Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Visualizing Interactions in Epithelial Homeostasis and Disease
7:40 pm - 8:20 pm
"Using Advanced Dynamic and Multiplex Static Imaging to Understand Tissue Organization and Function"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
"Therapeutic and Genetic Approaches to Alopecia Areata and Skin Blistering Diseases"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Homeostatic Growth and Regeneration of Epithelia: Novel Concepts in Cell Death and Renewal
9:00 am - 9:20 am
"Plasticity and Epithelial Regeneration"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Clonal Competition in Squamous Carcinogenesis"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
"Cellular Reprogramming by Defined Factors Drives Tissue Repair Following Injury of the Intestinal Epithelium"
10:50 am - 11:00 am
Discussion
11:00 am - 11:10 am
"Eye to Eye: Visualizing Stem Cell Activity and Regeneration of the Live Corneal Epithelium"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Diverse Roles of Polycomb Repressive Complexes in Epidermal Stem Cell Maintenance and Differentiation"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"The Mitophagy Receptor NIX Is Unregulated During Epidermal Differentiation and Drives Mitochondrial Fragmentation via Drp1"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Single Cell RNA-Seq Reveals a Novel Cell Type in Airway Epithelium"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Distinct Functions for Class I HDACs in Epithelial Progenitor Cell Self-Renewal and Differentiation"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Evolution and Morphogenesis of Skin and Its Appendages
6:00 pm - 6:20 pm
"The Development and Evolution of Colour Patterns in Fishes"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"Diversification of Epidermal Differentiation Proteins During the Evolution of the Skin in Mammals, Reptiles and Birds"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
"Evo-Devo of Skin Stem Cells and Their Regulation"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Hox Demarcates Regional Regeneration of Skin"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Chromatin Dynamics During Epithelial Commitment"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Cancerous Growth, Migration and Invasion of Epithelia
9:00 am - 9:20 am
"Plasticity of Collective Invasion in Epithelial and Mesenchymal Cancer Cells"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Skin Stem Cells and Their Niche Interactions in Homeostasis and Cancer"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
"Target Genes and Target Cells in Skin Cancer"
10:50 am - 11:00 am
Discussion
11:00 am - 11:10 am
"Live Imaging of Coordinated Epidermal Stem Cell Differentiation and Self-Renewal in Mice"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Molecular Basis of Merkel Cell Carcinoma"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Chromatin Architectural Protein CTCF Controls Epidermal Barrier Formation, Hair Follicle Cell Fate Maintenance and Suppresses Inflammatory Responses in the Epithelium of Developing and Adult Skin"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Cancer Cell of Origin, Multipotency and Tumor Heterogeneity in the Mammary Gland"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Genetic and Epigenetic Determinants of Cell Fate
6:00 pm - 6:20 pm
"Distinguishing Plasticity from Fate During Intestinal Self Renewal"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"New RNA and Protein Regulators of Ras Signaling"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
"Emerging Roles of Hair Follicles' Transit Amplifying Cells in skin Development and Regeneration"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Dermal Adipocyte Lipolysis Is Required for Multiple Aspects of Skin Regeneration"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Genetic and Epigenetic Regulation of Skin Epithelial Stem Cell Lineages in and out of Their Niches"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Advances in Cell- and Tissue-Architecture Control
9:00 am - 9:20 am
"Imaging Healthy and Malignant Hematopoiesis: Active Cells in a Dynamic Environment"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Cadherins Are Key Determinants of Epidermal Polarity and Tension"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"NuMA:LGN Hetero-Hexamers Cluster Active Dynein Motors at the Cortex to Promote Planar Cell Divisions"
9:55 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
"Biomechanics of Stem Cell Fate Regulation"
10:50 am - 11:00 am
Discussion
11:00 am - 11:10 am
"Rugged Terrain: The Search for Oral Epithelial Stem Cells"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Interplay Between Intermediate Filaments and Redox Balance in Disease"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Desmosomal Cadherin Association with Tctex-1 and Contraction-Arp2/3 Drives Perijunctional Actin Polymerization to Promote Epidermal Stratification"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Novel Functions for Desmosomes in the Epidermis"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Cellular Stress Responses in Homeostasis and Degeneration
6:00 pm - 6:20 pm
"Age-Selective Segregation of Organelles During Stem Cell Division"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"Regulation of the Hair Follicle Stem Cell Niche During Hair Growth, Pigmentation and Aging"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
"Translating Epitranscriptome in Skin Stem Cells"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Bimodal Evolution of Clone Size Variation in the Interfollicular Epidermis Persists upon UVB Irradiation: Implications for Carcinogenesis"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Epithelial Cell Death Pathways in Inflammatory Diseases"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Epithelia Micro-Environment in Homeostasis and Disease
9:00 am - 9:20 am
"Spatial Transcriptomics and Single-Cell Lineage Tracing"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Fibroblast Heterogeneity in Skin Homeostasis and Disease"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:40 am
"Memory of Inflammation in Epidermal Stem Cells"
10:40 am - 10:45 am
Discussion
10:45 am - 11:05 am
"Principles of Skin Tissue Regeneration by Live Imaging"
11:05 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation"
11:25 am - 11:30 am
Discussion
11:30 am - 11:50 am
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Hair Follicle Stem Cells in Androgenetic Alopecia"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Novel Translational Concepts in Epithelial Based Disease
6:00 pm - 6:20 pm
"Translating Human Skin Microbiome Research for Primary Immune Deficiency and Atopic Dermatitis Patients"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"Novel Approaches to Target p63-Associated Genodermatoses"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
"Epigenetic Enhancers and SCC"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Causative Gene Identification and Pathogenesis-Based Therapies in Genodermatoses"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Neutrophils Play a Key Role in Acute and Chronic Itch"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Epigenetic Control of CD36+ Metastasis Initiating Cells by Dietary Fatty Acids"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure