Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Regulation of Glycosylation
Discussion Leader: Nicholas Riley (Stanford University, United States)
3:45 pm - 4:00 pm
Andrew Alexander (ETH Zürich, Switzerland)
"Structural and Functional Analysis of ALG9: a Human Endoplasmic Reticulum a1,2-Mannosyltransferase"
4:00 pm - 4:05 pm
Discussion
4:05 pm - 4:20 pm
Lola Fagbami (University of Georgia, United States)
"Elucidating the Mechanism of N-linked Glycosylation in Human Malaria Parasites"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Chemical and Molecular Analysis of Glycosylation
Discussion Leader: Fiona Kearns (University of California, San Diego, United States)
7:30 pm - 7:45 pm
Sarah Lowery (Yale University, United States)
"Coupled MALDI-MSI and LC-MS for Comprehensive O-Glycoproteomic Analysis of FFPE Mucinous Tumor Samples"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Jessica Stark (Stanford University, United States)
"Antibody-lectin Chimeras for Glyco-immune Checkpoint Blockade"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Mana Mukherjee (National Institutes of Health, United States)
"1,3-Pr2 -6-OTs GlcNAlk as Bioorthogonal Precursor for Specific Labeling of N-glycan Hybrid Structure"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Jaclyn Swan (UCSD, United States)
"The Sialome of the Human Retina"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Tiandi Yang (Harvard Medical School, United States)
"An Extra ECM-binding Matriglycan on Dystroglycan"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Nicholas Riley (Stanford University, United States)
"Deciphering O-glycoprotease Substrate Preferences with O-Pair Search"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Glycans in Health and Disease
Discussion Leader: Jaclyn Swan (UCSD, United States)
9:00 am - 9:15 am
Priti Gupta (Gothenburg University, Sweden)
"Effects of Estrogen on IgG Glycosylation and Total Serum Protein Glycosylation"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Rohit Budhraja (Mayo clinic, United States)
"N-glycoproteomic Profiling of Phosphoglucomutase 2 (Pgm2) Knockout Mouse Heart Reveals Distinct Glycosylation Pattern"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Beatriz Calle (Francis Crick Institute, United Kingdom)
"A Chemical Biology Approach to Characterise the Glycoproteome of Breast Cancer"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Lauren Gandy (Rensselaer Polytechnic Institute, United States)
"Defining the Interaction of HSV-1 Glycoprotein D and Heparan Sulfate: Implications for Alzheimer’s Disease and Herpes Viral Entry"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Fiona Kearns (University of California, San Diego, United States)
"Atomic Scale Exploration of Respiratory Mucins and their Interactions with SARS-CoV-2 Spike"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Vienvilay Phandanouvong Lozano (University of California Berkeley, United States)
"Interrogating the Preferential Catabolism of Dietary Sialic Acids by the Gut Microbiota"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Careers in Glycoscience
Discussion Leaders: Simon Wisnovsky (University of British Columbia, Canada)
1:30 pm - 2:30 pm
Panel Discussion
Careers in Glycoscience
Lance Wells (University of Georgia, United States)
Daniel Kolarich (Institute for Glycomics, Griffith University, Australia)
Karin Hoffmeister (Versiti Blood Research Institute, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes