Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Immune Basis of Allergy and Tolerance to Foods
Discussion Leader: Sarita Patil (Massachusetts General Hospital / Harvard Medical School, United States)
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:15 pm
Cecilia Berin (Northwestern University, United States)
"T Cells in the Pathophysiology of Food Allergy"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Current Advances in Understanding Innate and Mucosal Immunity in Food Allergy
Discussion Leaders: DeBroski Herbert (University of Pennsylvania, United States) and Michiko Oyoshi (Massachusetts General Hospital / Harvard University, United States)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:45 pm
Jamie Blum (Stanford University/HHMI, United States)
"Contribution of Plant Metabolites to Allergy and Oral Tolerance"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:00 pm
Elena Christian (Massachusetts General Hospital, United States)
"Plant Defense Compounds Control a Neuro-Immune Circuit in Allergic Sensitization"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:15 pm
Armando Puente (University of Chicago, United States)
"Modulation of Immunity by Commensal Flagellin"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
Allison Kosins (Indiana University School of Medicine, United States)
"Maternal Supplementation With Alpha-Tocopherol Inhibits the Development of Food Allergy Early in Life"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Haoran Gao (Indiana University School of Medicine, United States)
"Depletion of Eosinophil with Diphtheria Toxin Blocks the Development of Food Allergy Early in Life"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
Jennifer Li (Massachusetts General Hospital, United States)
"Evaluation of Intestinal Permeability and T Cell Responses in Double-Blind Placebo-Controlled Oral Food Challenges"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:15 pm
Nandinee Patel (Imperial College London, United Kingdom)
"The Effect of Treatment Duration on Efficacy During OIT Using Heat-Modified Peanut - Results from the BOPI Study"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Adaptive Immune Response in Food Allergy
Discussion Leader: Kirsi Jarvinen-Seppo (University of Rochester Medical Center, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:15 am
Cameron Flayer (Massachusetts General Hospital, United States)
"A gd T Cell-IL-3 Axis Controls the Responsiveness of Sensory Neurons to Allergens."
9:15 am - 9:20 am
Discussion
9:20 am - 9:30 am
Magdalena Kraft (Northwestern University, United States)
"Humoral Immune Responses Induced by Venom are Tfh Cell-Dependent."
9:30 am - 9:35 am
Discussion
9:35 am - 9:45 am
Pooja Kher (ASU, United States)
"Examining the Behavioral and Immunological Phenotypes for Type II Inflammation in Food Allergy Model"
9:45 am - 9:50 am
Discussion
9:50 am - 10:00 am
Orlee Marini-Rapoport (Massachusetts General Hospital, United States)
"Defining Ara h 2 and Ara h 6 Cross-Reactivity Using Monoclonal Antibodies"
10:00 am - 10:05 am
Discussion
10:05 am - 10:15 am
Warren Blackmon (Baylor College of Medicine, United States)
"Characterizing the gd T Cell Immune Response of Shrimp Allergic Peripheral Blood Mononuclear Cells After Major Allergen Tropomyosin Stimulation"
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Bin Brenda Su (Baylor College of Medicine, United States)
"Identification of Single Cell RNA Signature Immune-Related Pathways in Gamma Delta (GD)T Cells in Shrimp Allergy"
10:30 am - 10:35 am
Discussion
10:35 am - 10:45 am
Jennifer Styles (UNC-CH, United States)
"Immunomodulatory Metabolites Differ Over Time and Between Desensitization Outcomes in Children on Peanut Oral Immunotherapy"
10:45 am - 10:50 am
Discussion
10:50 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Translational Research in Allergy
Discussion Leader: Eric Wambre (Mount Sinai Hospital, United States)
1:30 pm - 1:40 pm
Carlos Bosques (Food Allergy Science Initiative, United States)
"Introductions to Panel Discussion on Careers in Food Allergy Research"
1:40 pm - 1:45 pm
Discussion
1:45 pm - 2:30 pm
Panel Discussion
Careers in Food Allergy Research
Amina Abdul Qayum (Industry, United States)
Yamini Virkud (University of North Carolina, United States)
Derek Croote (IgGenix, United States)
Geoffrey Mueller (National Institute of Environmental Health Sciences, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes