Sunday, July 18th
7:30 P.M. - 10:00 P.M. | Transcriptional regulators in epithelia |
Elaine Fuchs, Discussion Leader
Elaine Fuchs, Transcriptional control in the epidermis and its appendages
Paul Khavari, NF-kB function in epithelial growth, death and response to injury
Marc van de Wetering, TCFs and epithelial differentiation
Bruce Spiegelman, PPARy and the treatment of epithelial neoplasms
Monday, July 19th
9.00 A.M. - 12:00 P.M. | Lessons from Drosophila |
Eli Knust, Discussion Leader
Eli Knust, Control of cell polarity in Drosophila
Talila Volk, Inductive interactions between muscles and their epidermal attachment cells in the Drosophila embryo
Katherine Shim, Migration of the tracheal epithelium in Drosophila
Ulrich Tepass, Cadherin function in Drosophila development
Rafi Kopan, Notch signaling and hair morphogenesis
| 4.30 P.M. - 6:00 P.M. | Posters |
| 7.00 P.M. - 9.30 P.M. | Issues Rising 1: experimental models of skin disease |
John Sundberg, Discussion Leader
John Sundberg, Skin diseases in inbred and mutant laboratory mice
Bruce Herron, Characterization of a phenocopy of waved mice
Masayuki Amagai, Development of a novel active disease mouse model for pemphigus vulgaris.
Susan Gilmour, Effect of ODC overexpression and an activated ras on epidermal growth and differentiation
Yinling Hu, Abnormal morphogenesis in epidermal differentiation and skeletal patterning in mice lacking IKKa.
Julie Segre, GKLF: A transcription factor required for establishing the skin's barrier function.
Thaddeus Stappenbeck, inappropriate differentiation of epithelial cell lineages induced in the proliferative compartment of the fetal mouse intestine by forced expression of a dominant active Racl.
Tuesday, July 20th
9:00 A.M. - 12:00 P.M. | Internal epithelia |
Henry Sun, Discussion Leader
Henry Sun, Structure and dynamic rearrangement of uroplakin plaques of mammalian urothelium
Jean-Pierre Kraehenbuhl, Epithelial plasticity: role of microorganisms and immune cells
Missy Wong, Mouse models for defining the role of ß-catenin signalling in intestinal epithelium
Jean-Noel Freund, Intestinal epithelial differentiation in response to laminin
| 4.30 P.M. - 6:00 P.M. | Posters |
| 7.00 P.M. - 9.30 P.M. | Issues Rising II: gene transfer, stem cells and gene therapy |
Lorne Taichman, Discussion Leader
Lorne Taichman, Introductory remarks.
Soosan Ghazizadeh, In vivo transduction of epidermal stem cells.
Kyonggeun Yoon, Sequence-specific gene correction by an RNA-DNA oligonucleotide in mammalian cells.
Jeff Morgan, Growth factor delivery from genetically modified skin grafts.
Bob Lavker, Fate studies of folliclar growth
Sally Lowell, Notch signalling in human epidermis.
Pritinder Kaur, Enrichment for murine epidermal label-retaining cells based on cell surface markers using a fluorescence-activated cell sorting (FACS) approach.
Jim Rheinwald, Properties of immortal cell lines arising from human epidermal keratinocyt and mesothelial cells stably transfected to express hTERT.
Wednesday, July 21st
9:00 A.M. - 12:00 P.M. | The cornified envelope |
Dennis Roop, Discussion Leader
Dennis Roop, The role of loricrin in the epidermis
Philippe Diian, Mouse involucrin and the formation of the cornified envelope
Kiyofumi Yamanishi, Transglutaminase 1 knockout mice
Peter Steinert, How cornified cell envelopes contribute barrier function
| 4.30 P.M. - 6:00 P.M. | Posters |
Wednesday, July 21st, evening
7:00 P.M. - 9:30 P.M. | Hair, nails and teeth |
Angela Christiano, Discussion Leader
Angela Christiano, Hair disorders in humans and mice
Cheng-Ming Chuong, Feather and scale patterning Cindy LoorniS, The role of Enl in skin and epidermal appendage development
Irma Thesleff, Regulation of epithelial morphogenesis in developing teeth
Thursday, July 22nd
9:00 A.M. - 12:00 P.M. | Control of epithelial growth and differentiation |
Werner Franke, Discussion Leader
Werner Franke, The plakophilin family in proliferating and differentiating cells
Filipo Giancotti, Integrin signalling and cell cycle control.
Walter Birchmeier, ß-catenin/armadillo in cell adhesion and signal transcluction
Paolo Dotto, The molecular switch between keratinocyte growth and differentiation
| 4.30 P.M. - 6:00 P.M. | Posters |
| 7.00 P.M. -9.30 P.M. | Issues Rising III: pre-millenial tension |
Irwin Freedberg, Discussion Leader
Irwin Freedberg, Where have we been? Where are we now? Where are we going?
Howard Baden, The cornified enveolpe: new perspectives.
Pierre A Coulombe, Pure suspensions of epidermal keratin intermediate filaments behave like weakly cross-linked gels.
Marjana Tomic-Canic, The role of the DNA in transcriptional regulation by nuclear receptors.
Mitchell F Denning, Protein kinase C trainslocates to mitochondria and potentiates caspase activation during ultraviolet radiation-induced apoptosis of human keratinocytes.
Bogi Andersen, A novel LIM only factor, LMO-4, coordinates the formation of transcriptional complexes in keratinocytes.
Carolyn Byrne, Role of epithelial initiation sites in epidermal development.
Tony Oro, Spatial and temporal regulation of hedgehog signaling: implications for hair follicle and BCC formation.
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