Sunday, January 26
7:30 pm - Adhesion and Invasion
- Howard Petty - "Dynamic properties of β2 integrin
interactions with urokinase receptors"
- Wen-Tien Chen - "Integrin-protease connections"
- Vito Quaranta - "Cell migration regulated by basement membrane
ECM" (Short talk)
- Discussion Leader: David Cheresh - "Role of integrins in
angiogenesis and cellular invasion"
Monday, January 27
9:00 am - Integrin Signaling
- Martin Schwartz - "Integrins, G-proteins, and PKC"
- Zena Werb - "Compartmentalization of signals from ECM"
- Patricia Keely - "Cdc42-induced signaling alters α2β1-mediated
epithelial cell responses" (Short talk)
- Filippo Giancotti - "Regulation of cell proliferation by
the α6β4 integrin" (Short talk)
- Kristiina Vuori - "Integrin dependent phosphorylation events"
- Discussion Leader: Kenneth Yamada - "Integrins, growth
factors, MAP kinase, and gene expression"
4:00 pm - Poster Session I
7:15 PM - Integrin-associated Proteins
- Eric Brown - "Structure function analysis of integrin-associated
protein (CD47)"
- Harold Chapman - "Effects of β1 integrin association
with UPAR (CD87)"
- Fedor Berditchevski - "Characterization of integrin-TM4SF
protein complexes"
- Discussion Leader: Mark Ginsberg - "Integrin cytoplasmic
tail structures and functions"
Tuesday, January 28
9:00 am - Structure/function Analysis of Nectins and Integrins
- Robert Liddington - "The I domain: a regulated protein
recognition module"
- Daniel Leahy - "Role of divalent cation in CD11a/CD18 integrin
I domain structure"
- Jia-Huai Wang - "Structural features of ICAM-2" (Short
talk)
- Yoshi Takada - "Mutation of integrin ligand binding sites"
(Short talk)
- Michael Sheetz - "Dynamics of integrin movement in the
plasma membrane"
- Discussion Leader: Jean Schwarzbauer - "How to make a fibronectin
matrix"
4:00 pm Poster Session II
7:15 pm - Genetic Approaches/Knockouts
- Christina Parker - "The role of αEβ7 in mucosal immunity"
- Tanya Mayadas-Norton - "Neutrophil functions regulated
by αMβ2"
- Yoji Shimizu - "Regulation of cell adhesion in the immune
system: pathways to an active integrin"
- Discussion Leader: Richard Hynes - "Functional consequences
of integrin knockouts"
Wednesday, January 29
9:00 am - Effects of Integrin Ligands/ECM Proteins on Cells
- William Frazier - "Thrombospondin modulates integrin function
via IAP/CD47"
- Jo Adams - "Novel morphological and molecular responses
of cells to thrombospondin-1"
- Eugene Marcantonio - "β1 cytoplasmic domain dominant negative
effects in transgenic mice" (Short talk)
- Sandy Shattil - "Proximate regulation of integrin signaling"
- Ruth Globus - "Fibronectin and osteoblast survival"
(Short talk)
- Discussion Leader: Erkki Ruoslahti - "Fibronectin and fibronectin-binding
integrins in cancer"
4:00 pm - (Special session) Integrin-associated proteins
- Discussion Leaders: Eric Brown and Sandy Shattil
- Robert Yauch - "Specific interactions among integrins,
TM4SF proteins and phosphatidylinositol 4-kinase"
- Marvin Tanzer - "Calreticulin-integrin bi-directional signaling
complex"
- Marc Coppolino - "Calreticulin is essential for integrin
function, but not for calcium buffering"
- Ulhas Naik - "Isolation of a calcium binding protein that
interacts with αllb cytoplasmic tail"
- David Chang - "ICAP-1, a novel β1 integrin cytoplasmic
domain associated protein"
- Kiyoshi Mori - "Functional consequences of integrin association
with CD46"
7:30 pm - Keynote Address
- Lewis Cantley - "Signaling involving phosphatidylinositides"
Thursday, January 30
9:00 pm - Disintegrin/ADAMS Structures and Functions
- Duojia Pan - "Genetic analyses of ADAM functions during
neuronal cell fate determination"
- Atsuko Fujisawa-Sehara - "Expression and function of meltrins"
- Stefan Niewiarowski - "Functional consequences of eristostatin
inhibition of the α4β1 integrin" (short talk)
- Roy Black - "A metalloproteinase-disintegrin that releases
TNFα from cells"
- Discussion Leader: Judy White - "Regulation of an ADAM-integrin
interaction"
7:15 pm- Adhesion and Development
- Reinhard Faessler - "Integrin β1 function during development"
- Danny Brower - "Integrin regulation of Drosophila wing
morphogenesis"
- Michael Dipersio - "Role of α3β1 integrin in developing
skin" (Short talk)
- Dean Sheppard - "Roles of the epithelial integrin αVβ6
in pulmonary inflammation and fibrosis"
- Discussion Leader: Caroline Damsky - "β1 integrins and
morphogenesis"
Friday, January 31
- Conference officially closes after breakfast
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