| Sunday, July 8 |
| 2:00pm-11:00pm | Arrival and registration |
| 4:30pm-6:00pm | Reception |
| 6:00pm | Dinner |
| 7:30pm-9:30pm | Epithelial Stem Cells |
| Session Chair: Fiona Watt |
| Fiona Watt, Imperial Cancer Research Fund
"Epidermal Stem Cells" |
| Robert Lavker, University of Pennsylvania Medical School
"Hair Follicle Stem Cells" |
| Irma Thesleff, University of Helsinki, Finland
"Epithelial Stem Cells in Teeth" |
| Jeff Gordon, Washington University School of Medicine
"Intestinal Epithelial Stem Cells" |
| Monday, July 9 |
| 7:30am-8:30am | Breakfast |
| 8:30am | Conference photograph |
| 9:00am-12:30pm | Epithelial Polarity |
| Session Chair: Eric Wieschaus |
| Buzz Baum, Harvard Medical School
"Organization of Apical-Basal Cell Polarity in Drosophila Epithelial Cells" |
| Shoichiro Tsukita, Kyoto University, Japan
"Structure and Functions of Tight Junctions" |
| Enrique Rodriguez-Boulan, Cornell University Medical College
"Sorting of Apical and Basolateral Proteins at the Golgi Complex" |
| Eric Wieschaus, Princeton University
"Junction Formation and Epithelial Polarity in the Drosophila Blastoderm" |
| 12:30pm | Lunch |
| 4:00pm-6:00pm | POSTER SESSION |
| 6:00pm | Dinner |
| 7:30pm-9:30pm | Signal Transduction Pathways in Epithelia |
| Session Chair: Joan Massague |
| Mark Krasnow, Stanford University
"FGFs and Tracheal Morphogenesis" |
| Erwin Wagner, Research Institute for Molecular Pathology, Vienna
"EGF Signalling and Epidermal Development" |
| Short Talk: Nicole Maas-Szabowski, DKFZ, Heidelberg, Germany
"Cytokine-Regulated Dermal-Epidermal Interaction is Antagonistically Controlled by c-Jun and JunB" |
| Joan Massague, Memorial Sloan Kettering Cancer Center
"TGFß, Signalling and Transcription in Keratinocytes" |
| Tuesday, July 10 |
| 7:30am-8:30am | Breakfast |
| 9:00am-12:30pm | Adhesion, Wnts, Shh and Epithelial Development |
| Session Chair: Elaine Fuchs |
| Jean-Paul Vincent, Medical Research Council, Cambridge, U.K.
"Boundaries in the Embryonic Epithelium of Drosophila" |
| Walter Birchmeier, University of Berlin, Germany
"b-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin" |
| Anthony Oro, Stanford University
"Shh Signaling in Hair Follicle and BCC Formation" |
| Short Talk: Yinling Hu, University of California, San Diego
"IKKa Controls Formation of the Epidermis Independently of NF-kB via a Differentiation Inducing Factor" |
| Elaine Fuchs, The University of Chicago
"Intercellular Adhesion and Wnts in Mammalian Skin Development" |
| 12:30pm | Lunch |
| 4:00pm-6:00pm | POSTER SESSION |
| 6:00pm | Dinner |
| 7:30pm-9:30pm | Pathogens, Epithelia and Cancer |
| Session Chair: Peter Howley |
| Robert Weinberg, MIT, Whitehead Institute Biomedical Research
"Mechanism of Formation of Human Epithelial Tumors" |
| Jorge Galan, Yale School of Medicine
"Salmonella Infections and Intestinal Epithelia" |
| Mina Bissell, Lawrence Berkeley National Laboratory
"The Structural Basis of Tissue Specificity in Mammary Epithelial Cells" |
| Peter Howley, Harvard Medical School
"Mechanisms of Papillomavirus Associated Carcinogenesis" |
| Wednesday, July 11 |
| 7:30am-8:30am | Breakfast |
| 9am-12:30pm | Epithelial Adhesion, Proliferation and Differentiation |
| Session Chair: Filippo Giancotti |
| Nick Brown, Wellcome/CRC Institute, U.K.
"Integrins and Signalling in Flies" |
| Arnoud Sonnenberg, The Netherlands Cancer Institute
"The Role of Integrins in Epithelial Polarity" |
| Arthur Mercurio, Beth Israel Deaconess Medical Center
"Integrins and Epithelial Cancers" |
| Zena Werb, University of California, San Francisco
"How Extracellular Proteolysis Regulates Branching Morphogenesis" |
| Filippo Giancotti, Memorial Sloan Kettering Cancer Center
"Integrin Signaling in Epithelial Cells" |
| 12:30pm | Lunch |
| 4:00pm-6:00pm | POSTER SESSION |
| 6:00pm | Dinner |
| 7:30pm-9:30pm | Issues Rising 1: Skin Disorders in Mice and Men |
| Session Chair: Angela Christiano |
| Avri Ben Ze'ev (short talk), Weizmann Institute of Science, Israel
"A Reciprocal Relationship Between the b-Catenin and p53 Pathways and its Implications for Colon Cancer Development" |
| Eliane Muller (short talk), Institute of Animal Pathology, University of Bern, Switzerland
"A Key Role for Plakoglobin in Maintaining Epidermal Architecture: a Diseased-Based Perspective" |
| Jim Rheinwald (short talk), Brigham and Women's Hospital and Harvard Medical School
"p16INK4A and p14ARF/p53 Expression as a Telomere-independent Senescence
Mechanism and Barrier to Immortalization in Keratinocytes" |
| Carolyn Byrne (short talk), University of Manchester, U.K.
"Late Developmental Fine-tuning of Barrier Function" |
| Thomas Magin (short talk), University of Bonn, Germany
"Beyond Structure: Epidermal Hyperproliferation and Induction of
c-myc and of 14-3-3 in Adult Keratin 10 Null Mice" |
| Angela Christiano, Columbia University
"The Hairless Phenotype: Insights into Hair Follicle Cycling" |
| Thursday, July 12 |
| 7:30am-8:30am | Breakfast |
| 9:00am-12:00pm | Epithelial Architecture |
| Session Chair: Kathleen Green |
| Pierre Coulombe, Johns Hopkins University School of Medicine
"Keratin Function in Developing and Remodeling Skin Epithelia" |
| Peter Koch, Baylor College of Medicine
"Epithelial Differentiation" |
| Peter Steinert, NIH
"Structural Features of the Cornified Cell Envelope" |
| Peter Elias, V.A. Medical Center
"The Epidermal Barrier" |
| Kathleen Green, Northwestern University Medical School
"Desmosome Assembly and Dynamics" |
| 12:30pm | Lunch |
| 4:00pm-6:00pm | POSTER SESSION |
| 6:00pm | Dinner |
| 7:30pm-9:30pm | Issues Rising II: Regulation of Growth, Differentiation, Life and
Death in Epithelia |
| Session Chair: Paul Khavari |
| David Prowse (short talk), ICRF, London
"Investigating Human Keratinocyte Cell Fate Regulation by b-Catenin and FOXN1 (Whn)" |
| Sarah Miller (short talk), University of Pennsylvania
"WNT Signals are Required for the Formation of Hair Follicles, Mammary Glands and Teeth" |
| Paolo Dotto (short talk), CBRC, Harvard Medical School and Massachusetts General Hospital
"Notch Signaling as a Direct Determinant of Keratinocyte Growth Arrest and Entry into Differentiation" |
| Julia Segre (short talk), NHGRI, National Institutes of Health
"KLF4's Role in Transcriptional Control of Epidermal Barrier Establishment" |
| Paul Khavari, Stanford University
"Epidermal Cell Cycle Control by Ras and its Effectors" |
