Frontiers of Science

Find a Conference

Alert - GRC systems are offline for approximately one week. For more information, please click here.

Glycobiology (GRS)

Gordon Research Seminar

Developments and Technologies to Advance the Understanding of the Glycome in Health and Disease

March 9 - 10, 2019

Chair Jana I. Fuehring

Renaissance Tuscany Il Ciocco

Via Giovanni Pascoli

Lucca (Barga), Lucca, Italy

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Glycobiology is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The aim of this meeting is to present and discuss recent insights into all aspects of the synthesis, structure and function of glycans, as well as their roles in development, physiology, immunology and genetic or infectious disease. Topics will encompass the tasks of glycans in communication and interaction between cells and their surroundings in healthy and diseased states, but also novel methods, technologies, models and applications. A mentoring session will conclude the meeting.

Related Meeting

This GRS will be held in conjunction with the "Glycobiology" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:30 pm - 4:30 pm	Arrival and Check-in
3:00 pm - 3:15 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm	Engineering and Utilizing Glycans Discussion Leader: Markus Abeln (Hannover Medical School, Germany)
3:15 pm - 3:25 pm	Francis Santens (VIB, Ghent University, Belgium) "GlycoDelete: Engineering of Protein Production Systems to Drastically Reduce Glycan Heterogeneity of Biopharmaceuticals"
3:25 pm - 3:30 pm	Discussion
3:30 pm - 3:40 pm	Melissa Gray (Stanford University, USA) "Engineering Antibody-Sialidase Conjugates for Targeted Removal of Sialic Acids on the Cancer Cell Glycocalyx"
3:40 pm - 3:45 pm	Discussion
3:45 pm - 3:55 pm	Jessica Stark (Northwestern University, USA) "A Cell-Free Platform for Point-of-Care Production of Glycoprotein Therapeutics and Bioconjugate Vaccines"
3:55 pm - 4:00 pm	Discussion
4:00 pm - 5:30 pm	Poster Session
5:30 pm - 7:30 pm	Exploring and Understanding the Complexity of the Glycome Discussion Leader: Benjamin Meyer (University of Duisburg-Essen, Germany)
5:30 pm - 5:40 pm	Ilaria Arigoni-Affolter (ETH Zürich, Switzerland) "In Vivo Monitoring, Analysis and Modeling of Monoclonal Antibody N-Glycosylation Kinetics in CHO Cells"
5:40 pm - 5:45 pm	Discussion
5:45 pm - 5:55 pm	Weston Kightlinger (Northwestern University, USA) "Site-Specific Control of Protein Glycosylation by Rapid Discovery of Unique Glycosyltransferase Activities"
5:55 pm - 6:00 pm	Discussion
6:00 pm - 6:10 pm	Charlotte Rossdam (Hannover Medical School, Germany) "CGE-LIF as a Novel Approach for the Analysis of Glycosphingolipid-Derived Glycans"
6:10 pm - 6:15 pm	Discussion
6:15 pm - 6:25 pm	Kathirvel Alagesan (Institute for Glycomics, Griffith University, Australia) "Better Together: Relative Retention Time Plus Spectral Matching Improves Automated Glycan Characterisation Using PGC-nLC-IT-ESI-MSMS"
6:25 pm - 6:30 pm	Discussion
6:30 pm - 6:40 pm	Katarina Madunic (Leiden University Medical Center, The Netherlands) "Colorectal Cancer Cell Lines Reveal Striking Isomeric Diversity of the Human Cancer O-Glycome"
6:40 pm - 6:45 pm	Discussion
6:45 pm - 6:55 pm	Joel Bloch (ETH Zurich, Switzerland) "Structural Studies of ER-Based Glycosyltransferases"
6:55 pm - 7:00 pm	Discussion
7:00 pm - 7:10 pm	Malena Albers (Hannover Medical School, Germany) "O-Acetylation of Sialoglycans: The Role of the Acetyl-CoA Transporter AT-1"
7:10 pm - 7:15 pm	Discussion
7:15 pm - 7:25 pm	Simon Wisnovsky (Stanford University, USA) "Translating the Cancer Glyco-Code with Genome-Wide CRISPR Screens"
7:25 pm - 7:30 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Glycans in Health and Disease Discussion Leader: Kathirvel Alagesan (Institute for Glycomics, Griffith University, Australia)
9:00 am - 9:10 am	Colleen Britain (University of Alabama at Birmingham, USA) "Glycosyltransferase ST6Gal-I Promotes the Epithelial to Mesenchymal Transition Through the Sialylation of EGFR and Increases Pancreatic Cancer Metastasis"
9:10 am - 9:15 am	Discussion
9:15 am - 9:25 am	Yvette Luijkx (Utrecht University, The Netherlands) "Probing the Dynamic Role of Fucose in Our Gut-Microbiome Homeostasis via a Chemical Biology Approach"
9:25 am - 9:30 am	Discussion
9:30 am - 9:40 am	Kaitlyn Dorsett (University of Alabama at Birmingham, USA) "Sox2 Drives ST6Gal-I Expression and Activity to Promote a CSC Phenotype in Ovarian Cancer"
9:40 am - 9:45 am	Discussion
9:45 am - 9:55 am	Marine Houdou (Unité de Glycobiologie Structurale et Fonctionnelle (UMR 8576, CNRS), University of Lille, France) "TMEM165: A New Key Player in Golgi Glycosylation and Cellular Mn²⁺ Homeostasis"
9:55 am - 10:00 am	Discussion
10:00 am - 10:10 am	John Cipollo (Center for Biologics Evaluation and Research, FDA, USA) "Influenza Hemagglutinins H2, H5, H6, and H11 Are Not Targets of Pulmonary Surfactant Protein D: Structural Prediction and Confirmation of N-Glycan Sub-Type as a Pathogenic Factor in Influenza"
10:10 am - 10:15 am	Discussion
10:15 am - 10:25 am	Sumeyye Cavdarli (Unité de Glycobiologie Structurale et Fonctionnelle (UMR 8576), CNRS / University of Lille, France) "Identification of 9-O-Acetyl-N-Acetylneuraminic Acid (Neu5,9Ac2) as Main O-Acetylated Sialic Acid Species of GD2 in Breast Cancer Cells"
10:25 am - 10:30 am	Discussion
10:30 am - 10:40 am	Joscha Meiers (Helmholtz-Zentrum für Infektionsforschung, Germany) "Targeting Antibiotics via Carbohydrate Probes Against Pseudomonas aeruginosa Biofilm"
10:40 am - 10:45 am	Discussion
10:45 am - 10:55 am	Eline Blommaert (KU Leuven, Belgium) "MAGT1-CDG vs. XMEN: Two Faces of the Same Glycosylation Disorder?"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Career Panel Discussion Leader: Sarah Konze (Hannover Medical School, Germany)
1:30 pm - 2:30 pm	Panel Discussion Career Mentoring Kiyoko Aoki-Kinoshita (Soka University, Japan) Mark von Itzstein (Griffith University, Australia) Nora Heisterkamp (Beckman Research Institute, City of Hope, USA) Vlad Panin (Texas A&M University, USA)
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

Contributors

Research reported in this publication was supported by the National Institute of Dental and Craniofacial Research of the National Institute of Health under Award Number R13DE026693. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Health.

Conference Links

Conference History Glycobiology

Similar Conferences

Registration Fees Additional Fee Info

Similar Gordon Research Conferences and Seminars

Glycobiology

March 23 - 28, 2025

Contact Us

MyGRC Account
Check your application status, complete your registration, update your poster, change your rooming preference, make a bus reservation, print an invitation letter, print a receipt (which includes verification that you are presenting a poster) or print an invoice by logging into your account.

GRC Venues
Everything you need to know, to plan your trip.

FAQs
Instant answers to common questions.

Tell us how we can help

Call us and leave a detailed message at: 401-783-4011

*This voicemail is only checked once daily. Due to high volume of requests during the conference season, responses may be delayed.

You have no notifications