Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Keynote Session: The Business of Cellular Diversity and Crosstalk in Epithelial Tissues
Discussion Leaders: Ujjwal Banerjee (Wellcome Sanger Institute, Cambridge, UK, United Kingdom) and Rebecca Wagner (German Cancer Centre (DKFZ), Germany)
3:15 pm - 3:45 pm
Yasmine Belkaid (National Institute of Allergy and Infectious Diseases, NIH, United States)
"Cellular Diversity in Epithelial Tissues"
3:45 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Cellular Diversity and Crosstalk in Epithelial Tissues; Emerging Concepts in Skin Development, Homeostasis, and Aging
Discussion Leaders: Seona Lee (Cornell University, United States) and Marten Winge (Program in Epithelial Biology, Khavari lab, Stanford, United States)
5:30 pm - 5:45 pm
Matthew Tierney (Rockefeller University, United States)
"Retinoic Acid Resolves Lineage Plasticity to Orchestrate a Regenerative Equilibrium between Stem Cell Fates"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Shalini Dimri-Wagh (Technion-Israel Institute of Technology, Israel)
"Repair of Total Stem Cell Loss: A Lesson from the Transparent “Skin” of the Eye"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Krystle Joy Ng (A*STAR skin research labs Singapore, Singapore)
"From Force to Fate: LINCing Cell Junctions to Nuclear Morphology"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Gina Pacella (University of Pennslyvania, United States)
"The Role of Histone Demethylase Utx in Epidermal Homeostasis"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Agustin Sola Carvajal (Karolinska Institute, Sweden)
"Organelle Age Landscape in Skin"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Emily Scott-Solomon (Harvard University, United States)
"The Root of Hair Loss: Nerves, Immune Cells, and Stem Cells in Stress Induced Alopecia"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Interdisciplinary Approaches to Investigate Epithelial Biology and Translating Innovative Biology to Effective Therapy
Discussion Leaders: Rishika Agarwal (University of Basel, Switzerland) and Neta Felsenthal (Institut Curie, France)
9:00 am - 9:15 am
Clarisse Ganier (King's College London, United Kingdom)
"Fine Mapping of Cell States in Healthy Human Skin across Anatomical Sites and Basal Cell Carcinoma"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Douglas Porter (Stanford University, United States)
"A Regulatory Atlas of Skin Disease Variants and Transcription Factors that Modulate Them"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Duligengaowa Wuergezhen (RIKEN Center for Biosystems Dynamics Research, Japan)
"Visualization and Functional Characterization of Basement Membrane Dynamics in the Developing Mouse Hair Follicles"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Uttkarsh Ayyangar (Institute for Stem Cell Science and Regenerative Medicine, India)
"Epidermis Directed Metabolic Rewiring of Macrophages Promotes Sterile Inflammation in Murine Skin"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Heather Dingwall (University of Pennsylvania Perelman School of Medicine, United States)
"A Transient Dermal Niche and Dual Epidermal Programs Underlie Sweat Gland Development"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Argyro Kalogeropoulou (Wellcome Sanger Institute, United Kingdom)
"A Cell Competition CRISPR Screen to Identify Genes Regulating Fitness"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Clémentine Villeneuve (Max Planck Institute for Molecular Biomedicine, Germany)
"Mechanical Forces across Compartments Coordinate Cell Shape and Fate Transitions to Generate Tissue Architecture"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: How to Persevere in the Changing Research Climate
Discussion Leaders: Sarah Krantz (National Cancer Institute, United States) and David Grommisch (Karolinska Institutet, Sweden)
1:30 pm - 2:30 pm
Panel Discussion
Persevering in the Changing Research Climate
Scott Atwood (University of California, Irvine, United States)
Ya-chieh Hsu (Harvard University, United States)
Kim Jensen (University of Copenhagen, Denmark)
Carien Niessen (University of Cologne, Germany)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes