Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: The History of Food Allergy and Type 2 Immunity
Discussion Leader: Patricia Fulkerson (National Institute of Allergy and Infectious Diseases, NIH, United States)
7:40 pm - 8:25 pm
Scott Sicherer (Icahn School of Medicine at Mount Sinai, New York, United States)
"The History of Food Allergy"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:20 pm
David Artis (Weill Cornell Medicine, United States)
"Regulation of Allergic Inflammation"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Food Allergy Genetics and Epidemiology
Discussion Leader: Courtney Malo (Science Translational Medicine, United States)
9:00 am - 9:20 am
Rasika Mathias (Johns Hopkins University, United States)
"Food Allergy Genetics: A Perspective on Identifying Risk and Tailoring Therapy."
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
Ruchi Gupta (Ann & Robert H. Lurie Children's Hospital of Chicago / Northwestern University School of Medicine, United States)
"The Public Health Impact of Food Allergy: Prevalence, Severity, Disparities, and Access"
9:45 am - 9:50 am
Discussion
9:50 am - 10:10 am
Paul Turner (Imperial College London, United Kingdom)
"Fatal Anaphylaxis: Bad Luck or Something We Can Predict?"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
Carla Davis (Texas Children's Hospital / Baylor College of Medicine, United States)
"Biological Mechanisms Impacting Health Disparities in Allergic Disease"
11:05 am - 11:10 am
Discussion
11:10 am - 11:30 am
Cindy Ma (Garvan Institute of Medical Research, Australia)
"Atopic Disease in Inborn Errors of Immunity"
11:30 am - 11:35 am
Discussion
11:35 am - 11:55 am
Jonathan Lyons (University of California San Diego, United States)
"Genetic Disorders and Traits in Severe Allergic Inflammatory Responses"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Pamela Guerrerio (NIAID, NIH, United States) and DeBroski Herbert (University of Pennsylvania, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Mechanisms of Type 2 Immunity
Discussion Leader: Lisa Wheatley (National Institute of Allergy and Infectious Diseases, NIH, United States)
7:30 pm - 7:50 pm
Mark Kaplan (Indiana University, United States)
"Allergen-Specific Inhibitors of Systemic Anaphylaxis"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:05 pm
Short Talk Selected from Poster Abstracts
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
DeBroski Herbert (University of Pennsylvania, United States)
"Initiation of Allergic Inflammation by Sensory Neurons"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
Marsha Wills-Karp (Johns Hopkins Bloomberg School of Public Health, United States)
"Innate Immune Mechanisms Regulating Type-2 Immunity"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Early Introduction and Tolerance
Discussion Leader: Alkis Togias (National Institute of Allergy and Infectious Diseases, NIH, United States)
9:00 am - 9:20 am
Asma Nusrat (University of Michigan, United States)
"Plasticity of the Intestinal Mucosal Barrier: Insights into Epithelial Junctional Signaling and Barrier Control"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
Katie Cockburn (McGill, Canada)
"Keeping Up with the Neighbors: Understanding Local Control of Epidermal Stem Cell Behaviors with Intravital Imaging"
9:45 am - 9:50 am
Discussion
9:50 am - 10:10 am
Brian Vickery (Emory University, United States)
"Can Tolerance be Restored Through Early Treatment of Allergic Infants and Toddlers?"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
Corinne Keet (University of North Carolina, Chapel Hill, United States)
"Are There Long-Term Consequences of Asymptomatic Food Sensitization?"
11:05 am - 11:10 am
Discussion
11:10 am - 11:30 am
Pamela Guerrerio (NIAID, NIH, United States)
"Loss-of-Function Variants in Transforming Growth Factor Beta (TGFb) and Allergic Disease"
11:30 am - 11:35 am
Discussion
11:35 am - 11:55 am
Helen Brough (Guy’s and St. Thomas’ Hospital and King's College London, United Kingdom)
"Targeting the Skin for Allergy Prevention"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Mechanisms of Sensitization, Skin and Gut
Discussion Leader: Adora Lin (National Institute of Allergy and Infectious Diseases, United States)
7:30 pm - 7:50 pm
Rodney Newberry (Washington University in Saint Louis School of Medicine, United States)
"Gut Epithelial Cells as Participants in Allergy"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:05 pm
Short Talk Selected from Poster Abstracts
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Joan Cook-Mills (Indiana University School of Medicine, United States)
"Mechanisms for Initiation of Food Allergy by Skin Pre-Disposed to Atopic Dermatitis"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
Scott Boyd (Stanford University School of Medicine, United States)
"B Cell Repertoires and Phenotypes in Food Allergy and Oral Immunotherapy"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Environmental Drivers of Sensitization and Reactivity
Discussion Leader: Christine Olsen (Food Allergy Science Initiative , United States)
9:00 am - 9:20 am
Mubeccel Akdis (Swiss Institute of Allergy and Asthma Research, Switzerland)
"Role of Allergen-Specific B Cell in Cow’s Milk-OIT-Induced Desensitization, Remission, and Natural Outgrowth"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
Cathryn Nagler (The University of Chicago, United States)
"Bacterial Metabolites Regulate Allergic Responses to Food"
9:45 am - 9:50 am
Discussion
9:50 am - 10:10 am
Andrew Macpherson (University of Bern, Switzerland)
"Diet and Microbiota Drivers for the B Cell Repertoire"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
Supinda Bunyavanich (Icahn School of Medicine at Mount Sinai, United States)
"Food Allergy From a Transcriptomic Lens"
11:05 am - 11:10 am
Discussion
11:10 am - 11:30 am
Chrysothemis Brown (Memorial Sloan Kettering Cancer Center, United States)
"Early Life Imprinting of Intestinal Tolerance"
11:30 am - 11:35 am
Discussion
11:35 am - 11:55 am
Michael Fischbach (Stanford University, United States)
"Understanding and Manipulating Immune Modulation by the Microbiome"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
T Cells in IgE and Non-IgE-Mediated Food Allergies
Discussion Leader: Zuhair Ballas (University of Iowa, United States)
7:30 pm - 7:50 pm
Onyinye Iweala (University of North Carolina at Chapel Hill, United States)
"T Cell Responses in Alpha-Gal Syndrome"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:05 pm
Short Talk Selected from Poster Abstracts
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Eric Wambre (Mount Sinai Hospital, United States)
"Immunologic Phenotypes of Food Allergic Diseases"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
Cecilia Berin (Northwestern University, United States)
"Pathophysiology of FPIES"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Immunotherapy Outcomes and Mechanisms
Discussion Leader: Daniel Rotrosen (NIAID, United States)
9:00 am - 9:20 am
Robert Wood (Johns Hopkins University School of Medicine, United States)
"Successes and Failures of Oral Immunotherapy"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
Edwin Kim (University of North Carolina School of Medicine, United States)
"Immune Modulation and the Potential for Remission after Peanut Sublingual Immunotherapy"
9:45 am - 9:50 am
Discussion
9:50 am - 10:10 am
Graham Roberts (University of Southampton, United Kingdom)
"Preventing Food Allergy: Moving from Efficacy to Effectiveness"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
R. Sharon Chinthrajah (Stanford University School of Medicine, United States)
"Biologics in Food Allergy: A Jump Start"
11:05 am - 11:10 am
Discussion
11:10 am - 11:30 am
Scott Smith (VANDERBILT UNIVERSITY MEDICAL CENTER, United States)
"Epitope Endgame: Atomic Structure of IgE Epitopes"
11:30 am - 11:35 am
Discussion
11:35 am - 11:55 am
Sara Prickett (Aravax Pty Ltd, Australia)
"Targeting T Cells to Treat Food Allergy"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Mast Cells, Basophils and Mechanisms of Reactivity
Discussion Leader: Laurie Dempsey (Nature Immunology, United States)
7:30 pm - 7:40 pm
Short Talk Selected from Poster Abstracts
7:40 pm - 7:45 pm
Discussion
7:45 pm - 8:05 pm
Jenny Hallgren Martinsson (Uppsala University, Sweden)
"Mast Cells and their Progenitors in Allergic Lung Inflammation"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Kensuke Miyake (Tokyo Medical and Dental University (TMDU), Japan)
"Pro-Resolving Roles for Basophils and Monocyte-Derived Macrophages in IgE-Mediated Skin Allergy."
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
Hans Oettgen (Boston Children's Hospital / Harvard Medical School, United States)
"IgG Antibodies Regulate the Pro-Inflammatory Program of IgE: Allergen-Activated Mast Cells"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
General Discussion
9:20 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure
