Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Glial Interactions with Axons and Synapses
7:40 pm - 8:00 pm
"Neuron-Glia Signaling in the Developing Nervous System"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Myelin Plasticity in Health and Disease"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
"Diversity of Mechanisms in Myelination"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Microglia-Astrocyte Communication at the Synapse"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Glial Interactions in Circuit Formation
9:00 am - 9:20 am
"Astrocyte Regulation of Neuronal Synapses"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Phagocytic Roles of Astrocytes in Synapse Elimination"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Dynamic Regulation of Neuron-Glia Lipid Trafficking in the Developing Drosophila Brain"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Inhibitory Input Drives Astrocyte Morphogenesis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Functions of glial cells in coordinating neuronal aging"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Alternative Translation of Astrocyte Aqp4 Promotes Waste Clearance from the Brain"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
CNS Interactions with the Periphery Through Glia
7:30 pm - 7:50 pm
"Livin' on the Edge: The role of Glial-Glial Interactions at the Nervous System Transition Zones in Development and Disease"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Neuro-Vascular Interactions in the CNS"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Blood-Brain Barrier in Health and Disease"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Choroid Plexus Contributions to CSF Composition and Brain Function"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Ensheathment and Myelination of Axons
9:00 am - 9:20 am
"Studying Myelinated Axons in Vivo Using Zebrafish"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Neuron-Glia Interactions Orchestrating Myelin Regeneration"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Striatins Connect Rac1 and Hippo Signaling and are Essential for Peripheral Myelination"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"The Dynamic Role of Glal Cells in Acquired and Inherited Demyelinating Disease"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Compartment-specific astrocyte and neuron subproteomes"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Oligodendrocytes and myelin restrict experience-dependent neuronal plasticity in the visual cortex"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"An Fbxw7/Myrf axis regulates the extent of myelination in the CNS"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Glial Functions in Disease Pathology
7:30 pm - 7:50 pm
"Microglia-Synapse Interactions in Disease Pathology"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Neuroprotective Function of Microglial TREM2 Against TDP-43 Neurodegeneration"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Cell Competition Sustains the Fountain of Youth for OPCs: Robustness and Hidden Dangers"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Microglia Mediate the Neurobiological Effects of Chronic Stress"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Myeloid and Reactive Cells in the Brain
9:00 am - 9:15 am
"Uncovering the Role of Glia in Neurodegeneration One Image at a Time"
9:15 am - 9:25 am
Discussion
9:25 am - 9:45 am
"Perineuronal nets support astrocytic ion and glutamate homeostasis at tripartite synapses"
9:45 am - 9:55 am
Discussion
9:55 am - 10:15 am
"The Role of Reactive Astrocytes in Inflammation and Neurodegeneration"
10:15 am - 10:25 am
Discussion
10:25 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
"Neuron-microglia Crosstalk in Development: a Novel Role for Neuron-Derived Cytokine IL34 in Microglial Function"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Microglia-Astrocyte Communication at the Synapse"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"How Do Glial Remodel the Nervous System?"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Astrocyte to Microglia Signaling Controls to Balance Between Synapse Formation and Elimination"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Effects of Myelin Distribution on Ayonal Conduction"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Control of Neuronal Environment by Glia
7:30 pm - 7:45 pm
"Myelin Lipids as a Nervous System Energy Source"
7:45 pm - 7:55 pm
Discussion
7:55 pm - 8:10 pm
"Glia-Neuron Metabolic Interactions in Drosophila: Lactate and Beyond"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Glial contributions to neurovascular dysregulation after ischemic injury"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"A biochemical circuit spanning neurons and astrocytes implements feed-forward inhibition during futility-induced passivity"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Astrocytes mediate the effect of norepinephrine at excitatory synapses"
8:55 pm - 9:00 pm
Discussion
9:10 pm - 9:20 pm
"Astrocyte to Microglia Signaling Controls the Balance Between Synapse form Thin and Elimination"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:35 pm
"Effects of Myelin Distribution on Axonal Conduction"
9:35 pm - 9:40 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Glial Regulation of Neural Activity and Connectivity
9:00 am - 9:20 am
"Transcriptionally Defined Cell Types can be Morphologically Diverse"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Microglial Function and Dysfunction in the Early Postnatal Brain"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Genetic Toolkits to Dissect Myelination in Vivo"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Astrocytes: Guardians of Critical Period Plasticity in the Visual Cortex"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"How do Microglia Shape Circuit Formation?"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Local caspase activity regulates complement-dependent synaptic phagocytosis by microglia"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Oligodendrocyte precursor cells engulf synapses in an experience- and microglia-dependent manner"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Glial Regulation of Complex Disorders
7:30 pm - 7:50 pm
"Where, When and How: Astrocytic Regulation of Post-Stroke Plasticity"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Glial Functions During Innate Spinal Cord Repair"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"The Role of Non-Neuronal Cell Types in Autism Spectrum Disorders"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Identification of microglial cannibalism reveals a paradox that shortens the lifespan of developmental microglia"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Investigating the role of glial KCNR Kt Channels in Neuronal C. Elegons"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure