Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Genome Architecture in Cell Fate and Disease
Discussion Leader: Joyce Thompson (NICHD/NIH, United States)
3:45 pm - 4:15 pm
Jennifer Philips-Cremins (UPenn, United States)
"Dissection of the Genome’s Structure-Function Relationship in the Mammalian Brain"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Molecular Mechanisms and Functions of Genome Architecture
Discussion Leader: Tessa Popay (Salk Institute for Biological Studies, United States)
7:30 pm - 7:50 pm
Hocine Rekaik (EPFL, Switzerland)
"A Dynamic and Mechanistic View of Chromatin Changes During the Hox Timer in Pseudo-Embryos"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Kim de Luca (Hubrecht Institute, The Netherlands)
"Genome-Wide Profiling of DNA Repair Identifies Higher-Order Coordination in Single Cells"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Zhenhai Du (Tsinghua University, China)
"Stepwise De Novo Establishment of the Architecture of the Inactive X Chromosome during Early Development"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Pia Mach (Friedrich Miescher Institute for Biomedical Research, Switzerland)
"Cohesin and CTCF Control the Dynamics of Chromosome Folding"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Novel Approaches Exploring Genome Architecture
Discussion Leader: Cheuk Yin CHENG (The Hong Kong University of Science and Technology, Hong Kong SAR China)
9:00 am - 9:20 am
Mark Pownall (Yale University School of Medicine, United States)
"Chromatin Expansion Microscopy Reveals Nanoscale Organization of Transcription and Chromatin"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Madhoolika Bisht (The Ohio State University, United States)
"CRISPR-Based Live Cell Imaging Reveals Chromosome Territory Deformation in Osteosarcoma"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Hannah Richter (Gladstone Institutes, United States)
"Visualizing the Chromatin Landscape of Differentiation at Single-Fiber Resolution"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Miao Liu (Yale University, United States)
"Genome-wide Chromatin Tracing Reveals Three-Dimensional Genome Reorganization During Lung Cancer Progression"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Development
Discussion Leader: Jia WANG (Guangzhou Medical University, China)
1:30 pm - 2:30 pm
Panel Discussion
Navigating Career Paths
Jennifer Philips-Cremins (UPenn, United States)
Wei Xie (Tsinghua University, China)
Tiago Faial (Nature Genetics, United States)
Rita Rozmarynowycz (Arima Genomics, United States)
Maria Cristina Gambetta (University of Lausanne, Switzerland)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
