Conference Description
The Genome Architecture in Cell Fate and Disease GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
In the past decades, we have witnessed rapid research progress in deciphering the fundamental mechanisms governing the 3-dimensional organization of eukaryotic genomes within the nucleus and their roles in gene expression, genome stability and cell division. Understanding such principles provides deeper insights into normal development and physiology, and their deregulation in disease. Ongoing efforts aim to improve the resolution of analyses towards single cells and multi-dimensions to reveal the systems-level complexity in gene regulation. As a result, the rich information encoded in the complex gene regulation through space and time is being uncovered. How to harness such information to advance the knowledge of our genome and to achieve disease treatment remains a challenging task. The 2025 conference on Genome Architecture in Cell Fate and Disease: “Probing and Controlling Gene Regulation in Space and Time” is the fifth meeting of this series that aims to inspire discussion in the field of 3D genome organization. Specific focus will be placed on mechanisms of genome organization, gene regulation in development, 3D genome in fundamental processes such as DNA replication and repair, chromatin dysfunction in disease, technology development, data integration and modelling.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by February 15, 2025. Please check back for updates.
Genome Architecture and Gene Regulation
Discussion Leaders
Speakers
Principles of 3D Genome Folding
Discussion Leaders
Speakers
Genome Architecture, DNA Repair and Cell Division
Discussion Leaders
Speakers
Modelling and Predicting Chromatin Structure and Function
Discussion Leaders
Speakers
Chromatin Structure in Time and Space
Discussion Leaders
Speakers
Chromatin Dynamics and Engineering of Regulatory Mechanisms
Discussion Leaders
Speakers
Chromatin Regulation in Development and Differentiation
Discussion Leaders
Speakers
Chromatin Regulation in Health and Disease
Discussion Leaders
Speakers
Functional Genomics
Discussion Leaders
Speakers
The GRC Power Hour™
Organizers
