Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Eosinophilic Esophagitis
Discussion Leader: Daniel Lozano-Ojalvo (Icahn School of Medicine at Mount Sinai, USA)
3:45 pm - 4:00 pm
Julianna Dilollo (The Children's Hospital of Philadelphia Research Institute, USA)
"Food Allergen Specificity of Circulating T Cells in Eosinophilic Esophagitis Patients"
4:00 pm - 4:05 pm
Discussion
4:05 pm - 4:20 pm
Duncan Morgan (Massachusetts Institute of Technology, USA)
"Single-Cell RNA Sequencing Identifies Pathogenic Features of T Cells in Eosinophilic Esophagitis"
4:20 pm - 4:25 pm
Discussion
4:25 pm - 4:30 pm
General Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Pathogenesis of Food Allergy
Discussion Leader: Adora Lin (Children's National Hospital / George Washington University, USA)
7:30 pm - 7:45 pm
Justine Noel (Icahn School of Medicine at Mount Sinai, USA)
"Impact of Stress Hormone CRH on Neonatal Immune Function and Th2 Priming"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Catherine Pizzarello (School of Medicine and Dentistry, University of Rochester, USA)
"Human Milk Modulates LPS-Induced Intestinal Epithelial Cell IL-8 Expression and Dendritic Cell Activation"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Johanna Smeekens (University of North Carolina at Chapel Hill, USA)
"Environmental Adjuvants Present in Household Dust Affect Airway Sensitization to Peanut"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Gowthaman Uthaman (Yale University, USA)
"Discovery of a T Follicular Helper Cell Subset that Drives Anaphylactic IgE"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Erin Steinbach (University of North Carolina at Chapel Hill, USA)
"Interrogating Intestinal Barrier Function in Peanut Allergy"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Tong Zhang (Icahn School of Medicine at Mount Sinai, USA)
"The Role of the Terminal Ileum in Food Aversion"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Keynote Session: Prevention of Food Allergies / Diagnosis and Treatment of Food Allergy
Discussion Leader: Gowthaman Uthaman (Yale University, USA)
9:00 am - 9:30 am
Gideon Lack (King's College London, United Kingdom)
"Innovations in Preventing Food Allergy"
9:30 am - 9:40 am
Discussion
9:40 am - 9:55 am
Nicole Ramsey (Icahn School of Medicine at Mount Sinai, USA)
"High Dimensional Basophil Activation by Mass Cytometry: Utility of Lyophilized Activation Kits"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Adora Lin (Children's National Hospital / George Washington University, USA)
"Peanut-Allergic Children Display Altered B Cell Responses to IL-10 and Decreased Peripheral IL-10+ B Cells"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Kevin Hughes (University of Michigan, USA)
"Nanoparticle Delivery of Antigen Attenuates Anaphylactic Response in a Murine Model of Peanut Allergy"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Wenming Zhang (Sean N. Parker Center for Allergy and Asthma Research, Stanford University, USA)
"RNA-Seq of Gastrointestinal Biopsies During Oral Immunotherapy Reveals Changes in IgA Pathway"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel / Keynote Session: Food Allergy in Perspective
Discussion Leader: Wayne Shreffler (Massachusetts General Hospital / Harvard Medical School, USA)
1:30 pm - 2:30 pm
Panel Discussion
Career Paths in Food Allergy
Richard Insel (Janssen Pharmaceuticals, USA)
Cecilia Berin (Icahn School of Medicine at Mount Sinai, USA)
Stephanie Eisenbarth (Yale University School of Medicine, USA)
Hans Oettgen (Boston Children's Hospital / Harvard Medical School, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
