" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Epigenetics and Nuclear Organization |
| Discussion Leader: Edith Heard (Institute Curie, France) |
7:30 pm - 7:50 pm | Pamela Geyer (University of Iowa, USA) "Investigations of Nuclear Architectural Proteins in Drosophila" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Karen Miga (University of California, Santa Cruz, USA) "The Dark Side of the
Genome: A High-Resolution Study of Human Centromeric Regions" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Victor Corces (Emory University, USA) "Stress-Induced Re-Arrangement of Chromosome 3D
Organization" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Ting Wu (Harvard Medical School, USA) "Single-Molecule Super-Resolution In Situ Imaging of Chromosomal DNA and Haplotype Visualization Using Oligopaints" |
9:20 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Dynamics of Epigenetic States |
| Discussion Leader: Steven Jacobsen (University of California, Los Angeles / Howard Hughes Medical Institute, USA) |
9:00 am - 9:20 am | Frederic Berger (Gregor Mendel Institute, Austria) "Histone Variants and Regulation of Transcription in Arabidopsis" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:45 am | Anne Dodson (University of California, Berkeley, USA) "Heritable Capture of Heterochromatin Dynamics in Saccharomyces cerevisiae" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:10 am | David Katz (Emory University, USA) "LSD1 Epigenetically Regulates Cell Fate During Differentiation and in the Prevention of Neural Disease" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:10 am | Bradley Cairns (University of Utah, USA) "Epigenetic and Transcription Transitions in the Germline and Early Embryos" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:35 am | Lacramioara Bintu (California Institute of Technology, USA) "Dynamics of Epigenetic Regulation at the Single-Cell Level" |
11:35 am - 11:40 am | Discussion |
11:40 am - 11:55 am | Alessandro Gardini (University of Miami, USA) "Integrator Mediates the Biogenesis of Enhancer RNAs" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Robert Schmitz (University of Georgia, USA) "Encyclopedia of
Eukaryotic DNA Methylation – From Patterns to Mechanisms and Functions" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Inheritance of Epigenetic States |
| Discussion Leader: Vincent Colot (Institut de Biologie de l'Ecole Normale Supérieure, France) |
7:30 pm - 7:50 pm | Scott Kennedy (Harvard Medical School, USA) "Multigenerational Epigenetic Inheritance" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:15 pm | John McCarrey (University of Texas at San Antonio, USA) "Tertiary Epimutations
– A Novel Paradigm Contributing to Transgenerational Epigenetic Inheritance" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:35 pm | Krzysztof Brzezinka (University of Potsdam, Germany) "Regulation of Heat Stress Memory and Chromatin Dynamics in Arabidopsis thaliana" |
8:35 pm - 8:40 pm | Discussion |
8:40 pm - 8:55 pm | Benjamin Carone (Williams College, USA) "Preferential Retention of Nucleosomes in Gene-Poor Genomic Loci in Murine Sperm" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Petra Hajkova (MRC Clinical Sciences Centre, United Kingdom) "Chromatin Dynamics in the Mouse Oocyte" |
9:20 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Targeted Epigenetic Modification |
| Discussion Leader: Marisa Bartolomei (University of Pennsylvannia, USA) |
9:00 am - 9:20 am | Peter Waterhouse (Centre for Tropical Crops and Biocommodities, Australia) "Self, Non-Self and Movement" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:45 am | Maxim Greenberg (Institut Curie, France) "Life-Long Epigenetic Setting of the Gpr1-Zdbf2 Locus Through RNA-Mediated DNA Methylation" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:10 am | Karmella Haynes (Arizona State University, USA) "Epigenetic
Engineering of Human Cells with Fusion Proteins" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:10 am | Bradley Bernstein (Harvard University, USA) "Epigenetic Plasticity of Cancer Stem Cells" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:35 am | Olivia Walker (University of Cambridge, United Kingdom) "The Interplay Between Rapid Epigenetic and Metabolic Changes on Expressing a Cancer-Associated Mutation" |
11:35 am - 11:40 am | Discussion |
11:40 am - 11:55 am | Andrew Johnston (Albert Einstein College of Medicine, USA) "A Case Study in Epigenomic Research Reproducibility: The Elusive Effect of KDM5b Depletion on Embryonic Stem Cell Transcription and Intragenic Promoter Induction" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Jose Eirin-Lopez (Florida International University, USA) "The Discovery of Histone MacroH2A in Invertebrates Sheds Light into the Functional Evolution of Histone Variants" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Epigenetics and Disease |
| Discussion Leader: Anne Ferguson-Smith (University of Cambridge, United Kingdom) |
7:30 pm - 7:50 pm | Samie Jaffrey (Weill Cornell Medical College, USA) "Mechanisms of Epigenetic Silencing Induced by Trinucleotide Repeat RNA" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Todd Macfarlan (National Institute of Child Health and Human Development, NIH, USA) "The Initiation of Heterochromatic Silencing in
Mammals by an Adaptive Viral Surveillance System" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Viviane Labrie (Centre for Addiction and Mental Health, Canada) "Epigenetics of Lactose Intolerance and Lactase Persistence" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Heather True (Washington University in St. Louis School of Medicine, USA) "One Prion, Two Prion,
Red Prion, Blue Prion ..." |
9:20 pm - 9:30 pm | Discussion |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |