Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Astrocyte Contribution to Synapse Structure and Function
Session in memory of Ben Barres.
Discussion Leaders: Erik Ullian (University of California, San Francisco, USA) and Tracy Yuen (Genentech, Inc., USA)
7:40 pm - 8:00 pm
Keith Murai (McGill University, Canada)
"Astrocyte Interactions with Neuronal and Synapse Microenvironments in the Brain"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Carlos Paladini (University of Texas at San Antonio, USA)
"Ventral Tegmental Area Astrocytes Orchestrate Avoidance and Approach Behavior"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Paola Bezzi (University of Lausanne, Switzerland)
"Astrocytic mGluR5 Controls Postnatal Maturation of Astrocytes and of Associated Synapses"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Cagla Eroglu (Duke University Medical Center, USA)
"How Do Glia Sculpt Synaptic Circuits?"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Glial Control of Circuit Function
Discussion Leaders: Nathalie Rouach (College de France, France) and Harald Sontheimer (School of Neuroscience, Virginia Tech, USA)
9:00 am - 9:20 am
Maiken Nedergaard (University of Copenhagen, Denmark / University of Rochester, USA)
"Astrocytic Functions Differ Depending on Brain State"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Misha Ahrens (Howard Hughes Medical Institute, USA)
"A Role for Astroglia in Shaping the Behavior of Larval Zebrafish"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Inbal Goshen (Hebrew University of Jerusalem, Israel)
"Activity-Dependent and Projection-Specific Effects of Astrocytes on Plasticity and Memory"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Philip Haydon (Tufts University, USA)
"Sleep and Wake Coordinated by Glia"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Hajime Hirase (RIKEN Center for Brain Science, Japan)
"Astrocytic GPCR Activation in Behaving and Stroke Mice"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Kira Poskanzer (University of California, San Francisco, USA)
"Optically Decoding Cortical Astrocyte Circuits"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
Organizers: Kelly Monk (Vollum Institute, USA) and Paola Bezzi (University of Lausanne, Switzerland)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Molecular Diversity of Glia
Discussion Leaders: Michelle Monje (Stanford University, USA) and Michael Sofroniew (University of California, Los Angeles, USA)
7:30 pm - 7:50 pm
Baljit Khakh (University of California, Los Angeles, USA)
"Regional, Local and Functional Diversity of Striatal Astrocytes"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Goncalo Castelo-Branco (Karolinska Institutet, Sweden)
"Transcriptional and Epigenetic States of Oligodendrocyte Lineage Cells During Development and in Multiple Sclerosis"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Jiaqian Wu (McGovern Medical School, University of Texas Health Science Center at Houston, USA)
"Dissecting the Heterogeneity of Reactive Astrocytes in the CNS to Drive New Insights into Disorders"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
David Rowitch (University of Cambridge, United Kingdom)
"Understanding Functional Diversity of Astrocytes"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Glial Control of Neuronal Excitability
Discussion Leaders: Susan Campbell (Virginia Tech, USA) and Bruce Ransom (University of Washington School of Medicine, USA)
9:00 am - 9:20 am
Aiman Saab (University of Zurich, Switzerland)
"Axon-Glial Interactions Regulating Axonal Energy Metabolism"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Michelle Olsen (Virginia Tech, USA)
"A Role for Astrocytic Ion Channels in the Control of Breathing"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
David Attwell (University College London, United Kingdom)
"The Role of Pericytes and Microglia in Early Alzheimer's Disease"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Yihui Cui (Zhejiang University, China)
"Astroglial Kir4.1 in the Lateral Habenula Drives Neuronal Bursts to Mediate Depression"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Maarten Kole (Netherlands Institute for Neuroscience (NIN-KNAW), The Netherlands)
"Disentangling the Axon-Myelin Circuit for Saltatory Conduction"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Gertrudis Perea (Cajal Institute, CSIC, Spain)
"Interneuron-Astrocyte Dialog Regulates GABAergic Transmission in Cortical Circuits"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Glial Involvement in Neurodegenerative Disease
Discussion Leader: Beth Stevens (Boston Children's Hospital, USA)
7:30 pm - 7:50 pm
Katerina Akassoglou (Gladstone Institutes / University of California, San Francisco, USA)
"Fibrinogen Modulation of Glial Reactivity and Regeneration"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Giles Hardingham (University of Edinburgh, United Kingdom)
"How Do Neurons and Glia Control Each Other's Transcriptomes, and What Are the Consequences?"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Elly Hol (Brain Center, UMC Utrecht, The Netherlands)
"Role of Reactive Astrocytes in Synapse Dysfunction and Cognitive Impairment"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Jonathan Kipnis (University of Virginia, USA)
"Peripheral Immunity-Glia Interaction in Neurophysiology"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Glia and Neuromodulation
Discussion Leaders: Alfonso Araque (University of Minnesota, USA) and Serge Charpak (Paris Descartes University, France)
9:00 am - 9:20 am
Matthew Holt (VIB-KU Leuven Center for Brain and Disease Research, Belgium)
"Molecular Heterogeneity of Astrocytes: Potential Implications for Development and Function"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Arlette Kolta (University of Montreal, Canada)
"Astroglial Modulation of Na+ Channels: A Ubiquitous Mechanism to Regulate Neuronal Firing"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Andrea Volterra (University of Lausanne, Switzerland)
"Further Insight on the Mechanisms of Synapse-Astrocyte Communication in the Hippocampal Dentate Gyrus"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Naveen Nagarajan (University of Utah, USA)
"Corticostriatal Circuit Defects in Hoxb8 Mouse Model of Repetitive Behaviors"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Anna Dunaevsky (University of Nebraska Medical Center, USA)
"Modulation of Astrocyte Ca2+ Signaling with Movement and Motor Skill Learning"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Alexander Gourine (University College London, United Kingdom)
"Astroglial Control of Autonomic Circuits"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Development of Glia
Discussion Leaders: Sarah Kucenas (University of Virginia, USA) and David Lyons (University of Edinburgh, United Kingdom)
7:30 pm - 7:50 pm
Freda Miller (The Hospital for Sick Children, Canada)
"Growth Factors and Regulation of the Neural Precursor to Oligodendrocyte Transition"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Shai Shaham (The Rockefeller University, USA)
"Astroglial Control of C. elegans Behavior"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Vittorio Gallo (Children's National Health System, USA)
"Oligodendrocyte Development and Regeneration in the Early Postnatal Brain"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Fiona Doetsch (Biozentrum, University of Basel, Switzerland)
"Glial Diversity in the Adult Neural Stem Cell Niche"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
New Methods for Visualizing and Manipulating Glia
Discussion Leader: Ko Matsui (Tohoku University, Japan)
9:00 am - 9:20 am
Christine Rose (Heinrich Heine University Düsseldorf, Germany)
"Visualizing and Manipulating Glial Sodium"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Michael Bruchas (University of Washington, USA)
"Optical Control of GPCR Signaling"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Frank Kirchhoff (Saarland University, Germany)
"Linking Glial Ca2+ Signals with CNS Functions"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Jin Zhang (University of California, San Diego, USA)
"Fluorescent Biosensors for Illuminating the Biochemical Activity Architecture of the Cell"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Mary Logan (Oregon Health and Science University, USA)
"Genetic Investigation of Innate Glial Immune Activity"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Louis-Philippe Bernier (University of British Columbia, Canada)
"Brain Pericytes Are Mesenchymal Progenitors that Support Cerebrovascular Regeneration After Stroke"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Katie Yergert (University of Colorado Anschutz Medical Campus, USA)
"Neural Activity Modulates mRNA Localization and Protein Expression Within Nascent Myelin Sheaths"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Satellite Glial Cells
Discussion Leaders: Menachem Hanani (Hadassah University Hospital, Israel) and Helmut Kettenmann (Max Delbruck Center for Molecular Medicine, Germany)
7:30 pm - 7:50 pm
Jaeda Coutinho-Budd (University of Vermont, USA)
"Exploring Neuron-Glia Interactions at Neuronal Cell Bodies"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Randy Blakely (Florida Atlantic University, USA)
"Glial Support for Dopamine Neuron Activity, Behavioral Actions and Survival: The Worm's Turn"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Valeria Cavalli (Washington University in St. Louis, USA)
"Functional Role of Satellite Glial Cells in Axon Regeneration"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Xinzhong Dong (Johns Hopkins University School of Medicine, USA)
"The Contribution of Satellite Glial Cells to Pain"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure