Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Keynote Session: Metabolic Pathways in Modulation of Germ Cell Activity
Discussion Leader: Myles Bartholomew (Brown University, United States)
3:15 pm - 3:20 pm
Introduction by Discussion Leader
3:20 pm - 3:50 pm
Tessa Lord (University of Newcastle, Australia)
"Exploring the Intersection Between Regulation of Metabolism and Spermatogonial Stem Cell Function"
3:50 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Pathways in Controlling and Effecting the Germline
Discussion Leader: Kathleen Stewart-Morgan (University of Copenhagen, Denmark)
5:30 pm - 5:50 pm
Tom Mattimoe (Centre for Genomic Regulation, Spain)
"Interrogating the Importance of X-Chromosome Inactivation and Reactivation for Meiotic Potential"
5:50 pm - 6:00 pm
Discussion
6:00 pm - 6:20 pm
Marion Salzer (Center for Genomic Regulation, Spain)
"Primordial Oocytes Display Low Susceptibility to Aging"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
Pranay Shah (MRC Laboratory of Molecular Biology, United Kingdom)
"DNA Translesion Synthesis Factors are Essential for Mouse and Human Germ Cell Development"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
Xinyan Yang (Southern Medical University, China)
"Human Spermatogenesis and Male Infertility"
7:20 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
In Vitro Germline Development
Discussion Leader: Arend Overeem (Leiden University Medical Centre, The Netherlands)
9:00 am - 9:20 am
Yolanda Chang (Leiden University Medical Center, The Netherlands)
"In Vitro Maturation of Human Primordial Germ Cell-like Cells (hPGCLCs) in the Female Human Somatic Niche"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Linzi Ma (Southern Medical University, China)
"Lovastatin Promotes the Self-renewal of Murine and Primate Spermatogonial Stem Cells"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Aly Makhlouf (MRC Laboratory of Molecular Biology, United Kingdom)
"Basement Membrane Signaling Restricts Entry into the Germline"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Merrick Pierson Smela (Harvard University, United States)
"Transcription Factor Mediated Differentiation of Human iPSCs to Oogonia-like and Ovarian Granulosa-like Cells"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Transitioning to Junior Faculty in the Current Academic Research Climate
Discussion Leader: Lessly Sepulveda-Rincon (Imperial College London, United Kingdom)
1:30 pm - 1:35 pm
Introduction by Discussion Leader
1:35 pm - 2:30 pm
Panel Discussion
Pathways to Success as a Modern PI
Patrick Allard (University of California, Los Angeles, United States)
Namya Mellouk (INRAE, France)
Sue Hammoud (University of Michigan, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes