| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | BIOINFORMATIC, GENOMIC, AND PROTEOMIC
APPROACHES TO PROBLEMS IN FERTILIZATION AND DEVELOPMENT |
| Discussion Leader: Mary Ann Handel (Jackson Laboratory) |
| Anna Neill (Scripps Institution of Oceanography)
"The Sea Urchin Sperm Membrane Proteome" |
| Mary Ann Handel (Jackson Laboratory)
"Mutagenesis as an unbiased approach for identification of genes required for fertility" |
| Jo Ann Stanton (University of Otago, New Zealand)
"Mapping the oocyte transcriptome" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:45 am | Photo |
| 9:00 am - 12:30 pm | SPERM MOTILITY AND CHEMOTAXIS |
| Discussion Leader: George Witman (University of Massachusetts) |
| George Witman (University of Massachusetts)
"Flagellar assembly, proteomics, and male infertility" |
| Winfield S. Sale (Emory University)
"The 9+2 axoneme and the control of motility" |
| Chris D. Wood (UNAM, Mexico)
"Calcium and sperm motility" |
| Benjamin Kaupp (Institut fuer Biologische Informationsverarbeitung, Germany)
"Mechanisms and Molecules of Chemotaxis in Sea Urchin Sperm" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | GAMETE MATURATION |
| Discussion Leader: Laurinda Jaffe (University of Connecticut) |
| Lisa Mehlmann (University of Connecticut)
"Gs mediated meiotic prophase arrest in vertebrate oocytes" |
| Khaled Machaca (University of Arkansas)
"Calcium signaling during oocyte maturation" |
| Takeo Kishimoto (Tokyo Institute of Technology, Japan)
"Signaling pathway leading to meiotic maturation in starfish oocytes" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | FUNCTIONAL MEMBRANE DOMAINS IN GAMETES |
| Discussion Leader: George Gerton (University of Pennsylvania) |
| Alexander Travis (Cornell University)
"Lipid rafts in sperm" |
| Bart Gadella (Utrecht University, Netherlands)
"Bicarbonate driven changes in the sperm membrane" |
| Nonunj Tanphaichitr (University of Ottawa, Canada)
"The role of sperm lipids in sperm-zona binding" |
| Jens Coorssen (University of Calgary, Canada)
"Using urchin cortical vesicles to understand regulated membrane fusion" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MOLECULAR ASPECTS OF SPERM-EGG INTERACTION |
| Discussion Leader: Catherine Thaler (Stanford University) |
| Daniel Hardy (Texas Tech University Health Sciences Center)
"Specificity and degeneracy in sperm-zona pellucida adhesion" |
| Masaru Okabe (Osaka University, Japan)
"Observation of sperm-egg interaction through gene-manipulated animals" |
| Tim Kroft (Emory University)
"FER-14 and SPE-42, two transmembrane proteins required for sperm-egg interaction during C. elegans fertilization" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | SIGNAL TRANSDUCTION IN SPERM |
| Discussion Leader: Harvey Florman (University of Massachusetts) |
| Melissa Jungnickel (University of Massachusetts)
"ZP3-mediated signal transduction and the acrosome reaction" |
| Marc Spehr (University of Maryland)
"Odorant receptor signaling in sperm" |
| Dejien Ren (University of Pennsylvania)
"CatSper ion channels in sperm function" |
| Jochen Buck (Cornell University)
"'Soluble' adenylyl cyclase induced signaling events in sperm" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | KEYNOTE LECTURE |
| Jerome F. Strauss, III (University of Pennsylvania Medical School)
“Feminism and the Future of Reproductive Biology” |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | SIGNALING EVENTS DURING EGG ACTIVATION |
| Discussion Leader: Jay Baltz (University of Ottawa, Canada) |
| Guillaume Halet (University College London, UK)
"Phosphoinositide signaling in egg activation" |
| Rafael Fissore (University of Massachusetts, Amherst)
"Maintenance of long-lasting Ca2+ oscillations in fertilized eggs" |
| Janice Evans (Johns Hopkins University)
"New insights into the mammalian membrane block to polyspermy" |
| Gary Wessell (Brown University)
“Cell surface changes at fertilization in the sea urchin” |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | GENE ACTIVATION DURING EARLY DEVELOPMENT |
| Discussion Leader: Kathy Foltz (University of California, Santa Barbara) |
| Michelle Roux (University of California, Santa Barbara)
"Proteomic analysis of signaling at egg activation" |
| Fabio Piano (New York University)
"Identifying genes involved in embryogenesis using RNA interference" |
| Michael Stitzel (Johns Hopkins University)
"A clean start: coordinate degradation of maternal proteins during the oocyte-to-embryo transition" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
