Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Chromatin Dynamics in Development
Discussion Leaders: C. Jake Harris (University of California, Los Angeles, USA) and Jaclyn Noshay (University of Minnesota, USA)
3:45 pm - 4:15 pm
Bradley Cairns (University of Utah, USA)
"Ordered Roles for Histone Variants and Polycomb Complexes in Embryonic Developmental Gene Regulation"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Regulation of Dynamic DNA/RNA Methylation
Discussion Leaders: Giovanni Carosso (Johns Hopkins School of Medicine, USA) and Léa Faivre (Free University of Berlin, Germany)
7:30 pm - 7:50 pm
Chan Zhou (University of Massachusetts Medical School, USA)
"Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell Type-Specific Methylation Patterns that Are Distinct from mRNAs"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Jessica Elmer (University of Cambridge, United Kingdom)
"Genetics and Evolution of Variably-Methylated Transposable Elements in Inbred Strains of Mice"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Isaac López-Moyado (La Jolla Institute for Immunology, USA)
"Paradoxical Association of TET Loss of Function with Genome-Wide Hypomethylation"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Christina Steadman (Los Alamos National Laboratory, USA)
"Mining the Genomic Landscape of Microalgae for Epigenetic Treasures"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Epigenetic Control of Transcription During Development
Discussion Leaders: Julie Ahringer (University of Cambridge, United Kingdom) and Danielle Little (University of Texas MD Anderson Cancer Center, USA)
9:00 am - 9:20 am
Brandon Carpenter (Emory University, USA)
"SPR-5; MET-2 Maternal Reprogramming Antagonizes H3K36me3 in the Control of Germline Versus Soma"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Dahong Chen (National Institutes of Health, USA)
"Chromatin Insulator-Mediated Epigenetic Regulation of Neuronal Maturation"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Myron Evans (St. Jude Children's Research Hospital, USA)
"Dual Regulation of PRC2 Activities Governs the Regionalization and Cell Differentiation of the Central Nervous System"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Saumya Gupta (Dana-Farber Cancer Institute, USA)
"Stable Epigenetic Variation in Intestinal Organoids"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Maintenance and Propagation of Chromatin States
Discussion Leaders: Yuan Wang (Boston Children's Hospital / Harvard Medical School, USA) and Chad Cockrum (University of California, Santa Cruz, USA)
1:30 pm - 1:50 pm
Júlia Torné (Institut Curie, France)
"Transcription-Coupled Dynamics of Old and New Histone H3: The Role of the Chaperone HIRA"
1:50 pm - 2:00 pm
Discussion
2:00 pm - 2:20 pm
Zachary Harvey (Stanford University, USA)
"A Prion Switch Controls Expression of Silent Information"
2:20 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes