Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Understanding Biological Systems at Different Scale Magnitudes
7:40 pm - 8:20 pm
"How Cadherins Helped Create Complex Epithelia"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
"Embryonic Bricklaying: The Nuclear Movements that Establish the Blastoderm Epithelium in Insect Embryos"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Stem Cells and Homeostasis
9:00 am - 9:20 am
"Cell Competition in Drosophila and Mammalian Epithelia"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Skin Stem Cells: Coping with Stress"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
"Stem Cell Competition in Skin Homeostasis and Aging"
10:50 am - 11:00 am
Discussion
11:00 am - 11:10 am
"Transcription Termination Regulates Keratinocyte Proliferation and Differentiation"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"The Cellular Basis of Touch-Dome Development"
11:25 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Deciphering Skin at the Single-Cell Level"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Understanding Principles of Differentiation in the Regenerating Epidermis"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Skin Regeneration and Ageing: Deterioration of the Microenvironment"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Regulation of Cytoarchitecture
7:30 pm - 7:50 pm
"Microtubules, Motors and Morphogenesis"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Role of Mechano-Transduction in Maintaining Stem Cell Quiescence"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Integrating Mechanics and Signaling to Shape Epithelial Barriers"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"The Mystery Beyond Stem Cell Mechanobiology"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Keratins Impact Fundamental Processes Involving the Nucleus"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Normal and Cancer Stem Cells in Skin Tumor Evolution"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Evolutionary Selection of Mutant Progenitors in Squamous Epithelia"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Group Photo / Coffee Break
10:30 am - 10:40 am
"Epithelial Transition Zones: Stem Cell Niche and Cancer"
10:40 am - 10:45 am
Discussion
10:45 am - 11:05 am
"Mechanisms Regulating Tumor Heterogeneity and EMT Transition States"
11:05 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Tumour-Host Interaction During Metastasis"
11:25 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Skin Cancer Prevention: A Look Upside-Down"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Extracellular Matrix: The Molecules that Rock!"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Epigenetic and Nuclear Architecture
7:30 pm - 7:50 pm
"RNA Methylation Links Protein Synthesis to Cell Metabolism"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Polycomb Repressive Complex 1 (PRC1) Preserves Epidermal Tissue Integrity Independently of PRC2"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Mechanisms Underlying Skin Epigenetic Regulation and Heterogeneity"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Mapping Signaling Pathway Modulation of the Airway Epithelium by Single Cell Analysis"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"The Nuclear Option: New Mechanisms of Tumor Evolution and Drug Resistance"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Tissue Sensing and Cross-Talk
9:00 am - 9:20 am
"Neuroimmune Interactions in Chronic Itchy Skin"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Exciting Touch: Epithelial-Neural Signaling Mechanisms in Mammals"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:40 am
"Microbial Roles in Maintenance and Defense of the Skin Barrier"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
"Biomechanical Forces Modulate Epithelial Stem Cell Self-Renewal and De-Differentiation in the Cornea"
10:55 am - 11:00 am
Discussion
11:00 am - 11:20 am
"Homeostatic Mechanisms of Skin Barrier and Their Disruption in Skin Inflammation"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Investigating the Role of Ca2+ in Regulating Epidermal Stem Cell Behaviors via Live Imaging"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"A New Model for Orchestrated Hair Follicle Morphogenesis and Stem Cell Induction"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Fibroblasts and Adipocytes in Skin Repair"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Niches of Organs and Appendages
5:30 pm - 5:40 pm
"A Genetic Basis for the Evolution of Adaptive Skin Appendage Traits in Humans"
5:40 pm - 5:45 pm
Discussion
5:45 pm - 5:55 pm
"Oesophageal Cell Fate Transitions: Development Meets Homeostasis"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:20 pm
"Bio-Complexity Patterning Principles Revealed by Evo-Devo Studies of Integuments"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"Mapping Distinct Molecular and Cellular States of Hair Follicle Dermal Niche Progenitors During Morphogenesis"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
"How Cell Competition Shapes Epidermal Development"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Hair Follicle and Immune Cell Interactions"
7:20 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Development and Regeneration
9:00 am - 9:20 am
"Stem Cell-Driven Developmental Transitions in Parasitic Flatworms"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"SOX2 Epidermal Overexpression Promotes Cutaneous Wound Healing via Activation of EGFR/MEK/ERK Signaling Mediated by EGFR Ligands"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Live Imaging of the Limbal Niche Reveals Distinct Regulation of Cellular Fate to Support Corneal Regeneration"
9:55 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
"SHH Signaling in Hair Follicle Neogenesis"
10:50 am - 11:00 am
Discussion
11:00 am - 11:10 am
" Exploring a Role for Metabolism in Stem Cell Activation and Transformation"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Growing Old in Ten Days: The Metanephric Progenitor Niche"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Polarity Signaling Ensures Epidermal Homeostasis by Coupling Cellular Mechanics and Genomic Integrity"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Re-Thinking Heterogeneity of Human Epidermal Stem Cells"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Targeting Regenerative Plasticity in Metastasis"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Grace Under Pressure: Maintaining the Balance Between Proliferation and Delamination in a Stratified Epithelium"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Impact of Our (Fatty) Diet on Metastasis: Why What We Eat Matters"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Wild-Type and SAMP1/8 Mice Show Age Dependent Changes in Distinct Stem Cell Compartments of the Interfollicular Epidermis"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Multiomic Characterization of Epidermal Differentiation"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure