| SATURDAY |
| 1:30 pm - 4:30 pm | Arrival and Check-in |
| 3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:15 pm - 4:00 pm | Keynote Presentation |
| 3:15 pm - 3:50 pm | Richard Hynes (Massachusetts Institute of Technology, US)
"Fibronectins, Integrins and Cell-ECM interactions" |
| 3:50 pm - 4:00 pm | Discussion |
| 4:00 pm - 5:30 pm | Poster Session I |
| 5:30 pm - 7:30 pm | Live imaging and modeling of integrin adhesion site dynamics |
| Discussion Leader: Nick Brown (University of Cambridge, UK) |
| 5:30 pm - 5:45 pm | Antti Arjonen (University of Turku, Finland)
"Endocytic trafficking of active and inactive beta1-integrins" |
| 5:45 pm - 5:50 pm | Discussion |
| 5:50 pm - 6:05 pm | Neha Gadhari (University of Bern, Switzerland)
"Study of responses to cyclic mechanical stress in fibroblasts confined to micro-patterned ECM substrates" |
| 6:05 pm - 6:10 pm | Discussion |
| 6:10 pm - 6:25 pm | Craig Lefort (La Jolla Institute for Allergy & Immunity, US)
"Differential requirement for talin-1 and kindlin-3 in LFA-1-dependent neutrophil rolling and arrest" |
| 6:25 pm - 6:30 pm | Discussion |
| 6:30 pm - 6:45 pm | Jacob Rullo (Toronto General Hospital, Canada)
"PI3K-dependent force sensing in tension bearing tethers is critical for stabilization of integrin-mediated leukocyte adhesion" |
| 6:45 pm - 6.50 pm | Discussion |
| 6:50 pm - 7:05 pm | Jutta Wellmann (University of Cambridge, UK)
"Mechanosensitivity of integrin-mediated muscle attachment" |
| 7:05 pm - 7:10 pm | Discussion |
| 7:10 pm - 7:25 pm | Lindsay Case (NIH, US)
"Ventral actin waves are coupled to a novel type of integrin-mediated adhesion complex" |
| 7:25 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | The integrin adhesome: new components and network interactions |
| Discussion Leader: Martin Humphries (University of Manchester, UK) |
| 9:00 am - 9:15 am | Gian Maria Sarra Ferraris (IFOM, Italy)
"Non-integrin cell adhesion triggers ligand-independent integrin signaling" |
| 9:15 am - 9:20 am | Discussion |
| 9:20 am - 9:35 am | Jeroen Pouwels (VTT Medical Biotechnology, Finland)
"Sharpin is an endogenous inhibitor of beta1-integrin activation" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 9:55 am | John Lock (Karolinska Institute, Sweden)
"Systems Microscopy of cell migration: integrating cellular behaviour and molecular configuration" |
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | Perrine Pinon (Medical Cener of Geneva, Switzerland)
"Functional distinction between mechanical and signalling motifs in the cytoplasmic tail of β3 integrins" |
| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 10:35 am | Aaron Meyer (Massachusetts Institute of Technology, US)
"Heterogeneity of growth factor motility responses among a panel of carcinoma and endometriosis cell lines" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Emily Joo (National Institutes of Health, US)
"The interplay of actomyosin contraction and post-translationally modified microtubules regulates adhesion maturation and cell migration" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Careers Advice for Young Scientists |
| 1:30 pm - 1:45 pm | Martin Humphries (University of Manchester, UK)
"How to apply for a successful postdoc position" |
| 1:45 pm - 2:00 pm | Richard Hynes (Massachusetts Institute of Technology, US)
"How to apply for a PI position" |
| 2:00 pm - 2:30 pm | Round Table Discussion |
| Discussion Leaders: Richard Hynes, Martin Humphries, Nick Brown and David Calderwood |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
