SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Cell Fate Decisions and Stem Cell Lineages in Epithelia |
| Session Chair: Elaine Fuchs and Co-Chair: Julia Reichelt |
7:30 pm - 8:00 pm | Elaine Fuchs (Rockefeller University)
"Stem cells, morphogenesis and polarity in skin" |
8:00 pm - 8:30 pm | Stefan Heller (Harvard Medical School)
"Inner ear stem cells - Implications for development and hair cell regeneration" |
8:30 pm - 9:00 pm | John West (University of Edinburgh)
"Stem cell maintenance of the corneal and conjunctival epithelia" |
9:00 pm - 9:30 pm | Christopher Potten (EpiStem, Ltd)
"Label Retaining Cells, Stem Cells and Genome Protection" |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Developmental Signaling Pathways in Epithelial Morphogenesis |
| Session Chair: Fiona Watt and Co-Chair: Emily Chu |
9:00 am - 9:35 am | Fiona Watt (Imperial Cancer Research Fund)
"Lineage Selection in Adult Epidermis" |
9:35 am - 10:15 am | Michael Karin (University of California, San Diego)
"IKKα: a Master Regulator of Epidermal Differentiation" |
10:15 am | Coffee Break / Photo |
10:45 am - 11:20 am | Dennis Roop (Baylor College of Medicine)
"Genetic Pathways Required for Epidermal Morphogenesis" |
11:20 am - 11:55 am | Sarah Millar (University of Pennsylvania)
"Intercellular signaling in skin appendage development and growth" |
11:55 am - 12:30 pm | Mark Peifer (University of North Carolina)
"The Regulation of Cadherin-Based Cell-Cell Adhesion During Morphogenesis" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session I: Morphogenesis & Development and Stem Cells & Specialized Cell Types |
5:30 pm - 7:30 pm | Structural Biology of Cell-Cell Junctions |
| Session Chair: Lawrence Shapiro and Co-Chair: Florence Scholl |
5:30 pm - 6:10 pm | Lawrence Shapiro (Columbia University)
"Structural Studies of Cadherin Ectodomain Interactions" |
6:10 pm - 6:50 pm | William Weis (Stanford University)
"Biochemical and Structural Analysis of Adherens Junction Assembly" |
6:50 pm - 7:30 pm | David Stokes (New York University)
"3D Architecture of Desmosomes by Electron Tomography" |
8:00 pm | Dinner |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | What Lies Beneath: Plasticity, Reprogramming and the Microenvironment |
| Session Chair: Colin Jahoda and Co-Chair: Hisham Bazzi |
9:00 am - 9:35 am | Cheng Ming Chuong (University of California, Los Angeles)
"Developmental Evolution of Skin Appendages" |
9:35 am - 10:15 am | Danielle Dhouailly (University of Grenoble)
"Signaling Leading to Metaplasia into a Cutaneous Appendage Forming Skin" |
10:15 am | Coffee Break |
10:45 am - 11:20 am | Colin Jahoda (University of Durham)
"Inductive Properties and Plasticity of Hair Follicle Cells" |
11:20 am - 11:55 am | Jeff Biernaskie (University of Toronto)
"Skin-derived Precursors (SKPs):Multipotent Embryonic Precursors that Persist in a Dermal Niche" |
11:55 am - 12:30 pm | Maya Sieber-Blum (Medical College of Wisconsin)
"The adult hair follicle: cradle for pluripotent neural crest stem cells" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session I: Morphogenesis & Development and Stem Cells & Specialized Cell Types |
5:30 pm - 7:30 pm | ISSUES RISING: Session 1 - Morphogenesis & Development and Stem Cells & Specialized Cell Types |
| Chair: Ian Mackenzie and Co-Chair: Maranke Koster |
5:30 pm - 5:50 pm | Kursad Turksen (Ottowa Health Research Institute)
"Directed Differentiation of Pluripotent Cells to Epidermal Lineage in vitro" |
5:50 pm - 6:10 pm | Ellen Lumpkin (University of California, San Francisco)
"Molecular Profiling Reveals Synaptic Release Machinery in Epidermal Merkel Cells" |
6:10 pm - 6:30 pm | Pritinder Kaur (Peter MacCallum Cancer Centre)
"Microenvironmental Regulation of Epidermal Tissue Renewal" |
6:30 pm - 6:50 pm | Peter Marinkovich (Stanford University)
"Role of Laminin-10 in Hair Development" |
6:50 pm - 7:10 pm | Xing Dai (University of California, Irvine)
"mOvo1 transcriptional repressor regulates epidermal development by repressing c-Myc expression and proliferation" |
7:10 pm - 7:30 pm | Stephen Jane (Royal Melbourne Hospital)
"Grhl3 and Lmo4 Interact Biochemically and Functionally to Regulate Epidermal Morphogenesis in Mice" |
8:00 pm | Dinner |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Epithelial Differentiation and Disease |
| Session Chair: Paolo Dottoand Co-Chair: Lisa Godsel |
9:00 am - 9:35 am | Paolo Dotto (University of Lausanne / Massachusetts General Hospital)
"Notch Signaling in the Integrated Control of Keratinocyte Growth, Differentiation and Tumor Suppression" |
9:35 am - 10:15 am | Paul Khavari (Stanford University)
"Signaling Regulators of Epidermal Proliferation and Tumorigenesis" |
10:15 am | Coffee Break |
10:45 am - 11:20 am | Pierre Coulombe (Johns Hopkins University)
"Novel Insights into Keratin Functions in the Skin" |
11:20 am - 11:55 am | Kathleen Green (Northwestern University)
"Discriminating Roles: Beyond Desmosomal Adhesion" |
11:55 am - 12:30 am | Laura Attardi (Stanford University)
"Perp is a p63-regulated gene essential for epithelial integrity" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session II: Death, Differentiation, Signalling & Cancer and Cytoskeleton & Cell Adhesion |
5:30 pm - 7:30 pm | Emerging Hot Topics 2004-2005 |
| Session Chair: Dennis Roop and Co-Chair: Valentina Greco |
5:30 pm - 6:00 pm | Jing Yang (Whitehead Institute)
"A New 'Twist' on Tumor Metastasis" |
6:00 pm - 6:20 pm | Vu Nguyen (University of Pennsylvania)
"Morphogenesis of Scales in the Zebrafish: A Model for Hair and Tooth Development" |
6:20 pm - 7:00 pm | Irwin Freedberg Lectureship: John Stanley (University of Pennsylvania)
"Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display" |
7:00 pm - 7:30 pm | Business Meeting |
8:00 pm | Dinner |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Neuroepithelium, Neural Crest and Sensory Epithelia |
| Session Chair: Ralf Paus and Co-Chair: Gavin Richardson |
9:00 am - 9:35 am | Ralf Paus (University of Hamburg)
"The Brain-Skin Connection: Clues from the Hair Follicle" |
9:35 am - 10:15 am | Marianne Bronner-Fraser (California Institute of Technology)
"Molecular analysis of neural crest induction" |
10:15 am | Coffee Break |
10:45 am - 11:20 am | Anne Calof (University of California, Irvine)
"Common Molecular Signals Relating Progression through the Neuronal Lineage in Olfactory Epithelium and other Sensory Epithelia" |
11:20 am - 11:55 am | Linda Barlow (University of Colorado)
"Epithelial Patterning in Vertebrate Taste Bud Development" |
11:55 am - 12:30 pm | Rachel Brewster (University of Maryland)
"Cadherin-mediated Mechanisms of Neural Tube Development" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session II: Death, Differentiation, Signalling & Cancer and Cytoskeleton & Cell Adhesion |
5:30 pm - 7:30 pm | ISSUES RISING: Session 2 - Death, Differentiation, Signalling & Cancer and Cytoskeleton & Cell Adhesion |
| Chair: Jouni Uitto and Co-Chair: Karine Raymond |
5:30 pm - 5:50 pm | Ian Smyth (Institute for Child Health, London)
"The Frem Genes: Modulators of Embryonic Epidermal Adhesion in Mouse and Man" |
5:50 pm - 6:10 pm | Alain Hovnanian (University of Toulouse, France)
"Loss of Epidermal Protease Inhibition: Lessons from Spink5 Knock-out Mice" |
6:10 pm - 6:30 pm | Thierry Magnaldo (Institut Gustave Roussy, France)
"PATCHED Mutations Responsible for the Nevoid Basal Cell Carcinoma Syndrome Impact Cutaneous Homeostasis with the Contribution of Mesenchymal Cells" |
6:30 pm - 6:50 pm | Xiao-Jing Wang (Oregon Health & Science University)
"TGFß1-mediated Epithelial-Mesenchymal Transition and Metastasis can be Uncoupled During Skin Carcinogenesis" |
6:50 pm - 7:10 pm | Carlo Pincelli (University of Modena and Reggio Emilia)
"Blockade of beta1 integrin activates caspase-8 (extrinsic) apoptotic pathway in keratinocyte stem cells and in transit amplifying cells" |
7:10 pm - 7:30 pm | Karine Raymond (Netherland Cancer Institute)
"Role of alpha 6 beta 4 integrin in regulation of stem cell quiescence" |
| Closing Remarks: Perspectives and Prospects |
8:00 pm | Dinner |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |