Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Receptor Tyrosine Kinase Signalling Pathways in Development
Discussion Leaders: Kel Vin Woo (Washington University in St. Louis, USA) and Emilie Dambroise (Institut Imagine (UMR 1163), INSERM, France)
3:45 pm - 4:15 pm
Philippe Soriano (Icahn School of Medicine at Mount Sinai, USA)
"RTK Signalling Pathways in Development"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Functional Roles of the FGF Signalling Pathway
Discussion Leaders: Abbie Fearon (ETH Zurich, Switzerland) and Diana Rigueur (University of Southern California, USA)
7:30 pm - 7:45 pm
William Marsiglia (New York University, USA)
"Characterization of Disease Causing Mutations Associated with FGF Receptor Tyrosine Kinases Reveals a Connected Network of Residues Involved in Kinase Activation"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Stephanie Kainrath (Institute of Science and Technology Austria, Austria)
"Light-Regulated Ligand Traps for Spatio-Temporally Precise Inhibition of Cell Signalling"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Luigi Maddaluno (ETH Zurich, Switzerland)
"Fibroblast Growth Factor Signalling Controls Interferon Response Genes and Antiviral Defense Through a Novel Rac1/Actin/MRTF-A Pathway"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Marta Gronska (Albert Einstein College of Medicine, USA)
"Dendritogenesis and Neurogenesis in the Dentate Gyrus of FGFR Mutants and Its Downstream Effectors"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Qian Wang (Columbia University, USA)
"PLCĪ³ Acts as a Negative Regulator of FGF Signalling in Lacrimal Gland Development"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Emilie Dambroise (Institut Imagine (UMR 1163), INSERM, France)
"Cranial Vault Development in Fgfr3 Null Zebrafish"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
FGFRs in Pathology and Therapeutics
Discussion Leaders: Luigi Maddaluno (ETH Zurich, Switzerland) and Phuong Thao Bui (University of Liverpool, United Kingdom)
9:00 am - 9:15 am
Abbie Fearon (ETH Zurich, Switzerland)
"FGRF3 Is an Important Regulator of Liver Repair After CCl4-Induced Injury"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Diana Rigueur (University of Southern California, USA)
"Characterization of the Conditional FGFR2 M391R Knock-in Mouse: A Model for Bent Bone Dysplasia Syndrome"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Molly Ryan (Yale University, USA)
"Understanding the Impact of the V561M FGFR1 Gatekeeper Mutation on Drug Resistance and Tumorigenicity"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
Elisa Fiorito (Norwegian Radium Hospital, Oslo University Hospital, Norway)
"Identifying Determinants of Oncogenic FGFR4 Signalling Important for Rhabdomyosarcoma Progression"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Jui-Yen Huang (Indiana University Bloomington, USA)
"Dysregulated FGFR3 Activation in Post-Mitotic Neurons Leads to Aberrant Cortical Development and Behavioral Deficits"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Mentorship and Career Progression
Discussion Leaders: Luis Daniel Rios Barrera (European Molecular Biology Laboratory, Germany) and Benediktas Kaminskas (University of East Anglia, United Kingdom)
1:30 pm - 1:45 pm
David Ornitz (Washington University in St. Louis, USA)
"On Becoming a Scientist"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Yoshikazu Nakamura (RIBOMIC Inc., Japan)
"Aptamer Therapeutics, Four Decades After the Discovery of FGF2"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Suzanne Mansour (University of Utah, USA)
"Successful Publishing"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
