SATURDAY |
1:00 pm - 5:00 pm | Arrival and Check-in |
3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chairs Randal Westrick and Zachary Fulkerson |
3:15 pm - 4:00 pm | Keynote Lecture |
| Discussion Leader: Peter Gross, M.D. (McMaster University and Henderson Research Centre, Canada) |
3:15 pm - 3:45 pm | Jay Degen, Ph.D. (Cincinnati Children's Hospital Medical Center) "Hemostatic factors and the control of inflammatory disease processes in vivo" |
3:45 pm - 4:00 pm | Discussion |
4:00 pm - 6:00 pm | Poster Session: Hemostasis A |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Coagulation Factors |
| Discussion Leader: Sandra Haberichter, Ph.D. (Medical College of Wisconsin) |
7:30 pm - 7:45 pm | Mettine Bos (Children’s Hospital of Philadelphia) "Conserved Structural Motifs Cooperate to Maintain Blood Coagulation Factor V in an Inactive Procofactor State" |
7:45 pm - 7:55 pm | Discussion |
7:55 pm - 8:10 pm | Jeremy Wood (University of Vermont) "Characterizing the N-Linked Glycosylation of Factor Va Using Mass Spectrometry" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:35 pm | Paul R. Hess (University of Pennsylvania)
"Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling" |
8:35 pm - 8:45 pm | Discussion |
8:45 pm - 9:00 pm | Jongseong Kim (Harvard) "The Flex-Bond, a Mechanically Stabilized Receptor-Ligand Bond Important in the Vasculature" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Nikolett Wohner (Semmelweis University) "Proteolysis of von Willebrand factor under shear stress" |
9:25 pm - 9:30 pm | Discussion |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 9:30 am | Strategies for Mentored Career Development |
| Discussion Leader: Zachary Fulkerson (University of Kentucky) |
9:00 am - 9:15 am | David Motto, M.D., Ph.D. (University of Iowa) |
9:15 am - 9:25 am | Discussion |
9:25 am - 11:20 am | Platelet Biology |
| Discussion Leader: Sidney Whiteheart, Ph.D. (University of Kentucky) |
9:25 am - 9:40 am | Peisong Ma (University of Pennsylvania) "Decay of a tyrosine phosphorylated RGS/SPL/SHP-1 protein complex regulates platelet activation in an agonist-selective manner" |
9:40 am - 9:50 am | Discussion |
9:50 am - 10:05 am | Lea Beaulieu (Boston University) "IL1R1 and IL1beta Affect Platelet Development and Function" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:25 am | Coffee Break |
10:25 am - 10:40 am | William Kaiser (University of Reading, England) "Heat shock protein 47 appears to behave as a platelet collagen receptor" |
10:40 am - 10:50 am | Discussion |
10:50 am - 11:05 am | Todd Getz (Temple University) "Evaluation of the role of classical PKC isoforms in GPVI-mediated platelet functional responses" |
11:05 am - 11:15 am | Discussion |
11:15 am - 12:30 pm | Special Topics |
| Discussion Leader: Peter Gross, M.D. (McMaster University and Henderson Research Centre, Canada) |
11:15 am - 11:30 am | Nathan Hudson (University of North Carolina)
"Strain Stiffening of Individual Fibers Allows Fibrin Networks to withstand Higher Forces" |
11:30 am - 11:40 am | Discussion |
11:40 am - 11:55 am | Robert Campbell (University of Utah) "Platelets synthesize urokinase plasminogen activator receptor" |
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:20 pm | Jolanta Amblo (University of Vermont) "Quantitative analysis of carbohydrates of natural and recombinant human tissue factor" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 3:30 pm | Poster Session: Hemostasis B |
3:30 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |