SUNDAY |
7:30 pm | Molecular Dissection of Nectins and Integrins |
| Discussion Leader: Kenneth Yamada |
| Kenneth Yamada
"Fibronectin and integrin molecular interactions and functions" |
| Jane Sottile
"Molecular approaches to understanding fibronectin matrix assembly" |
| Ruth Chiquet-Ehrismann
"The complexity in regulating the expression of tenascins" |
MONDAY |
9:00 am | Structures and Assemblies |
| Discussion Leader: Deane Mosher |
| Deane Mosher
"Coordinate control of cell shape and fibronectin assembly" |
| Robert Liddington
"Crystal structure of the Mac-1 I domain" |
| Daniel Leahy
"Crystal structures of fibronectin type III domains" |
| Harold Erickson
"Fibronectin is stretchable" |
| Donna Peters
"Ultrastructural and biochemical analysis of fibronectin fibril formation" |
| Denise Hocking
"Role of III-1 in fibronectin matrix assembly" |
7:15 pm | Interactions at the Cell Membrane |
| Discussion Leader: Anne Woods |
| Anne Woods
"Signaling through syndecan-matrix interactions" |
| Tom Parsons
"Focal adhesion kinase & intracellular signaling" |
| Elizabeth Lord
"Pollination as a case of cell adhesion and cell movements in plants" |
| Filippo Giancotti
"Intracellular functions of the α6β4 integrin" |
TUESDAY |
9:00 am | Integration of Environmental Cues |
| Discussion Leader: Caroline Damsky |
| Caroline Damsky
"Integrins: Morphogenesis and tissue remodeling" |
| Rudolph Juliano
"Downstream events in integrin signaling" |
| Martin Schwartz
"Stimulation of inositol lipid synthesis by integrins is mediated by the small GTP binding protein Rho" |
| E. Helene Sage
"SPARC: An extracellular mediator of cell morphology, adhesion, and proliferation" |
| Fedor Berditchevski
"Evidence for association of α3β1 integrin with members of the transmembrane 4 (tetraspan) family" |
2:00 pm | Workshop I: Integrins as Therapeutic Targets |
| Discussion Leaders: Sarah Bodary and Roy Lobb |
7:15 pm | Developmental Roles for Nectins and Integrins |
| Discussion Leader: Richard Hynes |
| Richard Hynes
"Mutations in genes for adhesive proteins" |
| Liselotte Fessler
"Interactions of ECM proteins and integrins during Drosophila development" |
| Doug DeSimone
"Fibronectins and integrins in amphibian morphogenesis" |
| Louis Reichardt
"Neuronal interactions with the extracellular matrix" |
WEDNESDAY |
9:00 am | Modulation of Integrin Function |
| Discussion Leader: Mark Ginsberg |
| Mark Ginsberg
"Dynamic regulation of integrins" |
| Rick Assoian
"Effects of cell adhesion on G1 cyclins and tumor suppressors" |
| Fiona Watt
"Integrin expression and function in keratinocytes" |
| Jim McCarthy
"Integrins and proteoglycans in tumor invasion through basement membranes" |
7:15 pm | Nectins and Integrins in Cell-Cell Interactions |
| Discussion Leader: Nancy Hogg |
| Nancy Hogg
"LFA-1 mediated adhesion" |
| Doug Dean
"α4β1 and VCAM during development" |
| Judy White
"Integrins and disintegrins in mammalian fertilization and development" |
| Eric Brown
"Integrin associated protein/CD47" |
THURSDAY |
9:00 am | Matrix Regulation of Cell Function |
| Discussion Leader: Erkki Ruoslahti |
| Erkki Ruoslahti
"Integrins in extracellular matrix assembly and mechanisms of growth-controlling effects by the matrix" |
| Zena Werb
"Signal transduction by integrins: Cooperative processing of information" |
| David Cheresh
"Role of αvβ3 in angiogenesis" |
| Donald Ingber
"Transmembrane signaling across integrins and through the cytoskeleton" |
2:00 pm | Workshop II: Tissue Distribution of Nectins and Integrins |
| Discussion Leaders: Dean Sheppard and Clayton Buck |
7:30 pm | Keynote Address |
| Mina Bissell
"From laminin to lamin: How does extracellular matrix regulate gene expression?" |