Saturday |
1:30 pm - 4:30 pm | Arrival and Check-in |
3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:15 pm - 4:00 pm | Keynote Session: The History and Future of
Cell Adhesion Research |
| Discussion Leader: Matthew Jones (University of Manchester, United Kingdom) |
3:15 pm - 3:50 pm | Jim Norman (Beatson Institute for Cancer Research, United Kingdom) "The History and Future of Cell Adhesion Research" |
3:50 pm - 4:00 pm | Discussion |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | Regulation of Cell Signaling by Matrix Dynamics and Mechanics |
| Discussion Leader: J. Matthew Barnes (University of California, San Francisco, USA) |
5:30 pm - 5:45 pm | Simon Arnoldini (ETH Zürich, Switzerland) "Probing the Mechanical Strain of Fibronectin Fibrils in Histological Tissue Sections Exploiting Peptides Inspired by Bacterial Adhesins" |
5:45 pm - 5:50 pm | Discussion |
5:50 pm - 6:05 pm | Alberto Elosegui-Artola (Institute for Bioengineering of Catalonia, Spain) "Matrix Mechanosensing and Nuclear Transduction by Talin and Integrin Bond Dynamics" |
6:05 pm - 6:10 pm | Discussion |
6:10 pm - 6:25 pm | Christine-Maria Horejs (Karolinska Institute, Sweden) "A Cryptic Extracellular Matrix Activity Mediates the Epithelial-to-Mesenchymal Transition in Embryonic Stem Cells and Epithelial Cells" |
6:25 pm - 6:30 pm | Discussion |
6:30 pm - 6:45 pm | Cassie Clarke (Cancer Research UK Beatson Institute, United Kingdom) "The Initiator Methionine Transfer RNA, tRNAiMet, Modulates ECM Secretion from Stromal Fibroblasts to Influence Tumour Growth and Cell Migration" |
6:45 pm - 6:50 pm | Discussion |
6:50 pm - 7:05 pm | Elizabeth Duperret (University of Pennsylvania, USA) "A Multiplex Integrin Screen Identifies Necessary Roles for Integrins avβ5 and avβ6 in Skin Tissue Generation and Squamous Cell Carcinoma Invasion" |
7:05 pm - 7:10 pm | Discussion |
7:10 pm - 7:25 pm | Despoina Katsougkri (Max Planck Institute of Biochemistry, Germany) "Kindlin-1 Regulates Integrin-Dependent and -Independent Oncogenic Signaling Pathways" |
7:25 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Coordination of Morphogenesis and Disease by Cell Adhesion |
| Discussion Leader: Valerie Weaver (University of California, San Francisco, USA) |
9:00 am - 9:15 am | Emily Lostchuck (University of British Columbia, Canada) "Cell-ECM Adhesion Facilitates Cell Mobility to Allow Force Transmission During Morphogenesis" |
9:15 am - 9:20 am | Discussion |
9:20 am - 9:35 am | Emilia Peuhu (University of Turku, Finland) "Regulation of Cell-ECM Interaction by Sharpin in the Developing Mouse Mammary Gland" |
9:35 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Hannah Green (University of Cambridge, United Kingdom) "Integrin Adhesion Proteins in Muscle Maintenance and Repair" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:15 am | Madeleine Oudin (Massachusetts Institute of Technology, USA) "Mena at the Nexus of Chemotaxis and Haptotaxis During Tumor Progression" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:35 am | Yekaterina Miroshnikova (University of California, San Francisco, USA) "Tissue Mechanics and Glioma Aggression" |
10:35 am - 10:40 am | Discussion |
10:40 am - 10:55 am | Michaela Rothova (Danish Stem Cell Center, Denmark) "Extracellular Matrix Patterning and Specification of the Prospective Foregut" |
10:55 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Engineering Approaches to Study the Regulation of Cell Fate by Adhesion |
| Discussion Leader: Charles Streuli (University of Manchester, United Kingdom) |
1:30 pm - 1:45 pm | Silvia R. M. Ferreira (King's College London, United Kingdom) "Spatial and Temporal Mapping of Mechanical Dose on Stem Cell Differentiation" |
1:45 pm - 1:50 pm | Discussion |
1:50 pm - 2:20 pm | Sara Wickstrom (Max Planck Institute for Biology of Aging, Germany) "Biomechanical Regulation of Cell Fate" |
2:20 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |