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Food Allergy (GRS)

Gordon Research Seminar

Food Allergy Pathogenesis, Immunotherapy and Tolerance in the COVID-19 Pandemic

November 12 - 13, 2022

Chairs Nicole Ramsey and Wenming Zhang

Residence Inn at Oxnard River Ridge

2101 West Vineyard Ave

Oxnard, California, United States

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Food Allergy is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting-edge ideas.The focus of this meeting is on discussing food allergy research with other trainees and early-career scientists, with mentorship from senior scientists in the field. There is a plethora of research being done to elucidate the mechanisms of how food allergy develops and potential ways to treat it, and the Gordon Research Seminar on Food Allergy aims to be a venue to showcase the variety of work being done. The meeting will feature poster sessions, talks focusing on the frontiers of food allergy research, and a career panel of senior researchers in the field.

Related Meeting

This GRS will be held in conjunction with the "Food Allergy" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Food Allergy and Immunotherapy Discussion Leader: Cynthia Kanagaratham (Boston Children's Hospital, United States)
3:45 pm - 3:50 pm	Introduction by Discussion Leader
3:50 pm - 4:00 pm	Caitlin Burk (Massachusetts General Hospital, United States) "Preliminary Data Suggest that Interferon Responses in CD4+ T Cells and TNF-alpha Signaling in the GPR15+ Subset May be Associated with Gastrointestinal Adverse Events During Peanut Oral Immunotherapy"
4:00 pm - 4:05 pm	Discussion
4:05 pm - 4:15 pm	Michael Saunders (University of Michigan, United States) "Allergen-Encapsulating Biodegradable Nanoparticles as an Allergen-Specific Immunotherapy"
4:15 pm - 4:20 pm	Discussion
4:20 pm - 4:30 pm	General Discussion
4:30 pm - 6:00 pm	Poster Session
4:30 pm - 4:35 pm	Discussion
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Mechanism and Pathogenesis of Food Allergy Discussion Leaders: Mariana Waldetario (Mount Sinai, United States) and Caitlin Burk (Massachusetts General Hospital, United States)
7:30 pm - 7:35 pm	Introduction by Discussion Leader
7:35 pm - 7:45 pm	Jamie Blum (Stanford University/HHMI, United States) "Identification of Antigens and Tolerizing Components from Commonly Consumed Foods"
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:00 pm	Charlotte Castenmiller (Amsterdam University Medical Centre, The Netherlands) "The Major Peanut Allergens are Taken Up By Dendritic Cells Via Different Routes and Receptors"
8:00 pm - 8:05 pm	Discussion
8:05 pm - 8:15 pm	Tamara Haque (NIAID, United States) "Dysregulated TGF-ß Signaling Leads to Cell-Intrinsic Changes in T cell Development that Promote Allergic Inflammation"
8:15 pm - 8:20 pm	Discussion
8:20 pm - 8:30 pm	Emily Grydziuszko (McMaster University, Canada) "CD4+ Memory T Cells Seeded Early During Sensitization hold Memory of IgE Responses in Food Allergy"
8:30 pm - 8:35 pm	Discussion
8:35 pm - 8:45 pm	Yasmeen El Ansari (Boston Children's Hospital, United States) "Ig A Exhibits Calcium- and Sialic Acid-dependent Binding to Mast Cells and Inhibits IgE-mediated Activation in an Antigen-specific Fashion"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:00 pm	Allyssa Phelps (McMaster University, Canada) "Reprogramming of Pathogenic IgE Memory with IL-4Ra Blockade"
9:00 pm - 9:05 pm	Discussion
9:05 pm - 9:15 pm	Daniel Waizman (Yale University, United States) "Skin Damage Signals Mediate Allergic Sensitization to Spatially Unlinked Antigen"
9:15 pm - 9:20 pm	Discussion
9:20 pm - 9:30 pm	General Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Food Allergy Prevention and Early Immunity Discussion Leader: Elise Liu (Yale University School of Medicine, United States)
9:00 am - 9:05 am	Introduction by Discussion Leader
9:05 am - 9:40 am	Kari Nadeau (Stanford University, United States) "Mechanisms of Prevention of Food Allergy"
9:40 am - 9:45 am	Discussion
9:45 am - 9:50 am	Introduction by Discussion Leader
9:50 am - 10:00 am	Courtney Jackson (University of Rochester Medical Center, United States) "Early Life Influences on Developing Human B Cell Immunity"
10:00 am - 10:05 am	Discussion
10:05 am - 10:15 am	Catherine Pizzarello (School of Medicine and Dentistry, University of Rochester, United States) "Effector Memory CD25+CD127+ T Cells with a Highly Skewed Th2 Phenotype are an Early Marker in Infancy for the Risk of Allergic Disease"
10:15 am - 10:20 am	Discussion
10:20 am - 10:30 am	Lauren Hesser (University of Chicago, United States) "Developing a Synbiotic Biotherapy to Prevent Allergic Responses to Food"
10:30 am - 10:35 am	Discussion
10:35 am - 10:45 am	Sloan Lewis (La Jolla Institute for Immunology, United States) "Identification and Characterization of Allergen-specific T Cells in Pediatric Cow’s Milk Allergy"
10:45 am - 10:50 am	Discussion
10:50 am - 11:00 am	General Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Career Considerations in Basic Translational Food Allergy Research Discussion Leader: Maria Curotto de Lafaille (Icahn School of Medicine at Mount Sinai, United States)
1:30 pm - 2:30 pm	Panel Discussion Career Considerations in Translational Food Allergy Research Simon Hogan (University of Michigan, United States) Jamie Orengo (Regeneron Pharmaceuticals, United States) Kari Nadeau (Stanford University, United States)
2:30 pm - 3:00 pm	Evaluation Period Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm	Seminar Concludes

Contributors

Food Allergy Research and Education

Research reported in this publication was supported by the National Institute Of Allergy And Infectious Diseases of the National Institutes of Health under Award Number R13AI164747. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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