Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Glycans in Development
Roles glycans, glycoproteins,
and glycolipids play in organismal development will be presented.
Discussion Leader: Elsenoor Klaver (University of Georgia, USA)
3:45 pm - 3:55 pm
Sarah Konze (Hannover Medical School, Germany)
"Glycoproteomic Analysis of Human Pluripotent Stem Cells and Stem
Cell-Derived Cardiomyocytes"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
Nian Wu (Imperial College London, United Kingdom)
"Characterization
of a Keratan Sulfate Antigen Expressed on Human-Induced Pluripotent Stem and
Embryonic Stem Cells by Glycosaminoglycan Designer Microarrays"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
Barbara Eckmair (University of Natural Resources and Life Sciences, Vienna, Austria)
"Analysis of Anionic N-Linked Glycans by MALDI-TOF Mass Spectrometry of Echinodermata
Species"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Glycans in Disease
The roles of glycans, glycoproteins, and glycolipids in the pathophysiology of glycan-related disorders will be presented.
Discussion Leader: Nickita Mehta (Ragon Institute of MGH, Harvard and MIT, USA)
7:30 pm - 7:40 pm
Jesus Aguilar Diaz de Leon (Arizona State University, USA)
"Interleukin-6 Modulates Glycan Structure of Glycoproteins Secreted by Hepg2 Cells"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Gaurang Bhide (University of Illinois at Chicago, USA)
"Protein-Specific Polysialylation: Substrate Hierarchies and Inhibition"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Panida Lertkiatmongkol (BloodCenter of Wisconsin, USA)
"Contribution of PECAM-1 Glycans to Endothelial Cell Barrier Function"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
David Nix (Complex Carbohydrate Research Center, University of Georgia, USA)
"Glycosylation and Innate Immunity in a Murine Model of Alzheimer's Disease"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Nithya Selvan (University of Georgia, USA)
"Understanding Causality of O-GlcNAc Transferase Mutations in X-Linked Intellectual Disability"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Marek Whitehead (University of Zurich, Switzerland)
"The Kiss of Death by Artificial Sialylation of Mammalian Cells"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Timm Fiebig (Hannover Medical School, Germany)
"An Efficient
Enzyme-Based Solid-Phase Synthesis of Meningococcal Capsular Oligosaccharides"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Roisin O'Flaherty (National Institute for Bioprocessing Research and Training (NIBRT), Ireland)
"High-Throughput
Sequential Glycoprofiling of Six Abundant Glycoproteins Igg, Iga, Igm,
Transferrin, Haptoglobin and Alpha-1-Antitrypsin in Ovarian Cancer"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Glycans in Host-Pathogen/Symbiont Interactions
The roles of glycans, glycoproteins, and glycolipids in interactions between host, microbes, and parasites will be discussed.
Discussion Leader: Simone Kurz (Complex Carbohydrate Research Center, University of Georgia, USA)
9:00 am - 9:10 am
Andreia Albuquerque (Hannover Medical School, Germany)
"Characterization of Apicomplexan Parasites C-Mannosyltransferases"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
Jessica Bevan (Instituto de Medicina Molecular (IMM), University of Lisbon, Portugal)
"Development of Immobilized Affinity Based Probes for Selective Enrichment of Glycosyltransferases in Trypanosoma brucei "
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Karen Coss (King's College London, United Kingdom)
"Longitudinal
Glycoprofiling of Gp120s in an HIV-1 Infected Patient"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Tamir Dingjan (Monash University, Australia)
"In Silico Exploration of Burkholderia Ambifaria Lectin Binding to Blood Group Determinants for the Discovery of Glycomimetic Inhibitors"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Francesca Martini (Malcisbo AG, Switzerland)
"N-Glycan
Profiling of Dirofilaria Immitis: Revealing Potential Immunogenic Components of
the Canine Heartworm"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Gisela Weiss (University of Zurich, Switzerland)
"Metabolic Incorporation of Azido Sugars in Commensal Gut Bacteria"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Jana Fuehring (Hannover Medical School, Germany)
"Understanding
Catalytic and Allosteric Mechanisms in UDP-Glucose Pyrophosphorylases: Towards
Utilizing Conserved Enzymes as Novel Drug Targets"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Elda Iljazi (University of Dundee, United Kingdom)
"Defining D-Arabinose Metabolism in Leishmania Major and Crithidia Fasciculata"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leader: Timm Fiebig (Hannover Medical School, Germany)
1:30 pm - 1:35 pm
Introduction by Discussion Leader
1:35 pm - 2:25 pm
Panel Discussion
Career Mentoring
Linda Baum (University of California, Los Angeles, USA)
Karen Colley (University of Illinois at Chicago, USA)
Jeffrey Esko (University of California, San Diego, USA)
2:25 pm - 2:30 pm
Closing Remarks
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
