Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Advances in Fertility Control
Discussion Leaders: Shweta Bhagwat (Indian Institute of Technology Bombay, India) and Bidur Paudel (University of Massachusetts Amherst, USA)
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:05 pm
Zoë Johnston (University of Dundee, United Kingdom)
"High-Throughput Phenotypic Screening Using Human Spermatozoa for the Identification of Novel Compounds with Non-Hormonal Contraceptive Activity"
4:05 pm - 4:10 pm
Discussion
4:10 pm - 4:25 pm
William Skinner (University of California, Berkeley, USA)
"Sperm Mitochondrial Uncouplers: A Potential Pathway for Unisex Contraception"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Oocyte Maintenance and Development
Discussion Leaders: Madhulika Pathak (Indian Institute of Science, India) and Omar Jose (National Institutes of Health, USA)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:50 pm
Farners Amargant i Riera (Northwestern University, USA)
"Age-Dependent Dysregulation of the Hyaluronan Network in the Mammalian Ovary Is Associated with Altered Ovarian Biomechanical Properties"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:10 pm
Goli Ardestani (University of Massachusetts Amherst, USA)
"Multiple Channels Underlie Divalent Cation Influx and Maintain Calcium Homeostasis in Germinal Vesicle Mouse Oocytes"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:30 pm
Jacinta Martin (University of Newcastle, Australia)
"Investigation into the Presence and Functional Significance of Proinsulin C Peptide in the Female Germline"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:50 pm
Zhengpin Wang (National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA)
"FIGLA Is a Multifunctional Regulator of Mouse Oocyte Differentiation During Folliculogenesis"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:10 pm
Di Wu (National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA)
"EXO10 Mediated RNA Degradation Sculpts Oocyte Transcriptome During Growth-to-Maturation Transition"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Formation and Function of Spermatozoa
Discussion Leaders: Muhammet Ugur (Mississippi State University, USA) and Jessica Walters (University of Newcastle, Australia)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:20 am
Miguel (Mao) Leung (University of Oxford, United Kingdom)
"Imaging the Structural Organisation of Mammalian Sperm in a Near-Native State with Cryo-Electron Tomography"
9:20 am - 9:25 am
Discussion
9:25 am - 9:40 am
Xue Mei (Rutgers University, USA)
"Immunoglobulin Superfamily Proteins in Fertilization: From Worms to Humans"
9:40 am - 9:45 am
Discussion
9:45 am - 10:00 am
Maximilian Lyon (Washington University in St. Louis, USA)
"Novel SLO3 Inhibitors as Blockers of Human Sperm Capacitation"
10:00 am - 10:05 am
Discussion
10:05 am - 10:20 am
Heejin Choi (National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA)
"Chromosome 18 Pachytene piRNA Required for Sperm Head Morphogenesis"
10:20 am - 10:25 am
Discussion
10:25 am - 10:40 am
Katherine Rivera Gomez (Brooklyn College and the Graduate Center, CUNY, USA)
"What Meiotic Mutants Tell Us About the Cell and Centrosome Cycles in C. elegans Spermatocytes"
10:40 am - 10:45 am
Discussion
10:45 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Keynote Session: Reproductive Science Through the Ages: Insights from the Bench and for Life
Discussion Leaders: Morgan Lion (Queen's University, Canada) and Kohei Umezu (Tohoku University, Japan)
1:30 pm - 2:15 pm
Francesca Duncan (Northwestern University, USA)
"Reproductive Science Through the Ages: Insights from the Bench and for Life"
2:15 pm - 2:25 pm
Discussion
2:25 pm - 2:30 pm
Closing Remarks
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes