SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Roles of Glia in Synapse Development |
| Discussion Leader: Brian MacVicar (University of British Columbia) |
7:40 pm - 8:10 pm | Ben Barres (Stanford University) "Glial Control of Synaptic Glutamate Responsiveness" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:45 pm | Beth Stevens (Children’s Hospital/Harvard University) "Pruning CNS Synapses: An Unexpected Role for Glia and Proteins of the Innate Immune System" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Angelique Bordey (Yale University) "Function of subventricular zone astrocytes on postnatal neurogenesis" |
9:20 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Behavioral and Circuit Roles for Astrocytes |
| Discussion Leader: Bruce Ransom (University of Washington) |
9:00 am - 9:25 am | Pierre Magistretti (Ecole Polytechnique Fedrale de Lausanne (EPFL) "Neuron-glia metabolic plasticity: functional implications" |
9:25 am - 9:30 am | Discussion |
9:30 am - 9:55 am | Hajime Hirase (Riken) "Astrocytic modulation of sensory-evoked LFP response" |
9:55 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:00 am | C. Justin Lee (Korean Institute of Science and Technology (KIST)) "Channel-mediated tonic GABA release from glia" |
11:00 am - 11:05 am | Discussion |
11:05 am - 11:35 am | Frank Kirchoff (Max Planck Institute) "Genetic Mouse Models and Imaging Approaches to Study Neuron-glia Interactions In Vivo" |
11:35 am - 11:40 am | Discussion |
12:00 pm - 12:10 pm | Trainee Presentation I: Nicola Allen (Stanford University) "Identification of an astrocyte-secreted protein that is sufficient to induce active synapse formation" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Trainee Presentation II: Dustin Hines (Tufts University School of Medicine) "Anti-depressive effects of sleep deprivation require the astrocyte-dependent sleep-homeostat" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Roles for Glia in disorders of the nervous system |
| Discussion Leader: Pierre Magistretti (EPFL) |
7:30 pm - 8:00 pm | Jeffrey Rothstein (Johns Hopkins - Brain Science Institute) "Astrocyte dysfunction in neurodegenerative disease" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Mike Salter (University of Toronto) "Microglia and neuropathic pain" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Maiken Nedergaard (University of Rochester) "Astrocyte Calcium Imaging and Diseases of the Central Nervous System" |
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Roles of Microglia in Disorders of the Brain |
| Discussion Leader: Vlad Parpura (University of Alabama Birmingham) |
9:00 am - 9:30 am | Joseph El-Khoury (Harvard Medical School) "Chemokines and regulation of neuron-microglial interactions" |
9:30 am - 9:35 am | Discussion |
9:35 am - 10:05 am | Harold Neumann (University Bonn) "Role of microglial ITAM/ITIM signaling receptors in neurodegeneration and repair" |
10:05 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:40am - 11:10 am | Marco Prinz (University of Freiburg) "Microglia in pathophysiology" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:45 am | Richard Ransohoff (Cleveland Clinic) "Monocytes, macrophages and microglia: New light from fluorescent markers?" |
11:45 am - 11:50 am | Discussion |
12:00 pm - 12:10 pm | Trainee Presentation I: Christopher Parkhurst (NYU School of Medicine) "Generation and characterization of a CX3CR1-CreER mouse for the study of microglial function in the CNS" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Trainee Presentation II: Susan Buckingham (University of Alabama at Birmingham) "Glutamate Release by Glioma Cells Induces Peritumoral Seizures" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Functions of Glial Connexins and Pannexins |
| Discussion Leader: Gerald Dienel (University of Arkansas) |
7:30 pm - 8:00 pm | Steve Scherer (University of Pennsylvania) "How Mutations in Gap Junctions Cause Glial Diseases" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | David Spray (Albert Einstein College of Medicine) "Connexins, Pannexins and ATP" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Christian Giaume (INSERM) "Amyloid β-induced neuronal death involves glial and neuronal hemichannel activation cascade" |
9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Synapse-Glial Interactions |
| Discussion Leader: Andrea Volterra (Universite de Lausanne) |
9:00 am - 9:30 am | Baljit Khakh (University of California Los Angeles) "Compartmentalized Ca2+ signaling" |
9:30 am - 9:35 am | Discussion |
9:35 am - 10:05 am | Dwight Bergles (Johns Hopkins) "In vivo imaging of NG2+ cell behavior" |
10:05 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:40 am - 11:10 am | David Attwell (University College London) "Control of myelination by neurotransmitters" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:45 am | Sergey Kasparov (University of Bristol) "New insights into the roles of astrocytes in cardio-respiratory control" |
11:45 am - 11:50 am | Discussion |
12:00 pm - 12:10 pm | Trainee Presentation I: Clare Howarth (University of British Columbia) "Modulation of astrocyte PgE2 synthesis and the impact on vascular control" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Trainee Presentation II: Kira Poskanzer (Columbia University) "An astrocytic mechanism of UP state generation" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | Control of the Vasculature by Glial Cells |
| Discussion Leader: Tailoi Chan-Ling (University of Sydney) |
7:30 pm - 8:00 pm | Eric Newman (University of Minnesota) "Glial regulation of blood flow in the normal and diabetic retina" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Brian MacVicar (University of British Columbia, Canada) "Astrocyte control of cerebral blood vessels in health and disease" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Serge Charpak (INSERM) "Simultaneous two-photon measurements of pre- and postsynaptic activity, blood flow and oxygen in the central nervous system" |
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Astrocytic Modulation of Synaptic Plasticity |
| Discussion Leader: Helmut Kettenmann (Max Delbruck Center for Molecular Medicine) |
9:00 am - 9:30 am | Ken McCarthy (University of North Carolina) "Genetic Analysis of the role of astrocytic GPCRs in physiology and behavior" |
9:30 am - 9:35 am | Discussion |
9:35 am - 10:05 am | Andrea Volterra (Universite de Lausanne) "Local Ca2+ detection of synaptic release by astrocytes and control of glutamatergic gliotransmission by TNFalpha" |
10:05 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:40 am - 11:10 am | Jaideep Baines (University of Calgary) "Glial dependent synaptic scaling" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:45 am | Stephane Oliet (INSERM) "Contribution of glial D-serine to NMDA receptor activity" |
11:45 am - 11:50 am | Discussion |
12:00 pm - 12:10 pm | Trainee Presentation I: Kathryn Reissner (Medical University of South Carolina) "Glia GLT-1 is required for inhibition of cocaine seeking by N-acetylcysteine" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Trainee Presentation II: Bruno Benedetti (Cellular Neuroscience) "Astrocytes control GABAergic inhibition of neurons in the mouse barrel cortex" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Epilepsy and Glia |
| Discussion Leader: Harald Sontheimer (University of Alabama Birmingham) |
7:30 pm - 8:00 pm | Douglas Coulter (Children’s Hospital of Philadelphia) "Regulation of hippocampal excitability by the astrocytic glutamine cycle" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Giorgio Carmignoto (University of Padova) "Astrocyte signalings in generation and propagation of focal seizures" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Detlev Boison (RS Dow Neurobiology Laboratories) "Glial dysfunction of adenosine signaling in epilepsy" |
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |