SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Check-in Desk Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 8:15 pm | Keynote Speaker |
7:40 pm - 8:05 pm | Lawrence Tabak (Principal Deputy Director, NIH)
"Translating the Third Language of Life" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 9:30 pm | Glycan Engineering and Stem Cells |
8:15 pm - 8:19 pm | Discussion Leader: Robert Sackstein (Harvard Medical School) |
8:19 pm - 8:40 pm | Jamey Marth (Sanford-Burnham Medical Research Institute)
"Applications of Bioengineering and Nanotechnologies to Glycobiology" |
8:40 pm - 8:48 pm | Discussion |
8:48 pm - 9:09 pm | James Paulson (The Scripps Research Institute)
"Targeting immune cells with siglec ligands" |
9:09 pm - 9:17 pm | Discussion |
9:17 pm - 9:25 pm | Poster Presenter: Naoyuki Taniguchi (Riken Advanced Science Institute)
"Regulation of Brain-Specific GnT-IX (Vb) Expression by Neural Histone-Code" |
9:25 pm - 9:29 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Glycan Engineering and Stem Cells (continued) |
9:00 am - 9:02 am | Discussion Leader: Robert Sackstein (Harvard Medical School) |
9:02 am - 9:23 am | Lai-Xi Wang (University of Maryland School of Medicine)
"Chemoenzymatic Glycosylation Engineering of Glycoproteins" |
9:23 am - 9:30 am | Discussion |
9:30 am - 9:51 am | Mike Tiemeyer (University of Georgia)
"Stem Cell Glycomics" |
9:51 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break / Group Photo |
10:30 am - 10:50 am | Catherine Merry (University of Manchester)
"Using glycosaminoglycan saccharides to control stem cell behaviour" |
10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Glycans in Cancer |
11:00 am - 11:04 am | Discussion Leader: James Dennis (Samuel Lunenfeld Research Institute) |
11:04 am - 11:25 am | Hisashi Narimatsu (National Institute of Advanced Industrial Science and Technology - AIST)
"Development of diagnosis kit for liver fibrosis and liver cancer" |
11:25 am - 11:32 am | Discussion |
11:32 am - 11:53 am | Frederic Bard (Institute for Molecular and Cell Biology, Singapore)
"The Sweet Tooth of Src: Regulation of O-glycosylation Through Enzyme Trafficking" |
11:53 am - 12:01 pm | Discussion |
12:01 pm - 12:09 pm | Poster Presenter: Konstantinos Konstantopoulos (John Hopkins University)
"Sialofucoyslated Podocalyxin-like protein is a Functional E-/L Selectin Ligand Expressed in Metastatic Tumor Cells" |
12:09 pm - 12:13 pm | Discussion |
12:13 pm - 12:21 pm | Poster Presenter: Tadashi Suzuki (Riken Advanced Science Institute)
"Role of Autophagy in the Catabolism of Sialylated Oligosaccharides in Mammalian Cells" |
12:21 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | Chair Time |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | Developmental Glycobiology |
5:30 pm - 5:34 pm | Discussion Leader: Pamela Stanley (Albert Einstein College of Medicine) |
5:34 pm - 5:55 pm | Robert Haltiwanger (Stony Brook University)
"Role of Glycosylation in Notch Signaling" |
5:55 pm - 6:03 pm | Discussion |
6:03 pm - 6:24 pm | Hannes Buelow (Albert Einstein College of Medicine)
"A Role for Specific Heparan Sulfate Modifications in Neural Development" |
6:24 pm - 6:32 pm | Discussion |
6:32 pm - 6:53 pm | Kelly Ten Hagen (NIH / INDCR)
"The Role of Mucin-type O-glycosylation in Secretion, Cell Adhesion and Organ Formation" |
6:53 pm - 7:01 pm | Discussion |
7:01 pm - 7:09 pm | Poster Presenter: Hideyuki Takeuchi (Stony Brook University)
"Novel Specificity of a Glycosyltransferase, Rumi, Toward Epidermal Growth Factor Repeats" |
7:09 pm - 7:13 pm | Discussion |
7:13 pm - 7:21 pm | Poster Presenter: David Live (University of Georgia)
"Does POMGnT1 Activity Influence Man-6 P04 Glycans of α Dystroglycan?" |
7:21 pm - 7:25 pm | Discussion |
7:25 pm - 7:30 pm | Chair Time |
8:00 pm | Dinner |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Glycans in Physiology |
9:00 am - 9:03 am | Discussion Leader: Jeffrey Esko (University of California, San Diego) |
9:03 am - 9:24 am | Jeffrey Esko (University of California, San Diego)
"Proteoglycans, Receptors That Mediate Uptake of High Molecular Weight Cargo" |
9:24 am - 9:32 am | Discussion |
9:32 am - 9:53 am | Jacques Baenziger (Washington University Medical School)
"Making Bambinos Requires the Right Sugars" |
9:53 am - 10:30 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:52 am | Ajit Varki (University of California, San Diego)
"Uniquely Human Aspects of Glycobiology" |
10:52 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Glycosylation Disorders and Therapy |
11:00 am - 11:04 am | Discussion Leader: Thierry Hennet (University of Zürich) |
11:04 am - 11:26 am | Fumi Irie (Sanford-Burnham Medical Research Institute)
"Heparan Sulfate and the Brain" |
11:26 am - 11:33 am | Discussion |
11:33 am - 11:56 am | Kevin Campbell (Howard Hughes Medical Institute)
"Molecular Basis of Glycosylation-deficient Muscular Dystrophy and Approaches to Therapy" |
11:56 am - 12:02 pm | Discussion |
12:02 pm - 12:25 pm | Ronald Schnaar (The Johns Hopkins School of Medicine)
"Gangliosides in Axon-myelin Interactions" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | Glycans in Metabolism and Signaling |
5:30 pm - 5:34 pm | Discussion Leader: Gerald Hart (The Johns Hopkins School of Medicine) |
5:34 pm - 5:55 pm | Dona Love (NIH / NIDDK)
"Epigenetic Regulation of the Transcriptional Machinery by O-GlcNAc Cycling" |
5:55 pm - 6:03 pm | Discussion |
6:03 pm - 6:24 pm | Richard Cummings (Emory University School of Medicine)
"Roles of Glycans in Platelet and Leukocyte Adhesion and Signaling" |
6:24 pm - 6:32 pm | Discussion |
6:32 pm - 6:53 pm | James Dennis (Samuel Lunenfeld Research Institute)
"N-glycan Processing, Metabolism and Adaptation at the Cell Surface" |
6:53 pm - 7:01 pm | Discussion |
7:01 pm - 7:09 pm | Poster Presenter: John A. Hanover (NIDDK, NIH)
"O-GlcNAc and Epigenetics" |
7:09 pm - 7:13 pm | Discussion |
7:13 pm - 7:21 pm | Poster Presenter: Thorsten Marquardt (University Hospital Muenster)
"Disease of the Translocon: SSR3 Deficiency" |
7:21 pm - 7:25 pm | Discussion |
7:25 pm - 7:30 pm | Chair Time |
8:00 pm | Dinner |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:28 am | Microbes and Parasites |
9:00 am - 9:04 am | Discussion Leader: Richard Cummings (Emory University School of Medicine) |
9:04 am - 9:25 am | Adam Godzik (Sanford-Burnham Medical Research Institute)
"Toward the Complete Repertoire of Carbohydrate Binding Domains in Bacteria" |
9:25 am - 9:32 am | Discussion |
9:32 am - 9:54 am | Irma van Die (VU University Medical Center)
"Immune Regulation by Helminth Glycans" |
9:54 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:51 am | Markus Aebi (ETH Zürich)
"Glycotargets - Fungal Defense Strategies Against Predators and Parasites" |
10:51 am - 10:59 am | Discussion |
10:59 am - 11:07 am | Poster Presenter: Kaspar Locher (ETH Zurich)
"The Molecular Basis of N-Linked Protein Glycosylation" |
11:07 am - 11:11 am | Discussion |
11:11 am - 11:19 am | Poster Presenter: Mario Feldman (University of Alberta)
"Cell Surface Glycans are Involved In Protein Cargo Selection into Bacterial Vesicles from an Oral Pathogen" |
11:19 am - 11:23 am | Discussion |
11:23 am - 11:28 am | Chair Time |
11:28 am - 12:30 pm | Immunology and Immune Response |
11:28 am - 11:32 am | Discussion Leader: James Paulson (The Scripps Research Institute) |
11:32 am - 11:53 am | Robert Sackstein (Harvard Medical School)
"Functional Pleiotropisms of E-selectin Ligands" |
11:53 am - 12:01 pm | Discussion |
12:01 pm - 12:09 pm | Poster Presenter: Alan Cross (University of Maryland School of Medicine)
"Sialyl residues modulate LPS-mediated signaling through the Toll-like receptor 4 complex" |
12:09 pm - 12:13 pm | Discussion |
12:13 pm - 12:21 pm | Poster Presenter: Meike Scharenberg (University of Basel)
"Distinct Binding Modes for Substituted Lewis Structures to DC SIGN" |
12:21 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | Chair Time |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 6:28 pm | Immunology and Immune Response (continued) |
| Discussion Leader: James Paulson (The Scripps Research Institute) |
5:30 pm - 5:51 pm | Robert Antony (The Rockefeller University)
"Regulation of Inflammation by the IgG Fc Glycan" |
5:51 pm - 5:59 pm | Discussion |
5:59 pm - 6:20 pm | Teunis Geijtenbeek (Academic Medical Center, University of Amsterdam)
"C-type Lectin Signaling in Infection and Immunity" |
6:20 pm - 6:28 pm | Discussion |
6:28 pm - 7:30 pm | Award Winning Posters |
| Discussion Leader: Nancy Dahms (Medical College of Wisconsin) |
6:28 pm - 6:36 pm | Poster Presenter: Flavio Schwartz (ETH Zurich)
"N-Linked protein glycosylation: new surprises form bacteria" |
6:36 pm - 6:39 pm | Discussion |
6:39 pm - 6:47 pm | Poster Presenter: Kelvin Luther (University of Zurich)
"A Mimivirus Enzyme Confirms the Existence of Collagen Glycosylation Outside the Domains of Life" |
6:47 pm - 6:50 pm | Discussion |
6:50 pm - 6:58 pm | Poster Presenter: Cecilia D'Alessio (Fundacion Instituto Leloir/Conicet/UBA)
"In Vivo assessment of glucosidase II as a regulator of Glycoprotein Permanence in Calnexin/Calreticulin Cycles" |
6:58 pm - 7:01 pm | Discussion |
7:01 pm - 7:09 pm | Poster Presenter: Elisabeth Mohorko (ETH Zurich)
"Structure and Mechanism of N33/Tusc3, a Redox Active Subunit of the Human OligosaccharyItransferase Complex" |
7:09 pm - 7:13 pm | Discussion |
7:13 pm - 7:21 pm | Poster Presenter: Sakari Kellokumpu (University of OULU)
"The processing and Terminal Maturation of N-glycans in the Golgi of Live Cells Involves Two Distinct N-Glycosyltransferase Enzyme Complexes" |
7:21 pm - 7:25 pm | Discussion |
7:25 pm - 7:30 pm | Chair Time |
7:30 pm - 8:00 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
8:00 pm | Dinner |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Glycan Structure and Recognition |
9:00 am - 9:04 am | Discussion Leader: Ronald Schnaar (The Johns Hopkins University) |
9:04 am - 9:24 am | Kurt Drickamer (Imperial College)
"Characterisation of Novel Glycan-binding Receptors and Their Interactions with Intracellular Signaling Pathways" |
9:24 am - 9:32 am | Discussion |
9:32 am - 9:54 am | Fred Brewer (Albert Einstein College of Medicine)
"Lectin-Glycan Interactions in Cell Homeostasis and Innate Immunity" |
9:54 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:51 am | Robert Woods (University of Georgia)
"Combining Computational Methods with Glycan Array Data to Define the 3D Epitope of an Anti-tumor Antibody" |
10:51 am - 10:59 am | Discussion |
10:59 am - 11:20 am | William Balch (The Scripps Research Institute)
"Emergent Properties of Proteostasis in ER/Golgi Health and Disease" |
11:20 am - 11:28 am | Discussion |
11:28 am - 11:35 am | Poster Presenter: Helen Blanchard (Griffith University)
"Rotavirus recognition of cell surface carbohydrates" |
11:35 am - 11:39 am | Discussion |
11:39 am - 11:47 am | Poster Presenter: Thomas Peters (University of Lubeck)
"Sweet Recognition - NMR Studies into Norovirus-Receptor Recognition" |
11:47 am - 11:51 am | Discussion |
11:51 am - 11:59 am | Poster Presenter: Mark Agostino (Monash Institute of Pharmaceutical Sciences)
"In silico mapping approaches for investigating carbohydrate-antibody recognition and Carbohydrate-peptide Mimicry" |
11:59 am - 12:02 pm | Discussion |
12:02 pm - 12:10 pm | Poster Presenter: Leonardus Koharudin (University of Pittsburgh)
"A Novel anti-HIV lectin: Structure and Carbohydrate Specificity" |
12:10 pm - 12:13 pm | Discussion |
12:13 pm - 12:21 pm | Poster Presenter: Robert Gauss (ETH Zurich)
"A Complex of Pdi1p and Htm1p Initiates Clearance of Unfolded Glycoprotein's from the Endoplasmic Reticulum" |
12:21 pm - 12:24 pm | Discussion |
12:24 pm - 12:30 pm | Chair Time |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | Glycomics and GlycoChemistry |
5:30 pm - 5:34 pm | Discussion Leader: Anne Dell (Imperial College) |
5:34 pm - 5:55 pm | David Vocadlo (Fraser University)
"The Chemical Biology of O-GlcNAc Processing Enzymes" |
5:55 pm - 6:03 pm | Discussion |
6:03 pm - 6:24 pm | Rob Field (John Innes Centre)
"Dissecting the Molecular Basis of Starch Metabolism in Germinating Barley Seeds" |
6:24 pm - 6:32 pm | Discussion |
6:32 pm - 6:53 pm | Linda C. Hsieh-Wilson (California Institute of Technology)
"Roles for Chondroitin Sulfate in Axon Regeneration and Spinal Cord Injury" |
6:53 pm - 7:01 pm | Discussion |
7:01 pm - 7:09 pm | Poster Presenter: Tracey Gloster (Simon Fraser University)
"Hijacking a Biosynthetic Pathway Yields a Glycosyltransferase Inhibitor within Cells" |
7:09 pm - 7:12 pm | Discussion |
7:12 pm - 7:20 pm | Poster Presenter: Danielle H. Dube (Bowdoin College)
"Metabolic profiling of Helicobacter pylori glycosylation" |
7:20 pm - 7:23 pm | Discussion |
7:23 pm - 7:30 pm | Chair Time |
8:00 pm | Dinner |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |